Navigation Links
Research team recognizes predator-producing bacteria
Date:12/11/2012

Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say.

A team led by Lora V. Hooper, an associate professor of immunology and microbiology at The University of Texas Southwestern Medical Center, and including UT Arlington assistant professor of biology Jorge Rodrigues examined the bacteriophages, or phages, produced by genetic information harbored in the chromosome of the mammalian gut bacterium Enterococcus faecalis. They found that a phage unique to Enterococcus faecalis strain V583 in mice acts as a predator, infecting and harming other similar, competing bacterial strains. They believe these lab results suggest what goes on in the human intestine.

"This organism is using phage as a way to compete in your gut. If the phage is released and gets rid of all the other microbes, then strain V583 will have more nutrients available," Rodrigues said. "It opens up new questions about the role of phages in the gut system. Ultimately, you could use this as a technique to control bacteria in a natural way."

The findings were presented in October in the Proceedings of the National Academy of Sciences in a paper called, "A composite bacteriophage alters colonization by an intestinal commensal bacterium." It is available online here. Other co-authors were members of Hooper's lab: Breck A. Duerkop, Charmaine V. Clements and Darcy Rollins.

"Now that we've established the role of these bacteriophages, our team is working on trying to discover the specific triggers that lead to phage production in the gut," said Hooper, a Howard Hughes Medical Institute investigator. "We also want to understand whether there are other phages that play a role in shaping the composition of gut bacterial communities."

Bacteria are abundant in the human gastrointestinal tract, and scientists are increasingly trying to understand their role in human health. Of those bacteria, Enterococcus faecalis, also known asE. faecalis, can constitute as much as 0.5 to 0.9 percent of gut microflora, according to the researchers. Outside of the gut, E. faecalis can cause dangerous infections, such as endocarditis, and is often resistant to standard antibiotics like vancomycin.


'/>"/>

Contact: Traci Peterson
tpeterso@uta.edu
817-272-9208
University of Texas at Arlington
Source:Eurekalert

Related medicine news :

1. UAlberta medical researchers make key discovery in fight against Alzheimers disease
2. NIH scientists reflect on gains in emerging infectious disease awareness, research and response
3. 2 UT Southwestern scientists honored as rising stars in Texas research
4. Anti-aging gene identified as tumor suppressor in mice, research finds
5. Moffitt researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
6. Kinsey research: Postpartum women less stressed by threats unrelated to the baby
7. Family Counseling & Crisis Intervention Services in the US Industry Market Research Report from IBISWorld has Been Updated
8. Wayne State researcher finds possible clue to childrens early antisocial behavior
9. Pharmacy researcher finds most popular weight-loss drug strongly alters other drug therapies
10. Boston College researcher looks to stop a deadly parasite in its tracks
11. Survey shows breakthrough medical research relies heavily on NIH funding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... August 22, 2017 , ... ... to good health is as simple as eating healthy foods. But this well-known ... storing fat, making insulin, or breaking apart carbohydrates—depends not only on properties of ...
(Date:8/22/2017)... ... August 22, 2017 , ... Each of the past six years, Lightning Labels has sent ... these labels and stickers, demonstrating the variety and creativity of their designs. Submissions this year ... came in. Now, it's time to announce the winners of the sixth annual Photo Contest, ...
(Date:8/22/2017)... Metroplex, TX (PRWEB) , ... August 22, 2017 , ... Five Star Glass is new ... They provide repair and replacement of auto glass for most makes and models, in Grand ... in the USA. , They have been a family owned business for the past ...
(Date:8/22/2017)... ... , ... “Without Love’s Beauty and Pleasures Life Does Not ... while hoping for a better life. “Without Love’s Beauty and Pleasures Life Does ... 13 years working with deprived/neglected adolescents and almost 20 years working with adults ...
(Date:8/22/2017)... ... 22, 2017 , ... John Stewart joins Privis Health as ... t4 Leadership Development & Consulting. He has spent his career focusing on four ... development, servant leadership, data driven process improvement, and supportive technology. These key elements ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... a next-generation full-service pharmacy, has announced the launch of its ... Washington D.C. metropolitan area. CaryRx aims to ... through the convenience of its patient-friendly mobile app. Prescriptions can ... to any location in D.C. ... Washington D.C. ," says Areo Nazari , ...
(Date:7/28/2017)... Inc. ("Hill-Rom") (NYSE: HRC), today announced financial results for ... updated its financial outlook for fiscal 2017. ... quarter, Hill-Rom reported earnings of $0.09 per diluted share ... period. These results reflect after-tax special items, including a ... the non-cash write-down of assets associated with the planned ...
(Date:7/26/2017)... Medical Aesthetics, a leading medical aesthetic clinic in Singapore ... several skin conditions from the inside. The natural process ... The skin becomes more transparent due to the thinning of the ... from the sun contributes to aging skin, causing age spots and ... ...
Breaking Medicine Technology: