Navigation Links
Now hear this: Stanford researchers identify forerunners of inner-ear cells that enable hearing
Date:2/26/2013

colleagues identified a class of cells called tympanic border cells that can give rise to hair cells and the cells that support them during a phase of cochlear maturation right after birth.

"Until now, these cells have had no clear function," said Cheng. "We used several techniques to define their behavior in cell culture dishes, as well as in mice. I hope these findings will lead to new areas of research to better understand how our ears develop and perhaps new ways to stimulate the regeneration of sensory cells in the cochlea."

Cheng recently received a grant from the California Institute for Regenerative Medicine to study the limited regeneration of the same sensory hair cells that occur in a different region of the inner ear called the vestibular system, which helps us balance. Lessons learned there may also translate into aid for patients with hearing loss.

Although regeneration of sensory hair cells does not happen naturally, recent research has suggested that the mammalian ear may harbor a sub-population of presumably inactive progenitor cells. The research team led by Cheng and Nusse used a strain of laboratory mice that allowed the scientists to track the activation of a cell-signaling pathway driven by a protein called Wnt. The Wnt pathway has previously been shown to be involved in many developmental functions, and it drives the renewal and proliferation of many types of stem cells.

"We wanted to investigate the Wnt pathway because of its tremendous influence in the development and regeneration of many other organs," said Cheng.

The researchers found that tympanic border cells, or TBCs, which form a thin layer under the sensory epithelium, are actively dividing in mice during the first three weeks after birth (the time corresponding to about the first trimester of human development, during which the ability to hear is established) and give rise to at least a subset of sensory and non-sensory cells in the ear.
'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hear This: 3-D Printing Creates Lifelike Artificial Ears
2. Immune cells engineered in lab to resist HIV infection, Stanford study shows
3. Optogenetics illuminates pathways of motivation through brain, Stanford study shows
4. Stanford/Yale study gives insight into subtle genomic differences among our own cells
5. Mechanism found for destruction of key allergy-inducing complexes, Stanford researchers say
6. Stanford bioengineer Karl Deisseroth wins NIH Transformative Research Award
7. MBL and Stanford scientists receive 2012 Lasker Award for Basic Medical Research
8. Little evidence of health benefits from organic foods, Stanford study finds
9. Mathematics or memory? Stanford study charts collision course in brain
10. Stanford/Intel study details power of new chip to diagnose disease, analyze protein interactions
11. Community health centers compare well with private practices, Stanford researcher finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... South Coast Surety is pleased to welcome Richard Ford ... been known to the management of South Coast Surety ... of Georgia, majoring in Banking and Finance. He enjoyed a ... management of business equipment for a wide spectrum of industries ... a senior officer with a National firm that does design ...
(Date:3/30/2015)... Segundo, CA (PRWEB) March 30, 2015 Corra ... tests to accommodate the needs of every industry that requires ... employers face compliance mandates or seek new ways to increase ... adding new drug panels that will help detect substance abuse ... industries have mandated drug tests,” said Corra Group Co-Founder, Gordon ...
(Date:3/30/2015)... 2015 Mid-America ATTC has just ... medications used in behavioral health and addiction treatment. ... Android—is a convenient, electronic version of the helpful ... useful resource provides up-to-date information on generic and ... side effects, emergency conditions, cautions, considerations for pregnant ...
(Date:3/30/2015)... March 30, 2015 TherapySites, ... for mental health professionals, announced today its affiliation ... TherapySites to extend their online marketing solutions to ... , "As we continue to see advancements in ... the Internet effectively in order to succeed,” said ...
(Date:3/30/2015)... National Nutrition Month is an ... habits and commit to nutritious decisions that will affect their ... a recent study from the U.S. Department of Agriculture (USDA), ... Making healthy snack choices needs to be an essential piece ... on the go. , Each day, millions of Americans turn ...
Breaking Medicine News(10 mins):Health News:Richard Ford Joins South Coast Surety Contract Surety Team 2Health News:Corra Group Adds New Employment Screening Drug Test Solutions for Clients in Every Industry 2Health News:Corra Group Adds New Employment Screening Drug Test Solutions for Clients in Every Industry 3Health News:Popular Publication on Behavioral Health Medications Now An App 2Health News:TherapySites (Websites for Therapists) Partners with BehaveNet 2Health News:Benefits of Healthy Snacking — HealthyYOU Vending Machines Offer 21 Healthy Snack Selections for People on the Go 2Health News:Benefits of Healthy Snacking — HealthyYOU Vending Machines Offer 21 Healthy Snack Selections for People on the Go 3
... study was conducted to find out effective treatment for patients having ... ,The treatment tested was providing one full Lidoderm patch in the ... of the affected knee. The study result showed that after six ... the treatment reported about 30% pain relief or more. To the ...
... published in the Journal of American Medical Association, researchers said ... quality of life. ,The study conducted by Murdoch Children’s ... between obese children with non-obese children of the same age. ... more likely to become overweight as adults and may be ...
... Murdoch Childrens Research Institute and University of Melbourne, Australia ... ,The enzyme called ADAMTS5 destroys the cartilage by ... leads to inflammations and the severe joint pains that ... ,Arthritis is a condition that not only affects the ...
... standing may lead to more cases of mental illnesses ... a database of 34000 patients who have been detected ... the current issue of American Journal of Orthopsychiatry. ... occupational status leads to the social and economical standing ...
... sensory hair cells in the inner ear may restore partial ... published in Nature Medicine. , ,Scientists are of ... gene called Atoh1 can be used to encourage new hairs ... gene is also called Math1. The new sensory hairs grow ...
... say people aren’t the only organisms traveling around the ... ,Previous studies conducted among air travelers, including those involving ... within two rows of a contagious individual during a ... risk of getting the disease. Another study that examined ...
Cached Medicine News:
(Date:3/27/2015)... TEMPLE, Texas , March 27, 2015 The ... relocate in April to a 5,000-square-foot building at 1802 South ... a geographic area designated by the City of ... Baylor Scott & White and the Central Texas Veterans Health ... office and laboratory space to early stage biotechnology and life ...
(Date:3/27/2015)... 2015 A new report from Kalorama Information says ... – Chile , Colombia ... for IVD firms.  The healthcare research firm said that while ... for the Latin American continent with a population of over ... operations. However, the country,s regional economic clout does not necessarily ...
(Date:3/27/2015)... -- Zimmer Holdings, Inc. (NYSE and SIX: ZMH) is launching ... Available in both small (6mm) and large ... System from Zimmer is a modular system that offers surgeons ... XtraFix System allows surgeons to eliminate steps, as well ... in saved time, costs and overall team effort. ...
Breaking Medicine Technology:Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 4Zimmer Debuts New Modular External Fixation System 2Zimmer Debuts New Modular External Fixation System 3
... ANNAPOLIS, Md. and FAYETTEVILLE, Ark., April 4, 2012 ... provider SOAPware, Inc. have forged a strategic ... care practices transition from paper-based records to ... (EHR/EMR) systems. Together, the companies will work ...
... Texas Instruments Incorporated (TI) (NASDAQ: TXN ) ... family with five new fully integrated AFEs for portable ... (EEG) AFEs are the first to offer 16- and ... cut power consumption by more than 94 percent compared ...
Cached Medicine Technology:Syndicus, Inc. Scientific Services, SOAPware Announce Strategic Alliance 2TI introduces industry's first single- and dual-channel, 16- and 24-bit ECG/EEG analog front ends 2TI introduces industry's first single- and dual-channel, 16- and 24-bit ECG/EEG analog front ends 3TI introduces industry's first single- and dual-channel, 16- and 24-bit ECG/EEG analog front ends 4TI introduces industry's first single- and dual-channel, 16- and 24-bit ECG/EEG analog front ends 5
Tying forceps with 6.5 mm tying platform. Round handle with flats provide flexibility of round handle with the stability of a flat handle. Curved shafts. Overall length 3.9 inches....
Straight shafts with 4 mm tying platform. Serrated handle with dull finish. Manufactured in titanium. Overall length 3.3 inches....
Straight shafts with 6 mm tying platform. Wide serrated handle with polished finish. Overall length 4.3 inches. Overall length 4.3 inches....
Angled shafts with 10 mm tying platform. True round knurled handle in the closed position with polished finish. Overall length 4.2 inches....
Medicine Products: