Navigation Links
Research Takes Aim at Pancreatic Cancer
Date:4/18/2009

Discovery and testing in mice may lead to better detection and treatment

SATURDAY, April 18 (HealthDay News) -- An active receptor found in certain pancreatic cancers might offer hope for treatment of the often fatal disease.

A third of human pancreatic cancers looked at by Johns Hopkins University researchers contained a malfunctioning phosophorylated epidermal growth factor receptor (pEGFR), which previous studies had noted as being active in some lung cancers. When mice with this type of pancreatic cancer were given erlotinib, an EGFR-inhibitor drug approved for lung cancer treatment, the pancreatic tumors shrank, according to a news release from Experimental Biology 2009, a program of the American Society for Investigative Pathology.

Hopkins pathologist Dr. Akhilesh Pandey, who made the discovery, was expected to present the findings Saturday in New Orleans at the conference.

Although epidermal growth factor inhibitors had previously been tested as a pancreatic cancer treatment, Pandey and his team re-examined the studies and found that only one of 12 cancer samples tested contained the active pEGFR receptor.

The finding could lead to a biomarker detection tool for pancreatic cancer as well as a new treatment for these types of pancreatic cancers, Pandey said in the news release. His team is now reviewing scientific literature to compile a list of the proteins and genes known to be overexpressed in pancreatic cancers that should be considered future treatment targets.

More information

The American Cancer Society has more about pancreatic cancer.



-- Kevin McKeever



SOURCE: Federation of American Societies for Experimental Biology, news release, April
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Children of depressed moms do better when dad is involved, SLU researcher finds
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. New research shows how chronic stress worsens neurodegenerative disease course
6. New research explores newborn in-hospital weight loss
7. Research may unlock mystery of autisms origin in the brain
8. Bipolar disorder relapses halved by Melbourne researchers
9. HIVs impact in Zimbabwe explored in new research
10. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
11. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Research Takes Aim at Pancreatic Cancer
(Date:4/28/2015)... 2015 SeniorCare.com has published the ... reality problem Americans have regarding aging and long-term care ... care services as they age, 63% of Americans do ... In the report, Carol Marak of SeniorCare.com interviewed 44 ... Health Care Association and The Scan Foundation. The experts ...
(Date:4/28/2015)... FL (PRWEB) April 28, 2015 ... organization which provides vascular, electrocardiogram, echocardiogram, and NCV ... non-invasive vascular testing to help podiatrists diagnose peripheral ... challenging to diagnose PAD without the aid of ... Chief Medical Officer at Wimbledon Health Partners. ...
(Date:4/28/2015)... MO (PRWEB) April 28, 2015 The ... 2015 from 5:00 to 8:00 pm at the Sheraton Colonial ... than 50 hospitals, clinics and groups with career opportunities will ... represented. Attendees will enjoy free hors d’oeuvres and raffle prize ... PracticeMatch says “Boston is an ideal location to hold ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 The Awareness Counselor ... the common topic of judging. According to Awareness Counselor, there ... people, when directed outward, and to an individual who self-judges. ... new clients as a class or one one one talk. ... founder of Awareness Counselor, is that every being on earth ...
(Date:4/28/2015)... Aliso Viejo, CA (PRWEB) April 28, 2015 ... created for use in Final Cut Pro X ... attention to specific areas on-screen with classic buttons, animated ... Annotate is the perfect compliment to vlogs, video series, ... Cut Pro X 10.2 or newer. ProTube Annotate ...
Breaking Medicine News(10 mins):Health News:SeniorCare.com Report: America Has a Major Misconception on Aging 2Health News:Podiatrists Affiliate with Wimbledon Health Partners to Diagnose Peripheral Arterial Disease 2Health News:PracticeMatch to Host Physician Career Fair at Sheraton Colonial Boston North Hotel on May 6, 2015 2Health News:PracticeMatch to Host Physician Career Fair at Sheraton Colonial Boston North Hotel on May 6, 2015 3Health News:What Happens When We Judge Ourselves and Others? – A New Concept Introduced 2Health News:What Happens When We Judge Ourselves and Others? – A New Concept Introduced 3Health News:FCPX plugin developer Pixel Film Studios releases Protube Annotate plugin for Final Cut Pro X. 2
... A Dartmouth-led study of young U.S. teens showed that ... items featuring an alcohol brand, and those who do ... drinking from susceptibility, to beginning drinking, to binge drinking, ... Archives of Pediatrics & Adolescent Medicine . , ...
... study finds , , TUESDAY, March 3 (HealthDay News) -- The ... the worse his sex life, a new study finds. , ... bypass surgery can help reverse those ills. , "Previous studies ... and can be associated with infertility, but we wanted to ...
... long-term investment and social responsibility in industry categoryMADISON, N.J., ... DGX ), the world,s leading provider of diagnostic testing, ... magazine,s list of the World,s Most Admired Companies. Quest ... "Pharmacy and Other Services." The 2009 ranking is the ...
... long-term care insurance. , ... Newark, NJ (PRWEB) March 3, 2009 -- ... you off, Prudential has a way out the maze. Prudential ... confuse the decision-making process., , , , ,Although its design is simpler, ...
... of the World,s Most Admired CompaniesEL SEGUNDO, Calif., March ... care services, today accepted the honor by FORTUNE ... facilities in the country. DaVita(R) ranked #1 in the ... Investment and Quality of Products and Services. Overall, the ...
... LITTLE FALLS, N.J., March 3 Cantel Medical Corp. (NYSE: ... discuss the Company,s results for its second quarter ended January ... Participating in the call will be Charles M. Diker, ... President and CFO; and Roy K. Malkin, President of Minntech ...
Cached Medicine News:Health News:Owning alcohol-branded merchandise associated with teen drinking behaviors 2Health News:Men's Sex Lives May Suffer as Waistlines Expand 2Health News:Quest Diagnostics Again Named to FORTUNE Magazine's 'World's Most Admired Companies' List 2Health News:Prudential Long-Term Care Product Simplifies Decisions 2Health News:Prudential Long-Term Care Product Simplifies Decisions 3Health News:FORTUNE Magazine Ranks DaVita #1 Health Care Medical Facility in Innovation, Investment and Quality 2Health News:Cantel Medical Corp. to Hold Conference Call to Discuss Results for Its Second Quarter Ended January 31, 2009 2
(Date:4/27/2015)... , April 27, 2015 NxStage Medical, Inc. ... products, today announced that Jeffrey H. Burbank , Chief ... Care Conference in Boston, MA on ... A webcast of the event will be made available ... About NxStage NxStage Medical, Inc. ...
(Date:4/27/2015)...   Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ... for human disease, will release its first quarter 2015 ... financial markets close.  Lexicon management will hold a conference ... financial results for the first quarter 2015 at 5:00 ... The dial-in number for the conference call is 888-645-5785 ...
(Date:4/27/2015)... 27, 2015  CryoLife, Inc. (NYSE: CRY ), ... on cardiac and vascular surgery, announced today that it ... Food and Drug Administration ("FDA") verifying that the Company ... the warning letter it received from the FDA in ... re-inspection in March 2015 by the FDA at CryoLife,s ...
Breaking Medicine Technology:NxStage to Present at the 40th Annual Deutsche Bank Securities Health Care Conference 2Lexicon To Report First Quarter 2015 Financial Results On April 29, 2015 2CryoLife Announces Resolution of FDA Warning Letter 2
... the new screening guidelines announced by the National,Comprehensive Cancer ... will encourage those at high risk for lung cancer ... LCA President Laurie Fenton Ambrose said that lung ... all the other major cancers combined,until more at risk ...
... ILE ) announced today the completion of ... Study IT-A-008 investigating the Isolagen,Therapy(TM) for the treatment ... be administered at seven clinical sites across the ... Therapy could hold great promise for the,treatment of ...
Cached Medicine Technology:Lung Cancer Alliance Commends NCCN on Screening Guidelines 2Isolagen, Inc. Completes Enrollment in Isolagen Therapy(TM) Phase II/III Acne Scar Study 2Isolagen, Inc. Completes Enrollment in Isolagen Therapy(TM) Phase II/III Acne Scar Study 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: