Navigation Links
Researchers observe an increased risk of cancer in people with history of non-melanoma skin cancer
Date:4/23/2013

Boston, MA A prospective study by researchers at Brigham and Women's Hospital (BWH) observed an association between risk of second primary cancer and history of non-melanoma skin cancer in white men and women.

The researchers found that people with a history of non-melanoma skin cancer had a modestly increased risk of getting cancer in the future, specifically breast and lung cancer in women and melanoma in both men and women. Non-melanoma skin cancer, which includes basal cell and squamous cell carcinoma, is the most common form of cancer in the United States.

The study will be published on April 23, 2013 in PLOS Medicine.

The researchers analyzed data from two large United States cohort studiesthe Health Professionals Follow-up Study and the Nurses' Health Study. The researchers followed 46,237 men from June 1986 to June 2008 in the Health Professionals Follow-up Study, and 107,339 women from June 1984 to June 2008 in the Nurses' Health Study. The researchers identified 36,102 new cases of non-melanoma skin cancer and 29,447 new cases of other primary cancers.

A history of non-melanoma skin cancer was significantly associated with a 15 percent higher risk of other primary cancers in men, and a 26 percent higher risk of other primary cancers in women. When melanoma was excluded from this analysis, the rates changed slightly, with a history of non-melanoma skin cancer associated with an 11 percent higher risk of other primary cancers in men, and a 20 percent higher risk of other primary cancers in women.

After using statistical models to correct for multiple comparisons, looking at individual cancer sites, the researchers found that a history of non-melanoma skin cancer was significantly linked to an increased risk of breast and lung cancer in women, and an increased risk of melanoma in both men and women.

According to the researchers, these findings should be interpreted cautiously.

"Because our study was observational, these results should be interpreted cautiously and are insufficient evidence to alter current clinical recommendations," said Jiali Han, PhD, Channing Division of Network Medicine, BWH Department of Medicine and BWH Department of Dermatology. "Nevertheless, these data support a need for continued investigation of the potential mechanisms underlying this relationship."


'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
Source:Eurekalert

Related medicine news :

1. Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
2. Deficiency in p53 anti-tumor protein delays DNA repair after radiation, Moffitt researchers say
3. Wayne State researchers seek calcium channels to target cancer tumors
4. 3 Mass. General researchers among recipients of Clinical Research Achievement awards
5. Researchers identify and block protein that interferes with appetite-suppressing hormone
6. Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
7. Stanford researchers turn skin cells directly into the cells that insulate neurons
8. NYU researchers offer 12 principles for effective contraceptive counseling
9. Most effective PTSD therapies are not being widely used, researchers find
10. Gabriel Hortobagyi honored for mentoring minority researchers
11. Researchers develop tool to assist areas of infectious disease outbreaks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... California (PRWEB) , ... June ... ... pioneer in the patient payment industry today announced its strategic partnership with ... health system workflows. , The two companies’ proven, proprietary technology combine to ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating ... Millions of individuals in the United States and Canada wear eyeglasses. Once considered to ... correct vision and make a fashion statement. Even celebrities use glasses as a way ...
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women ... diagnosed with endometriosis. These women need a treatment plan to not only alleviate ... that can help for preservation of fertility and ultimately achieving a pregnancy. The ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
Breaking Medicine Technology: