Navigation Links
Prescription problems for vets on reflux drug
Date:2/20/2013

CHICAGO --- U.S. veterans diagnosed with gastroesophageal reflux disease (GERD) are frequently prescribed doses of proton pump inhibitors (PPIs), such as omeprazole (commonly known by brand names such as Prilosec), that are much higher than recommended --- and they are kept on the drug far too long, according to a new Northwestern Medicine study.

PPIs are among the most widely used drugs in the nation, resulting in more than $11 billion in annual direct health care costs in the U.S. PPI overuse has been documented in previous studies, but this is the first study to examine initial prescriptions given to veterans with a new GERD diagnosis.

"We should always have a reevaluation after an initial prescription and ask, 'Does this patient need to be on this medication?'" said Andrew Gawron, M.D., first author of the study and a fellow in the division of gastroenterology and the Center for Healthcare Studies at Northwestern University Feinberg School of Medicine. "Proton pump inhibitors are provided ubiquitously in medicine, and although they provide relief for many patients, optimal prescribing is important to avoid prolonged, unnecessary use and cost."

Sherri LaVela, research assistant professor at Feinberg's Center for Healthcare Studies and a research health scientist at the Edward Hines, Jr. VA Hospital in Hines, IL, is Gawron's mentor and the senior author of the study, which was published Feb. 16 in the Journal of General Internal Medicine.

The researchers evaluated more than 1,600 Veterans at the Hines VA from 2003 to 2009. Here are the major findings, which highlight the potential problems:

  • The majority of patients received more than a three-month initial supply of medication.
  • Almost 25 percent of patients were given high total daily dose prescriptions.
  • Very few patients who started on high dose therapy had reductions in dosing more than two years after their initial prescription.

It is recommended that PPIs be prescribed at the lowest effective dose for four to eight weeks to treat GERD. If symptoms persist after eight weeks, efforts should be made to evaluate other potential causes of symptoms and alternative approaches to therapy. This approach is a top priority in the "Choosing Wisely" campaign initiated last year by the American Board of Internal Medicine and the American Gastroenterology Association.

"It seems that once these veterans are prescribed a PPI, they are rarely taken off of it," Gawron said. "Two years after their initial prescription, most are still on the drug."

This study highlights the importance of ensuring appropriate use of PPIs in all patients after they are initially prescribed, Gawron said.


'/>"/>

Contact: Erin White
ewhite@northwestern.edu
847-491-4888
Northwestern University
Source:Eurekalert

Related medicine news :

1. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
2. Many Who First Misuse Prescription Pills Get Them From Friends, Family: Report
3. 16 years old is peak risk for teens misusing prescription drugs
4. Mental Health Woes Raise Odds for Prescription Painkiller Abuse
5. American Kids Getting Fewer Prescription Drugs: Study
6. More Mental Health Woes in College Kids Who Abuse Prescription Drugs
7. Herpes Treatment Site: Top Reasons to Avoid Prescription HSV Drugs
8. Changes needed for oft-ignored prescription warning labels
9. AFTS Labs Partners With Physicians To Complement NY's Mandated I-STOP Tracking System For Pain Pill Prescriptions: A Recipe For A Safer Community
10. Good mood foods: Some flavors in some foods resemble a prescription mood stabilizer
11. PharmaNet system dramatically reduced inappropriate prescriptions of potentially addictive drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced ... attorneys chosen by their peers for this recognition are considered among the top 2 ... received special honors as members of this year’s Legal Elite Hall of Fame: ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
(Date:6/24/2016)... ... 24, 2016 , ... Strategic Capital Partners, LLC (SCP) in ... investment capital for emerging technology companies. SCP has delivered investment events and ... more than a million dollars of capital investment for five companies. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June 24, 2016 ... mobile pulmonary function testing company, is now able to perform sophisticated ... by ndd Medical Technologies , Inc. Patients ... hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients ... get any needed testing done in the comfort of her own ...
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
Breaking Medicine Technology: