Navigation Links
Rare Gene Mutation Plays Role in Longevity
Date:3/4/2008

Study found it restricts growth factor, leads to shorter stature but longer life

TUESDAY, March 4 (HealthDay News) -- A rare gene mutation that restricts a particular growth factor may be one of the keys to living to 100 and beyond, a new study suggests.

This mutation, which seems to decrease the activity of insulin-like growth factor (IGF-1), results in short stature but longer life. Exactly why this might lengthen someone's life isn't known, but the researchers say the finding might prove useful in developing anti-aging drugs.

"We found that people of a hundred years old have mutations in a gene that is related to the growth hormone pathway," said lead researcher Dr. Nir Barzilai, director of the Institute for Aging Research at the Albert Einstein College of Medicine in New York City. "We think this is important, because that's what now happens in nature. The pony lives longer than the horse, the small dog lives longer than a large dog. Apparently, it's true for humans also."

Interestingly, this particular mutation has been found mostly among women, he added.

It might be possible, given these findings, to develop drugs that can prevent aging and age-related disease, Barzilai noted. "There are drugs being developed to decrease growth hormone in patients with tumors, because sometimes cancer is dependent on growth hormones," he said. "Maybe we can adopt the strategy to slow aging."

The report was published in this week's online issue of the Proceedings of the National Academy of Sciences.

In the study, Barzilai's team looked for this mutation among a population of Ashkenazi Jews who were 100, and their offspring. They also matched these offspring with people who had no history of longevity in their family. The researchers found this particular mutation was more common among those who were centenarians and their offspring. The same research team reported in December 2006 that a p
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Einstein researchers discover gene mutations linked to longer lifespans
2. Genetic mutation found in peripheral artery disease
3. 2 Mutations Were Critical to Spread of 1918 Flu
4. Single Mutation in Mitochondrial DNA Weakens Heart, Muscles
5. Benefit of cancer prevention surgery differs between women with BRCA1 and BRCA2 mutations
6. BRCA1 mutation linked to breast cancer stem cells
7. Scientists explore factors contributing to DNA mutations
8. Scripps research scientists find new genetic mutation that halts the development of lupus
9. Genetic Mutations Boost Prostate Cancer Risk
10. BRCA Mutations Dont Raise Breast Cancer Risk Equally
11. Ashkenazi ovarian cancer patients with BRCA mutations live longer than those with normal gene
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rare Gene Mutation Plays Role in Longevity
(Date:5/27/2015)... (PRWEB) May 27, 2015 SAN ... in Gulfport Mississippi, is the first healthcare provider ... approach to chronic care management (CCM). In partnership ... Memorial is introducing RevUp, a new program that ... requirements and increase monthly reimbursements. This new, user-friendly ...
(Date:5/27/2015)... HOUSTON, Tx (PRWEB) May 27, 2015 ... combined germline pharmacogenomic and somatic genomic analysis in personalized ... was published by the American Society of Clinical Oncology ... – June 2 in Chicago. , The molecular and ... The Cancer Genome Atlas (TCGA) database. The study reports ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 On June ... advertising agency, will partner with LifeSource to host Donate ... will take place in a LifeSource donor coach outside ... to 4:00 p.m. , Demand for whole blood units ... Illinois, during the summer months. LifeSource requires approximately 1,000 ...
(Date:5/27/2015)... Texas (PRWEB) May 27, 2015 ... the current state of the Omega-3 industry. The ... including definitions, classifications, applications and industry chain structure. ... international markets including development trends, competitive landscape analysis, ... Gc Rieber Oils, Camanchaca Fishing Company, Seadragon Marine ...
(Date:5/27/2015)... May 27, 2015 SonarMD, ... SonarMD Platform, a first-of-its kind, cloud-based algorithmic ... patients with chronic gastrointestinal disease. , Developed ... the application allows physicians to monitor their ... ongoing use of electronic health assessment surveys. ...
Breaking Medicine News(10 mins):Health News:Memorial Hospital Selects MD Revolution's Digital Health Platform to Deliver a New Form of Chronic Care Management 2Health News:Memorial Hospital Selects MD Revolution's Digital Health Platform to Deliver a New Form of Chronic Care Management 3Health News:CompanionDx® Analyzes Non-small Cell Lung Cancer Data for Personalized Cancer Therapy 2Health News:CompanionDx® Analyzes Non-small Cell Lung Cancer Data for Personalized Cancer Therapy 3Health News:Donate Your Break and Save Lives at the River North Blood Drive 2Health News:Omega-3 Market: Global 2015 Analysis & 2020 Forecasts on Market Size 2Health News:SonarMD™, LLC, Launches Game-Changing, IBD Population Health Management Platform 2
... A new vaccine called the TAT vaccine has been developed ... to date. And more importantly it has had a 71% ... ready for human testing and this may be the brightest ... Head of the Department of Virology at Italy’s National Health ...
... Allergy and asthma patients can now breathe easy. Literally. A ... be effective in improving the quality of life and has ... findings of this study are reported in the latest issue ... M. Walker, PhD, of the Imperial College School of Medicine ...
... been used to test the importance of sleep for ... of side effects, such as fatigue and reduced alertness. ... circumventing these complications by allowing recovery sleep by Harvard ... the first day showed no improvement in task performance ...
... so aggressive and almost impossible to handle at times? Then read ... the children of today are growing up. Even the West is ... India. With the TV boom and the IT revolution, the kids ... parents complain that their kids are actually going over the edge, ...
... at the just concluded Indian science congress in New Delhi ... combat anemia with iron fortification of crops. Almost 50% of ... anemic in India. While iron supplementation is expensive, fortification of ... anemia in people is fairly cheaper, scientists say. ,This ...
... to increased risk of heart problems to their children ... several aspects of cardiovascular risks in adult life, but ... mothers starved during the first 13 weeks of pregnancy ... Starvation during mid or late pregnancy don’t have a ...
Cached Medicine News:
(Date:5/27/2015)... BUENA, N.J. , May 27, 2015  IGI ... Jersey -based specialty generic pharmaceutical company, today updated ... Second Quarter and Full Year 2015 Updated ... three months ended June 30, 2015 are still expected ... sequential improvement quarter over quarter in total revenue for ...
(Date:5/27/2015)... ZIONA, Israel , May 27, 2015 /PRNewswire/ ... Capital has led an investment round of $10 million in ... participation by the company,s chairman and CEO Mr. Ehud ... company,s clinical development plans; the funding is sufficient to advance ... once every four weeks injection, currently at Phase II, up ...
(Date:5/27/2015)... , 27. Mai 2015 Experten ... GERD) diskutierten im Rahmen einer Spezialpräsentation auf ... Erfahrungen mit der Stretta-Therapie für ... Patientengruppen. Infografik - ... , MD, von der Case Western Reserve ...
Breaking Medicine Technology:IGI Laboratories Updates Business Outlook 2IGI Laboratories Updates Business Outlook 3Mapi Pharma Closes $10 Million Investment Led by Shavit Capital 2DDW-Präsentation untersucht die vielseitige und wirkungsvolle Behandlung von GERD durch Stretta in multiplen Patientengruppen 2DDW-Präsentation untersucht die vielseitige und wirkungsvolle Behandlung von GERD durch Stretta in multiplen Patientengruppen 3DDW-Präsentation untersucht die vielseitige und wirkungsvolle Behandlung von GERD durch Stretta in multiplen Patientengruppen 4
... Sigma-Aldrich (Nasdaq: SIAL ) announced today that it ... leader in bench top flow chemistry instruments, the terms ... of approximately 400 CatCart® catalyst products for flow chemistry ... and CatCart catalyst cartridges provide organic chemists in academic ...
... Accumetrics, Inc., developer and marketer of the VerifyNow® ... measuring an individual,s response to multiple antiplatelet agents, announced ... that will raise $16.5 million in new capital. ... into 2011, came from the company,s existing investors, including ...
Cached Medicine Technology:Sigma-Aldrich(R) Partners With Flow Chemistry Leader ThalesNano to Provide CatCart(R) Catalyst Products for Rapidly Growing Market 2Sigma-Aldrich(R) Partners With Flow Chemistry Leader ThalesNano to Provide CatCart(R) Catalyst Products for Rapidly Growing Market 3Accumetrics Announces $16.5M in New Capital Financing 2Accumetrics Announces $16.5M in New Capital Financing 3
Sample throughput of up to 80 tests per hour (4 modules). Low maintenance requirements. Continuous random access. 25 - 100 channels on board. 1008 tests or 6 hours of walkaway operation....
The Embla 384 cell washer is a top-loading, robotic-compatible microplate washer for high throughput screening. It is designed specifically for cell-based assays, which require a gentler wash, but ca...
Elisa Plate Reader...
The Benchmark Microplate Reader, with its increased wavelength range of 340 to 750 nm and high performance optics, provides flexibility for specialized applications requiring increased linearity, ult...
Medicine Products: