Navigation Links
Quality control mechanism tags defective sperm cells inside the body
Date:1/23/2008

COLUMBIA, Mo. Defective sperm cells do not pass through the body unnoticed. A new University of Missouri study provides evidence that the body recognizes and tags defective sperm cells while they undergo maturation in the epididymis, a sperm storage gland attached to the testis. According to researchers, only the best sperm that have the highest chance of succeeding in fertilization will survive the production process without a tag.

A small protein called ubiquitin marks abnormal sperm cells, including cells that have two heads, two tails or are otherwise misshaped. This recycling tag on the sperm cell tells the body which cells need to be broken back down into amino acids. This provides evidence that there is an active removal process or marking of defective sperm during the epididymal passage.

Fertilization is, in a way, a numbers game, said Peter Sutovsky, associate professor of animal sciences, clinical obstetrics and gynecology in the MU College of Agriculture, Food and Natural Resources. You need a certain number of normal sperm cells to reach the egg. If too many are tagged with ubiquitin, there may be not enough to fertilize an egg.

This study suggests that the male reproductive system must be able to evaluate and control the quality of the sperm to insure an optimal chance of fertilization. High levels of ubiquitin in the sperm can indicate low-sperm count or infertility. This process of quality control has been found in both humans and other mammals including bulls, boars and rats.

In many cases, the cells that are tagged with ubiquitin are obviously abnormal with two tails or two heads, but many of them look like they dont have defects, Sutovsky said. Oftentimes, these cells may look normal but lack proteins that are important to fertility.

Once sperm cells are tagged as defective, it is unlikely that the process can be reversed. Sutovsky stresses the importance of a healthy lifestyle to reduce the
'/>"/>

Contact: Jennifer Faddis
FaddisJ@missouri.edu
573-882-6217
University of Missouri-Columbia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Governor Rendell Offers Coverage to 29,000 on AdultBasic Waiting List; Unveils New Policy to Improve Quality of Care for the Low-Income and Pennsylvanians With Disabilities
2. National Business Coalition on Health Awards Grants to 14 Coalitions for Diabetes Quality Programs
3. States Patient Safety Report a Valuable Tool For Hospitals Quality Improvement Work
4. Virginia Cares Uninsured Program (VCUP) Announces Early Successes in Helping Uninsured Virginians Access Quality Healthcare
5. Anyone can save a life: Penn researchers lead national efforts to improve CPR quality
6. Heavy metal slips down UK air quality charts
7. Integrating Quality into Business Systems for High Performance, Complimentary Excerpt Available from Best Practices, LLC
8. Michigan Quality Council (MQC) Names Oakwood Healthcare Inc. 2007 State Quality Award Recipient
9. Tonsillectomy significantly improves quality of life in adult and pediatric patients
10. Michigan Quality Council (MQC) Names Henry Ford Health System 2007 State Quality Award Recipient
11. New Web Site Opens Window on Charges, Payments, Quality of Care at Michigan Hospitals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... (PRWEB) December 19, 2014 From November 24, ... teacher training for the year 2014 in its Goa ... this year. Through the Indian winters, from November to March, ... the beautiful beach of Arambol, Goa. The Goa training sessions ... previous intakes of yoga teacher training, the 10th intake is ...
(Date:12/19/2014)... Dallas, TX (PRWEB) December 19, 2014 ... current state of the global Gliquidone industry with a ... statistics on the market status of the Gliquidone manufacturers ... for companies and individuals interested in the industry. , ... industry including its definition, applications and manufacturing technology. Then, ...
(Date:12/19/2014)... 18, 2014 (HealthDay News) -- Being in good shape seems ... They looked at data from more than 57,000 Americans, ... treadmill tests between 1991 and 2009. Those in the ... having high blood pressure at the start of the study, ... levels of fitness. Of the more than 8,000 people ...
(Date:12/19/2014)... HealthDay Reporter THURSDAY, Dec. 18, ... exposed to high levels of air pollution late in pregnancy ... study suggests. Researchers found that of nearly 1,800 U.S. ... to the most air pollution during pregnancy were twice as ... exposure during the third trimester, specifically, showed the strongest correlation ...
(Date:12/19/2014)... News) -- Prostaglandin analogue eye drops -- a common ... of vision loss in patients with the eye disease, ... David Garway-Heath, of the Moorfields Eye Hospital and UCL ... than 500 people newly diagnosed with open-angle glaucoma -- ... of the leading causes of blindness. About 45 ...
Breaking Medicine News(10 mins):Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 2Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 2Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 4Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 5Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 6Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 2Health News:Smog Exposure During Pregnancy Linked to Autism Risk 3Health News:Study Supports Benefit of Widely Used Glaucoma Drug 2
... uncertainty about risks and benefits of mastectomies or lumpectomies. ... the women diagnosed with early-stage breast cancer clearly understand ... breast-conserving lumpectomy plus radiation, even after they have one ... If the woman is black or Hispanic, the chances ...
... CNS Response,Inc. (OTC Bulletin Board: CNSO) ... roll out referenced-EEG(R) (rEEG(R)) availability with an,undisclosed, ... enables psychiatrists under the management of the ... to treat their most,therapy-challenged patients suffering any ...
... LCA-Vision Inc. (Nasdaq:,LCAV), a leading provider of ... the opening of its 76th LasikPlus(R) vision,center in ... vision center opened this year, and the second ... a LasikPlus(R) vision,center in Paramus in April 2006., ...
... surgeons precise fingertip power control during laparoscopic procedures while, ... first in ... the healthcare industry, BOULDER, ... unique opportunity to offer surgeons greater control,and precision during surgeries ...
... 31 Ingenuity Systems, the,leading provider of ... that Path Designer, the new pathway publishing ... Best New Product by the scientific community ... San Francisco. Path,Designer enables researchers to create ...
... the United States face strikingly high levels of stigma, according ... AIDS Research. , The amfAR survey results will be ... 9 a.m. at the National Press Clubs 13th Floor First ... The press conference will be followed by a briefing in ...
Cached Medicine News:Health News:Many Women Unclear About Breast Cancer Treatments 2Health News:CNS Response, Inc. Enters Agreement to Introduce rEEG(R) Platform to Managed Behavioral Health Organization 2Health News:CNS Response, Inc. Enters Agreement to Introduce rEEG(R) Platform to Managed Behavioral Health Organization 3Health News:CNS Response, Inc. Enters Agreement to Introduce rEEG(R) Platform to Managed Behavioral Health Organization 4Health News:LCA-Vision Announces the Opening of its 76th LasikPlus(R) Vision Center in Woodbridge, New Jersey 2Health News:Encision Moves Power and Safety to Surgeons' Fingertips 2Health News:Ingenuity's Path Designer is Selected as Best New Product by Life Science Community at 2008 Molecular Medicine Conference 2Health News:Ingenuity's Path Designer is Selected as Best New Product by Life Science Community at 2008 Molecular Medicine Conference 3Health News:Stigma clings stubbornly to women living with HIV/AIDS 2Health News:Stigma clings stubbornly to women living with HIV/AIDS 3
(Date:12/19/2014)... CARDIFF-BY-THE-SEA, Calif. , Dec. 19, 2014 ... ;  Sorrento), an oncology company developing new treatments ... a privately-held immuno-oncology company developing proprietary Neukoplast ® ... therapy, announced today that the companies have entered ... generation CAR-TNK™ (pronounced as "Car-Tank") immunotherapies for the ...
(Date:12/19/2014)... 18, 2014 Research and Markets ... the "Micro Market Monitor: North American Dermatology ... http://photos.prnewswire.com/prnh/20130307/600769 ... steadily, which has resulted in fueling the overall ... main purpose of these dermatology devices is to ...
(Date:12/19/2014)... CITY, Calif., Dec. 18, 2014 Capnia, ... the development of medical diagnostics based on its ... gas flow, today announced financial results for the ... 2014. "Following the completion of our ... positioned to maximize the recently initiated CoSense® commercial ...
Breaking Medicine Technology:Sorrento and Conkwest Announce Exclusive Global Collaboration 2Sorrento and Conkwest Announce Exclusive Global Collaboration 3Sorrento and Conkwest Announce Exclusive Global Collaboration 4Sorrento and Conkwest Announce Exclusive Global Collaboration 5Micro Market Monitor: North American Dermatology Diagnostic Devices Market 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 3Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8
FlexiSlip™ Plastic coated malleable metal core. Single use, Sterile, Latex Free. Soft distal tip flexes to reduce risk of trauma to patient. Malleable metal core is easy to shape. Low friction ...
Surgical Stainless Steel Child Stylette....
Surgical Stainless Steel Adult 16.5....
Ultra-Slip™ endotracheal tube guide for single-patient use only., ,Caution: Not MRI Compatible....
Medicine Products: