Navigation Links
Research Brings New Hope to Multiple Sclerosis Patients
Date:2/18/2009

Aurora St. Luke's Medical Center Discovers Way to Fight Rare, but Deadly, Side Effect from Drug.

MILWAUKEE, Feb. 18 /PRNewswire/ -- Researchers at Aurora St. Luke's Medical Center have developed a technique that counteracts an unusual, but serious, side effect from natalizumab (Tysabri(R)), a drug that fights multiple sclerosis (MS).

The side effect is a brain virus called progressive multifocal leukoencephalopathy (PML).

"This virus looks like a multiple sclerosis relapse," Dr. Bhupendra Khatri says. "It rapidly destroys the white matter of the brain. Now we know exactly how to respond if this virus emerges."

The response is a series of plasma exchanges that filter the drug out of the blood stream, allowing the immune system to recover and fight the virus.

Multiple sclerosis is a disease where the body's immune system attacks the protective sheath surrounding the nerves. Natalizumab suppresses the immune system to slow or halt the progression of the disease. However, if the patient contracts PML, the immune system is not strong enough to combat the infection, so the drug needs to be removed from the body quickly.

Dr. Khatri, medical director of Aurora's Regional MS Center is lead author of the study published in the Feb. 3 issue of Neurology, the official publication of the American Academy of Neurology.

In the study 12 multiple sclerosis patients on natalizumab underwent three plasma exchange sessions over a five-day or an eight-day period. By replacing the drug-infused plasma with clean fluid, Dr. Khatri and his team were able to get 92 percent of the drug out of patients' bodies over a span of eight days instead of the 12 weeks it would take with no treatment.

Debra Goodwin, a clinical research nurse who worked on the study and a multiple sclerosis patient herself, says the discovery gives new hope to those with the disease who take natalizumab.

"If something were to go wrong, now there is a demonstrated method to remove the drug from the body and help the patient fight PML," Goodwin says.

The National Multiple Sclerosis Society estimates 400,000 people in the United States have MS. There is no cure for multiple sclerosis though there are several drugs that can slow or stop its progress. Symptoms can include blurred vision, loss of coordination and short-term or long-term memory loss.

Aurora Health Care is a not-for-profit health care provider and a national leader in efforts to improve the quality of health care. Aurora offers care at sites in more than 90 communities throughout eastern Wisconsin.

Aurora's online newsroom: http://www.aurora.org/newsroom

The Regional MS Center: www.aurora.org/MS


'/>"/>
SOURCE Aurora St. Luke's Medical Center
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Study calls for increased research in flu transmission to prepare for pandemic flu outbreak
2. Research increases possibilities of personalizing treatment of infant osteosarcoma
3. Two Scientists Honored with MetLife Foundation Awards for Medical Research in Alzheimers Disease
4. The Canadian Foundation for Global Health Announces a Research and Development Partnership with Medizone International, Inc.
5. Apple's iPod Touch Joins the iPhone as a Stuttering Therapy Tool At Hollins Communications Research Institute
6. Rice Universitys Baker Institute experts available to discuss stem cell research, recommendations
7. eResearchTechnology, Inc. to Announce Fourth Quarter and Full Year 2008 Results on February 26, 2009
8. National Pharmaceutical Council on Economic Stimulus Package: Comparative Effectiveness Research Funding Should Target Improvements in Quality of Patient Care
9. OHSU vaccine research targets HIV in the slower, early stage of infection
10. American Association for Cancer Research lauds Senator Arlen Specter
11. In flurry of studies, researcher details role of apples in inhibiting breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... ... , ... Sideline Products is a Southern York County Pennsylvania-based premier designer and ... the horse. Smaller saddles can pinch and irritate the horse creating safety issues and ... fitted western saddle so it does not impact the comfort or performance of the ...
(Date:12/5/2016)... ... December 05, 2016 , ... Airy Jeanine ... with prolific Songwriter-Producer Corey “Chorus” Gibson who has worked on hits by mega-artists ... a few.     https://twitter.com/coreychorus , The sessions taking place in North Jersey’s ...
(Date:12/5/2016)... ... , ... As renowned, board-certified dermatologists, Dr. Sabrina G. Fabi and Dr. Douglas ... not do their research and undergo cosmetic dermatology treatments from unqualified practitioners or worse, ... renaissance and every other month a new treatment or device is launched, promising everlasting ...
(Date:12/5/2016)... Columbus, OH (PRWEB) , ... December 05, 2016 ... ... novel engineering solution called the CardioQuick Patch® significantly improves the reproducibility and accuracy ... usability in various healthcare settings. , Over the last 60 years, studies ...
(Date:12/4/2016)... , ... December 03, 2016 , ... While James Earl ... serving as host for in a show called "Front Page". One of the forthcoming ... years, breast cancer rates have plummeted in large part due to early detection. Like ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Dec. 5, 2016  New research by the ... Institute and the U.S. Department of Health and ... Preparedness and Response (ASPR), published online today in ... pharmacy notifications encourage patients with chronic conditions to ... The study also affirms that public-private partnerships can ...
(Date:12/5/2016)... Dec. 5, 2016  BD (Becton, Dickinson and Company) ... technology company, will demonstrate an enhanced technology platform designed ... including the company,s leading Pyxis™ and Alaris™ systems, at ... 2016 Midyear Meeting being held in ... While national data show that approximately 68 percent of ...
(Date:12/5/2016)... 5, 2016 Research and Markets has announced the ... Forecast to 2021" report to their offering. ... , , The global ... by 2021, at a CAGR of 5.3% from 2016 to 2021. Factors ... obesity cases, increasing government spending on healthcare, and rising income levels are ...
Breaking Medicine Technology: