Navigation Links
Prescription problems for vets on reflux drug
Date:2/20/2013

CHICAGO --- U.S. veterans diagnosed with gastroesophageal reflux disease (GERD) are frequently prescribed doses of proton pump inhibitors (PPIs), such as omeprazole (commonly known by brand names such as Prilosec), that are much higher than recommended --- and they are kept on the drug far too long, according to a new Northwestern Medicine study.

PPIs are among the most widely used drugs in the nation, resulting in more than $11 billion in annual direct health care costs in the U.S. PPI overuse has been documented in previous studies, but this is the first study to examine initial prescriptions given to veterans with a new GERD diagnosis.

"We should always have a reevaluation after an initial prescription and ask, 'Does this patient need to be on this medication?'" said Andrew Gawron, M.D., first author of the study and a fellow in the division of gastroenterology and the Center for Healthcare Studies at Northwestern University Feinberg School of Medicine. "Proton pump inhibitors are provided ubiquitously in medicine, and although they provide relief for many patients, optimal prescribing is important to avoid prolonged, unnecessary use and cost."

Sherri LaVela, research assistant professor at Feinberg's Center for Healthcare Studies and a research health scientist at the Edward Hines, Jr. VA Hospital in Hines, IL, is Gawron's mentor and the senior author of the study, which was published Feb. 16 in the Journal of General Internal Medicine.

The researchers evaluated more than 1,600 Veterans at the Hines VA from 2003 to 2009. Here are the major findings, which highlight the potential problems:

  • The majority of patients received more than a three-month initial supply of medication.
  • Almost 25 percent of patients were given high total daily dose prescriptions.
  • Very few patients who started on high dose therapy had reductions in dosing more than two years after their initial prescription.

It is recommended that PPIs be prescribed at the lowest effective dose for four to eight weeks to treat GERD. If symptoms persist after eight weeks, efforts should be made to evaluate other potential causes of symptoms and alternative approaches to therapy. This approach is a top priority in the "Choosing Wisely" campaign initiated last year by the American Board of Internal Medicine and the American Gastroenterology Association.

"It seems that once these veterans are prescribed a PPI, they are rarely taken off of it," Gawron said. "Two years after their initial prescription, most are still on the drug."

This study highlights the importance of ensuring appropriate use of PPIs in all patients after they are initially prescribed, Gawron said.


'/>"/>

Contact: Erin White
ewhite@northwestern.edu
847-491-4888
Northwestern University
Source:Eurekalert

Related medicine news :

1. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
2. Many Who First Misuse Prescription Pills Get Them From Friends, Family: Report
3. 16 years old is peak risk for teens misusing prescription drugs
4. Mental Health Woes Raise Odds for Prescription Painkiller Abuse
5. American Kids Getting Fewer Prescription Drugs: Study
6. More Mental Health Woes in College Kids Who Abuse Prescription Drugs
7. Herpes Treatment Site: Top Reasons to Avoid Prescription HSV Drugs
8. Changes needed for oft-ignored prescription warning labels
9. AFTS Labs Partners With Physicians To Complement NY's Mandated I-STOP Tracking System For Pain Pill Prescriptions: A Recipe For A Safer Community
10. Good mood foods: Some flavors in some foods resemble a prescription mood stabilizer
11. PharmaNet system dramatically reduced inappropriate prescriptions of potentially addictive drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... , ... February 26, 2017 , ... ... 2011 the lab became the world’s first to be ISO/IEC 17025:2005 INAB accredited ... allergen) analysis. , ISO/IEC 17025:2005 is the globally recognised standard that sets out ...
(Date:2/26/2017)... York (PRWEB) , ... February 26, 2017 , ... ... products for wholesale distribution in North America, today announced it would be offering ... The company, which prides itself on crafting quality and unique baby clothing/feeding products, ...
(Date:2/26/2017)... Park, KS (PRWEB) , ... ... ... of StaffBridge sets a new technology standard in staffing, scheduling, and reporting ... manage, monitor, and predict activity throughout the entire staffing process. StaffBridge technology ...
(Date:2/26/2017)... (PRWEB) , ... February 26, 2017 , ... ... patients after receiving cognitive rehabilitation, according to a study released today at the ... that cognitive rehabilitation programs are proven to be effective in improving cognitive function ...
(Date:2/25/2017)... ... February 25, 2017 , ... FCPX users now have the ... Pixel Film Studios. With ProSharpen Color users have total control over sharpening amount, sharpening ... color range. With color spectrum tools users can visually see the color range effected ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... -- Leading Countries, Technologies and Companies ... at a CAGR of 8.9% from 2016-2021 and CAGR of 9.2% ... of 9.1% from 2016 to 2027. The market is estimated at ... ... Read on to discover how you can exploit the future business ...
(Date:2/27/2017)... Feb 27, 2017 The Dutch ... NATO for use at the security level RESTRICTED. The solution ... NATO organization for the communication of classified information. ... Sectra and Samsung ... an eavesdrop-secure smartphone solution. Sectra Tiger/R is developed by Sectra ...
(Date:2/24/2017)... Feb. 24, 2017 Zimmer Biomet Holdings, Inc. ... healthcare, will present at the Cowen and Company 37 ... Marriott Copley Place on Tuesday, March 7, 2017 at ... webcast of the presentation can be accessed at ... following the conference via Zimmer Biomet,s Investor Relations website ...
Breaking Medicine Technology: