Navigation Links
Researchers identify new drug target for treating jet lag and shift work disorders
Date:8/30/2013

University of Notre Dame researchers, as part of a collaborative effort, have identified a protein that potentially could be a target for drugs that that would help people recover faster from jet lag and better adjust their circadian rhythms during rotational shift work. The study appears in the Aug. 29th issue of the journal Cell. It can be found at: http://www.sciencedirect.com/science/article/pii/S0092867413009616

An internal circadian body clock helps virtually all creatures synchronize their bodily functions to the 24-hour cycle of light and dark in a day. However, travel to a different time zone, or shift work, disrupts the body's clock. Furthermore, it can take up to a day for the body to adjust to each hour that the clock is shifted, resulting in several days of fatigue, indigestion, poorer cognitive performance and sleep disturbance.

Giles Duffield, associate professor of biological sciences at Notre Dame and a member of the University's Eck Institute for Global Health, and Kevin Flanagan, a University alumnus and now a doctoral student at Washington University in St. Louis, characterized the protein SIK1, revealing that it plays a pivotal role in preventing the body from adjusting too quickly to changes in the environment.

Duffield and Flanagan, along with researchers from University of Oxford and F. Hoffman La Roche, and led by senior research scientist Stuart Peirson at the Nuffield Department of Clinical Neurosciences, identified roughly 100 genes that the body switches on in response to light, initiating a series of events that help to retune the body clo
'/>"/>

Contact: Giles Duffield
Giles.E.Dufield.2@nd.edu
574-631-1834
University of Notre Dame
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Researchers develop a new cell and animal model of inflammatory breast cancer
3. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
4. Researchers Find Gene Mutations That May Be a Key to Autism
5. Researchers find evidence of banned antibiotics in poultry products
6. NJ stroke researchers report advances in spatial neglect research at AAN Conference
7. Autism by the numbers: Yale researchers examine impact of new diagnostic criteria
8. Researchers Map Brain Regions Linked to Intelligence
9. Researchers ID Genes That May Determine Mental Illness
10. Researchers Develop Blood Test for Depression
11. University of Cincinnati researchers win $3.7M grant from US Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... Discount-Dress.com, a company that specializes ... its decision to implement a new shopping cart software ... across the world. Furthermore, the company has unveiled a ... , The new items come in fashionable designs; all ... to 56 percent off. "We are happy to release ...
(Date:9/21/2014)... High in the rugged Gore Range ... able-bodied athletes rafted the Colorado River, rode mountain bikes ... pursuit of outdoor adventure. At the September 12-14 ... Sports, disabilities proved to be no more than an ... stage event. , Each participating team of five athletes ...
(Date:9/21/2014)... 21, 2014 Recently, BambooIndustry.com, an experienced ... offer for its bamboo panels ( http://www.bambooindustry.com/products/bamboo-panel/ ). The ... all of them are available at discounted prices now, ... company’s discounted bamboo panels are available in ... quality materials. Each of them is finely manufactured by ...
(Date:9/21/2014)... According to latest National Vital Statistics Reports ... 1966 (10.5 births per 1,000 women in 2013). Since 2000, ... steadily by 2 percent per year. The birth rate for ... and over) also rose, the first such increase since 2008. ... times as many first births to women aged 35 and ...
(Date:9/20/2014)... (PRWEB) September 21, 2014 Diabetes ... Kenneth Pullman that is helping thousands of people learn ... symptoms without shots, pills, or prescriptions has caught the ... , “There are currently tens of millions of people ... 1 and Type 2 diabetes, and unfortunately, big pharma ...
Breaking Medicine News(10 mins):Health News:Discount-Dress.com Implements A New Shopping Cart Software And Provides New Beach Wedding Dresses 2Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 2Health News:Disabled Athletes Excel at World T.E.A.M. Sports’ Adventure Team Challenge 3Health News:Discounted Bamboo Panels For Sale At BambooIndustry.com 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 2Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 3Health News:Statistics Reveal That the Number of 'Older' First-Time Mothers Is Growing 4Health News:Diabetes Protocol: Review Exposes Kenneth Pullman’s Breakthrough Discovery About Diabetes Management 2
... (ACP) today commended Congress for taking bipartisan action to ... by stabilizing physician payments through 2011. The College ... to enact legislation to provide longer-term stability in payments ... (SGR) formula. The legislation, passed unanimously ...
... News) -- There,s no scientific evidence that stricter testing ... federal food and nutrition programs would improve the safety ... Council report released Thursday. The authors based their ... Agriculture,s Agricultural Marketing Service,s (AMS) program, which is used ...
... Kathleen Doheny HealthDay Reporter , THURSDAY, Dec. ... drugs often prescribed to breast cancer patients, may ... according to a Canadian researcher. ,There have always ... Princess Margaret Hospital in Toronto, who is scheduled to ...
... new study shows that a new type of targeted ... good as surgery for patients aged 75 and older ... the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. This ... Oncology (ASTRO), the American Society of Clinical Oncology (ASCO), ...
... of the children,s television show Sesame Street, had improved ... by researchers at the Johns Hopkins Bloomberg School of ... had the greatest exposure to Jalan Sesama improved significantly ... social awareness, compared to those with no or low ...
... MI 9 December, 2010 The 19th International ... (CPMRC), an Elsevier company and leader in assisting healthcare ... focus on transformational leadership and feature advice from many ... Visa, Inc.. "The essence of transformation, real ...
Cached Medicine News:Health News:ACP commends Congress for preserving patient access by stopping scheduled Medicare SGR cuts 2Health News:No Scientific Proof Backing Stricter Tests of Ground Beef in School Lunches 2Health News:Certain Breast Cancer Drugs Linked With Heart Risks in Older Women 2Health News:Certain Breast Cancer Drugs Linked With Heart Risks in Older Women 3Health News:Non-invasive SRT as good as surgery for elderly patients with early lung cancer 2Health News:Sesame Street program improves development for children in Indonesia 2Health News:Transformation at top of agenda for CPMRC's annual conference in Jan. 2011 2
(Date:9/19/2014)... , Sept. 19, 2014  The board of directors ... a quarterly cash dividend of $0.42 per share.  ... 2014 to stockholders of record at the close of ... AbbVie is a global, research-based biopharmaceutical company formed in ... to use its expertise, dedicated people and unique approach ...
(Date:9/19/2014)... Medical announces the formal launch of the largest ... on the market today at this weekend,s American Orthopaedic ... Chicago .  The Osteotomy Truss System is a comprehensive ... size options included in one versatile set. Previously available ... 18 implant sizes, which limited a surgeon,s ability to ...
(Date:9/19/2014)... 2014 The American Association for Homecare (AAHomecare) ... Manufacturing has joined the AAHomecare Corporate Partner Program. ... have been actively involved in AAHomecare for much ... quickly grown into a major global manufacturer of home ... AAHomecare to increase efforts on behalf of the HME ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2
... Radianse active-RFID-tags can be ... For example, that a device ... complete or that a patient ... Every message from an ID-tag ...
PDC RFID Smart™ Cards can be printed and programmed using a dye-sublimation card printer & programmer....
PDC Smart® Wrist Tag provides read/write and data storage capabilities....
... helps protect infants, patients, staff, and vital ... cost savings, and overall peace of mind ... healthcare facilities., And with HALO, youre not ... solution, but also unique-skin sensing RFID tags ...
Medicine Products: