Navigation Links
Other stomach microbiota modulate resistance to H. pylori-driven ulcers
Date:3/25/2013

WASHINGTON, DC March 25, 2013 Mice with different naturally occurring stomach bacteria have distinct susceptibilities to disease caused by Helicobacter pylori, the well-known cause of ulcers in humans, according to a study published online ahead of print in the journal Infection and Immunity. This is the first study to document (in mice) that the presence of certain bacteria in the stomach microbiota can prevent pathology from H. pylori.

The gastro-intestinal tract is a veritable ecosystem packed with microbes, and over the last decade, investigators have been discovering that the species composition of that ecosystem can have a profound effect on human health. But the eureka moment that led to this study came "when we realized that mice from different vendors mount different responses to H. pylori infection," says principal investigator Karen Ottemann of the University of California, Santa Cruz.

Following this discovery, the researchers divided mice from the vendor, Taconic Farms, into three groups: mice treated with antibiotics in order to kill some of the resident bacteria, mice that were fed normal stomach bacteria after antibiotic treatment, and mice that were not treated. They then infected each group with H. pylori, and assayed the animals' stomachs for immune system cells.

"The antibiotic-treated mice had small quantities of particular inflammatory cells, called Th1 T helper cells," says Ottemann. Both the untreated mice, and the treated mice that were then fed normal stomach bacteria had normal (higher) levels of Th1 T helper cells. These results suggested that the normal stomach microbes contribute to disease caused by H. pylori, says Ottemann.

The researchers then determined that around 4,000 species of bacteria were different in the high- and low-inflammation (no antibiotics, and antibiotic-treated, respectively) mice. Notably, the mice with low inflammation "had ele
'/>"/>

Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New insights into when beach sand may become unsafe for digging and other contact
2. Chemotherapy proves life-saving for some leukemia patients who fail induction therapy
3. Immunotherapy for elderly cancer patients finds new promise in drug combination
4. Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients
5. Concerns about MRSA for expectant mothers may be unfounded
6. Another Drug Take-Back Day Scheduled for Saturday
7. Low-Income Mothers May Overfeed Their Infants
8. New global report says US lags behind 130 other nations in preterm birth rate
9. Screening for Other Health Problems May Aid COPD Survival
10. Stem cell sparing radiotherapy for head and neck cancer may avoid salivary gland damage
11. Genetic predictor of breast cancer response to chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... 31, 2014 Hoping to attract new customers ... trust , NutriGold is ready to ship out free ... make taking advantage of this offer fast and easy: ... and Development at NutriGold, "We know that every time customers ... their most precious asset: their own health or the health ...
(Date:7/31/2014)... TN (PRWEB) July 31, 2014 In many ... are required for proper storage of necessary life saving drugs. ... staff. Unfortunately there is still a high number of ambulances ... an EMT who steals the narcotics and even replaces the ... relief receives none. As seen in the case in Baraboo, ...
(Date:7/31/2014)... Niche Profit Classroom, a method and guide ... to provide a blueprint for anyone who is interested in ... prompting an investigative review. , Learn more about ... about the success of the information in this course is ... have stayed effective even through all of the major search ...
(Date:7/31/2014)... United Theological Seminary is pleased to welcome ... and Peter J. Bellini. Both began their teaching duties ... a Director of Non-Degree Programs, Mark Abbott, who begins ... Donne, Assistant Professor of New Testament, received a Ph.D. ... Second Temple Judaism, and Greek courses. His research interests ...
(Date:7/31/2014)... Angeles, CA (PRWEB) July 31, 2014 US ... his practice will now be known as Parsa Mohebi Hair ... has helped hundreds of patients in Southern California and around ... Los Angeles, Beverly Hills and Orange County. These patients achieved ... including many surgical techniques that were perfected by Dr. Mohebi. ...
Breaking Medicine News(10 mins):Health News:NutriGold Launches Product Samples Page for its Supplements 2Health News:NutriGold Launches Product Samples Page for its Supplements 3Health News:New MedixSafe Alert - Ambulances Must Have A Medical Safe, Narcotics Cabinet, or Drug Locker 2Health News:Niche Profit Classroom: Review Exposes Adam Short’s Guide to Building Niche Websites 2Health News:Growing Seminary Welcomes New Faculty 2Health News:US Hair Restoration Becomes Parsa Mohebi Hair Restoration 2
... Today the International and American Associations for Dental Research ... remains the number one journal of 64 journal published in ... new 2009 Five-Year Scientific Impact Factor (SIF) rankings, published by ... the JDR,s Five-Year SIF increased from 3.966 to 4.195. ...
... , ... open to the public, Andy Thomas job seminars teach participants unique personal marketing strategies ... Minutes to a Better Career”; Career counselor Thomas is a former talk show host ... 60 unemployed in attendance, and a drawing will be held for Thomas providing free ...
... DocGreet.com is ... their time and streamline their patient communication, that the company has announced a money back ... ... sure that the services available to Doctors, Physicians and Health Care Providers will monetize their ...
... ... of the Enterprise Architecture Professional Practice Guide and a brochure on Enterprise Architecture as a ... (PRWEB) June ... ,These abstracts provide the enterprise architect,s contract with the public they serve and consist of ...
... colonoscopy is effective and cost-effective when targeted to ... Gastroenterology , the official journal of the ... surveillance colonoscopy could be excessively costly or even ... and utilized practice that has the potential to ...
... Institute (NHLBI), part of the National Institutes of Health, is ... efficacy of red blood cell transfusions vary depending on how ... supports the first large, multi-center, randomized clinical trial to compare ... blood cells that have been stored for shorter or longer ...
Cached Medicine News:Health News:JDR increases its 5-Year SIF and remains number one dental journal of 64 in its category 2Health News:Columbia Extreme Job Makeover Slated for June 26 2Health News:Columbia Extreme Job Makeover Slated for June 26 3Health News:DocGreet Guarantees More Time and Money to Doctors and Health Care Providers 2Health News:Enterprise Architecture -- Breaking Away From The Pack 2Health News:Surveillance colonoscopy should be targeted to high-risk patients 2Health News:NHLBI funds research to improve safety of red blood cell transfusions 2Health News:NHLBI funds research to improve safety of red blood cell transfusions 3Health News:NHLBI funds research to improve safety of red blood cell transfusions 4Health News:NHLBI funds research to improve safety of red blood cell transfusions 5Health News:NHLBI funds research to improve safety of red blood cell transfusions 6Health News:NHLBI funds research to improve safety of red blood cell transfusions 7
(Date:7/31/2014)... July 31, 2014  According to data released today ... 2015 average monthly Medicare Part D premium is expected ... than was originally projected, the Pharmaceutical Care Management Association ... continues to be a bright spot in American health ... each region and using cutting edge, cost-saving tools like ...
(Date:7/31/2014)... SAN DIEGO , July 31, 2014  Sorrento Therapeutics, ... death of Mr. Amar Singh , Chief Business Officer ... of apparent natural causes on July 30. "Sorrento ... dear friend and colleague. Our immediate thoughts go to Amar,s ... President and Chief Executive Officer. Mr. Singh ...
(Date:7/31/2014)... -- STAAR Surgical Company (NASDAQ: STAA ) ... and delivery systems for the eye today reported revenue ... $20.0 million, a 10% increase over $18.2 million reported ... currency basis, revenues grew 11% during the second quarter ... The effect of foreign currency exchange reduced sales by ...
Breaking Medicine Technology:Sorrento Announces the Unexpected Death of its Chief Business Officer 2STAAR Surgical Reports 10% Second Quarter Revenue Growth 2STAAR Surgical Reports 10% Second Quarter Revenue Growth 3STAAR Surgical Reports 10% Second Quarter Revenue Growth 4STAAR Surgical Reports 10% Second Quarter Revenue Growth 5STAAR Surgical Reports 10% Second Quarter Revenue Growth 6STAAR Surgical Reports 10% Second Quarter Revenue Growth 7STAAR Surgical Reports 10% Second Quarter Revenue Growth 8STAAR Surgical Reports 10% Second Quarter Revenue Growth 9STAAR Surgical Reports 10% Second Quarter Revenue Growth 10STAAR Surgical Reports 10% Second Quarter Revenue Growth 11STAAR Surgical Reports 10% Second Quarter Revenue Growth 12STAAR Surgical Reports 10% Second Quarter Revenue Growth 13STAAR Surgical Reports 10% Second Quarter Revenue Growth 14STAAR Surgical Reports 10% Second Quarter Revenue Growth 15STAAR Surgical Reports 10% Second Quarter Revenue Growth 16STAAR Surgical Reports 10% Second Quarter Revenue Growth 17STAAR Surgical Reports 10% Second Quarter Revenue Growth 18STAAR Surgical Reports 10% Second Quarter Revenue Growth 19STAAR Surgical Reports 10% Second Quarter Revenue Growth 20STAAR Surgical Reports 10% Second Quarter Revenue Growth 21STAAR Surgical Reports 10% Second Quarter Revenue Growth 22STAAR Surgical Reports 10% Second Quarter Revenue Growth 23STAAR Surgical Reports 10% Second Quarter Revenue Growth 24STAAR Surgical Reports 10% Second Quarter Revenue Growth 25STAAR Surgical Reports 10% Second Quarter Revenue Growth 26STAAR Surgical Reports 10% Second Quarter Revenue Growth 27STAAR Surgical Reports 10% Second Quarter Revenue Growth 28STAAR Surgical Reports 10% Second Quarter Revenue Growth 29STAAR Surgical Reports 10% Second Quarter Revenue Growth 30STAAR Surgical Reports 10% Second Quarter Revenue Growth 31
... 7 ActivBiotics, Inc. today,announced the results ... effect of rifalazil in the treatment of ... The results demonstrated,that treatment for two months ... in a significant improvement in walking distance,claudication ...
... the American Heart Association Scientific Sessions ... 2007 ... Nabi,Biopharmaceuticals (Nasdaq: NABI ) today announced the successful completion,of ... innovative and proprietary investigational vaccine being,developed to treat nicotine addiction ...
Cached Medicine Technology:Rifalazil Trial (PROVIDENCE-1) Fails to Provide Significant Clinical Benefit in Patients With Peripheral Arterial Disease 2Rifalazil Trial (PROVIDENCE-1) Fails to Provide Significant Clinical Benefit in Patients With Peripheral Arterial Disease 3Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 2Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 3Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 4Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 5Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 6Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months 7
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: