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Researchers identify new drug target for treating jet lag and shift work disorders
Date:8/30/2013

our society, with Thomas Edison's light bulbs, Nikola Tesla's electricity, and jet airplanes, that we begin to realize our biological limitations," Duffield said.

The researchers' identification of the role SIK1 plays in the body clock offers a tractable target for drugs that could help us adjust faster to changes in time zone and help ameliorate the effects of rotational shift work.

"The fact that it is a kinase enzyme makes it an attractive target for the design of novel therapeutics," Duffield added.

Flanagan worked on the project as an undergraduate student, writing an honor thesis on his research data and presented his work at the Society for Research on Biological Rhythms meeting in 2012.

"Being involved in this project as an undergraduate student and presenting my data at an international conference really crystalized my interest in scientific research as a career," Flanagan said.


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Contact: Giles Duffield
Giles.E.Dufield.2@nd.edu
574-631-1834
University of Notre Dame
Source:Eurekalert

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