Navigation Links
Research team recognizes predator-producing bacteria
Date:12/11/2012

Unique viruses called bacteriophages may play an important role in competition among bacterial strains, influencing the overall ecosystem of the human intestine, scientists at The University of Texas at Arlington and UT Southwestern Medical Center say.

A team led by Lora V. Hooper, an associate professor of immunology and microbiology at The University of Texas Southwestern Medical Center, and including UT Arlington assistant professor of biology Jorge Rodrigues examined the bacteriophages, or phages, produced by genetic information harbored in the chromosome of the mammalian gut bacterium Enterococcus faecalis. They found that a phage unique to Enterococcus faecalis strain V583 in mice acts as a predator, infecting and harming other similar, competing bacterial strains. They believe these lab results suggest what goes on in the human intestine.

"This organism is using phage as a way to compete in your gut. If the phage is released and gets rid of all the other microbes, then strain V583 will have more nutrients available," Rodrigues said. "It opens up new questions about the role of phages in the gut system. Ultimately, you could use this as a technique to control bacteria in a natural way."

The findings were presented in October in the Proceedings of the National Academy of Sciences in a paper called, "A composite bacteriophage alters colonization by an intestinal commensal bacterium." It is available online here. Other co-authors were members of Hooper's lab: Breck A. Duerkop, Charmaine V. Clements and Darcy Rollins.

"Now that we've established the role of these bacteriophages, our team is working on trying to discover the specific triggers that lead to phage production in the gut," said Hooper, a Howard Hughes Medical Institute investigator. "We also want to understand whether there are other phages that play a role in shaping the composition of gut bacterial communities."

Bacteria are abundant in the human gastrointestinal tract, and scientists are increasingly trying to understand their role in human health. Of those bacteria, Enterococcus faecalis, also known asE. faecalis, can constitute as much as 0.5 to 0.9 percent of gut microflora, according to the researchers. Outside of the gut, E. faecalis can cause dangerous infections, such as endocarditis, and is often resistant to standard antibiotics like vancomycin.


'/>"/>

Contact: Traci Peterson
tpeterso@uta.edu
817-272-9208
University of Texas at Arlington
Source:Eurekalert

Related medicine news :

1. UAlberta medical researchers make key discovery in fight against Alzheimers disease
2. NIH scientists reflect on gains in emerging infectious disease awareness, research and response
3. 2 UT Southwestern scientists honored as rising stars in Texas research
4. Anti-aging gene identified as tumor suppressor in mice, research finds
5. Moffitt researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
6. Kinsey research: Postpartum women less stressed by threats unrelated to the baby
7. Family Counseling & Crisis Intervention Services in the US Industry Market Research Report from IBISWorld has Been Updated
8. Wayne State researcher finds possible clue to childrens early antisocial behavior
9. Pharmacy researcher finds most popular weight-loss drug strongly alters other drug therapies
10. Boston College researcher looks to stop a deadly parasite in its tracks
11. Survey shows breakthrough medical research relies heavily on NIH funding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... Newport Beach, CA (PRWEB) , ... May 23, 2017 , ... ... Capital Partners was honored to serve earlier this month as a Guest Speaker and ... by the British Royal Family and Common Purpose. , Walter Schindler ...
(Date:5/23/2017)... ... May 23, 2017 , ... By all indications, and due to months of ... call for diligence, asking homeowners to scout for any open water sources that can ... the annoying buzz of mosquitos is the buzz associated with potential infections stemming from ...
(Date:5/23/2017)... ... May 23, 2017 , ... ... provider in the modern ART laboratory, to provide hands-on training utilizing cutting-edge equipment ... , NextGen LifeLabs, a MedTech Group Purchasing vendor , will provide specialized ...
(Date:5/23/2017)... ... May 23, 2017 , ... New patients from Charleston, ... an experienced dentist practicing in Mt. Pleasant, SC, with or without a referral. A ... for patients with missing teeth in Charleston, SC. Those who suffer from ...
(Date:5/23/2017)... (PRWEB) , ... May 23, 2017 , ... New patients ... and chronic bad breath, can now receive laser gum disease treatments from the doctors ... Campbell and David Landau are raising awareness of the importance of receiving qualified treatment ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... Fix Inc. (" Fortuna "), a private, clinical-stage biotech ... need for embryonic and fetal stem cells by using direct ... Fortuna announced today the launch of its Scientific ... PhD; Father Kevin FitzGerald , S.J., PhD; Col. (R) ... Giordano , PhD. "We are excited and honored ...
(Date:5/4/2017)... 4, 2017  A new tight-tolerance microextrusion medical ... highly-engineered materials, is being launched by Natvar, a ... developed in recent years to service a wide ... applications. More expensive materials such as glass and ... due to their ability to consistently hold tolerances. ...
(Date:5/3/2017)... 2017  West Pharmaceutical Services, Inc. (NYSE: WST), ... drug administration, announced today that Fran DeGrazio ... and Diane Paskiet , Director, Scientific Affairs, ... on West,s expertise in the areas of safety ... providing commentary on updated industry guidance. ...
Breaking Medicine Technology: