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Researchers help confirm value of flow-diverting device for most challenging aneurysms
Date:1/30/2013

CINCINNATIA multi-center study supports the effectiveness of the newest technology available for the treatment of difficult, life-threatening brain aneurysms. The technology, the Pipeline embolization device, is a flow diverter that redirects blood flow away from wide-necked or giant aneurysms that cannot be treated in more conventional ways.

Andrew Ringer, MD, director of the division of cerebrovascular surgery and professor of neurosurgery and radiology at the University of Cincinnati (UC) College of Medicine, led the Cincinnati portion of the study, which was published in the December issue of Neurosurgery.

"The study showed that the Pipeline device is a safe and effective tool for patients and surgeons," says Ringer, a Mayfield Clinic neurosurgeon who has treated 11 patients with the device. "This expands our ability to safely treat aneurysms that were very difficult to treat before."

A brain aneurysm is bulge on an artery wall that can rupture as it grows thinner and weaker, releasing blood into the space between the brain and the skull, a potentially catastrophic event called a subarachnoid hemorrhage. Of the 30,000 Americans who experience a ruptured brain aneurysm each year, according to the American Association of Neurological Surgeons, about 40 to 50 percent survive, while 20 percent recover without any permanent physical deficits.

The U.S. Food and Drug Administration approved the flow-diverting device in 2011 after the successful completion of a clinical trial known as PUFS (Pipeline for Uncoilable or Failed Aneurysms). Ringer and his colleagues from six other neurosurgical centersall part of the Endovascular Neurosurgery Research Group (ENRG)opted to continue studying the Pipeline, which is manufactured by ev3/Covidien, to better understand its safety and effectiveness in real-world hospital settings.

"Whenever there is a new device, technology or drug that is undergoing review for FDA appr
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Contact: Cindy Starr
cindy.starr@uc.edu
513-558-3505
University of Cincinnati Academic Health Center
Source:Eurekalert

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