Navigation Links
Now hear this: Stanford researchers identify forerunners of inner-ear cells that enable hearing
Date:2/26/2013

colleagues identified a class of cells called tympanic border cells that can give rise to hair cells and the cells that support them during a phase of cochlear maturation right after birth.

"Until now, these cells have had no clear function," said Cheng. "We used several techniques to define their behavior in cell culture dishes, as well as in mice. I hope these findings will lead to new areas of research to better understand how our ears develop and perhaps new ways to stimulate the regeneration of sensory cells in the cochlea."

Cheng recently received a grant from the California Institute for Regenerative Medicine to study the limited regeneration of the same sensory hair cells that occur in a different region of the inner ear called the vestibular system, which helps us balance. Lessons learned there may also translate into aid for patients with hearing loss.

Although regeneration of sensory hair cells does not happen naturally, recent research has suggested that the mammalian ear may harbor a sub-population of presumably inactive progenitor cells. The research team led by Cheng and Nusse used a strain of laboratory mice that allowed the scientists to track the activation of a cell-signaling pathway driven by a protein called Wnt. The Wnt pathway has previously been shown to be involved in many developmental functions, and it drives the renewal and proliferation of many types of stem cells.

"We wanted to investigate the Wnt pathway because of its tremendous influence in the development and regeneration of many other organs," said Cheng.

The researchers found that tympanic border cells, or TBCs, which form a thin layer under the sensory epithelium, are actively dividing in mice during the first three weeks after birth (the time corresponding to about the first trimester of human development, during which the ability to hear is established) and give rise to at least a subset of sensory and non-sensory cells in the ear.
'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hear This: 3-D Printing Creates Lifelike Artificial Ears
2. Immune cells engineered in lab to resist HIV infection, Stanford study shows
3. Optogenetics illuminates pathways of motivation through brain, Stanford study shows
4. Stanford/Yale study gives insight into subtle genomic differences among our own cells
5. Mechanism found for destruction of key allergy-inducing complexes, Stanford researchers say
6. Stanford bioengineer Karl Deisseroth wins NIH Transformative Research Award
7. MBL and Stanford scientists receive 2012 Lasker Award for Basic Medical Research
8. Little evidence of health benefits from organic foods, Stanford study finds
9. Mathematics or memory? Stanford study charts collision course in brain
10. Stanford/Intel study details power of new chip to diagnose disease, analyze protein interactions
11. Community health centers compare well with private practices, Stanford researcher finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... 23, 2014 "I have heard female ... a urine sample," said an inventor from Lake Stevens, ... and mess-free, I came up with this urine-collection aid." ... samples to be collected from women more easily. The ... to patients and staff. The invention improves sanitation and ...
(Date:8/23/2014)... Peripheral intervention surgeries are part of ... thereby addressing the root cause of peripheral artery disease. ... the other part of the arteries where the blood ... require the use of a catheter, (which is a ... catheters are inserted through a thin cut in an ...
(Date:8/23/2014)... A team of New York researchers say ... preceded by surgery and delivered by an experienced team. Surviving ... Click here to read it now . , ... of mesothelioma patients who underwent hemithoracic (one side of ... the shape of a tumor. Patients who had surgery ...
(Date:8/23/2014)... GBI Research, the leading business intelligence provider, has ... Developed Markets to 2020 - New and Late-Stage Four-Factor ... in-depth analysis of the critical care market in the ... The report provides an estimation of market size for ... critical care indications that are being treated using the ...
(Date:8/23/2014)... Young adults in Athens, GA who find that they have a ... and call the new helpline which can offer support and guidance ... Teen Athens is a wonderful resource for an adolescent drug or ... to end substance abuse once and for all. When a young ... peers when really they should put their faith in a youth ...
Breaking Medicine News(10 mins):Health News:Global Peripheral Intervention Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Health News:Global Peripheral Intervention Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Health News:Global Peripheral Intervention Market: Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 4Health News:New Study Links Hospital Experience and Prior Surgery with Mesothelioma Radiation Success, According to Surviving Mesothelioma 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 3Health News:Teenagers in Athens, GA are Locating Addiction Recovery Thanks to New Helpline 2
... own bone marrow stem cells after a heart attack ... Emory University School of Medicine physicians has found. , ... Emory University School of Medicine, presents the results Monday ... , "These results show that treatment with a patient,s ...
... highest channel-count 12-bit ADC reduces I/O pin ... SANTA CLARA, Calif., March 30 /PRNewswire/ ... mixed-signal compression solutions for intelligent data conversion, ... of analog-to-digital converters (ADCs) integrated with the ...
... Genaera Corporation (Nasdaq: GENR ) today announced ... cash resources in order to maintain the ability to ... highly selective inhibitor of PTP1B and Genaera,s lead drug ... obesity, and explore strategic alternatives. The Company will ...
... 21 is pleased to announce that Michael A. ... elected to the board of directors of the ... a 128-year old trade association representing manufacturers and ... Members were elected at the association,s March ...
... Billion Each Year According to the Better Sleep CouncilDALLAS, March ... Unfortunately, sleep is usually one of the first things people ... In a turbulent economy, nearly 30 percent of Americans ... according to a 2009 Sleep in America poll by the ...
... A health insurance protocol intended to ... barriers that lead people to receive less of needed ... result, patients ultimately require more -- and more costly ... plan members to try a first-line medication before they ...
Cached Medicine News:Health News:After heart attack, bone marrow stem cells increase blood flow within heart 2Health News:Samplify Rolls Production Quantities of Its SAM1600 Analog/Digital Converters with Real-Time Data Compression 2Health News:Samplify Rolls Production Quantities of Its SAM1600 Analog/Digital Converters with Real-Time Data Compression 3Health News:Genaera Corporation Implements Cash Conservation Plan 2Health News:Nutrition 21's President and CEO, Elected to the Consumer Healthcare Products Association Board 2Health News:Nutrition 21's President and CEO, Elected to the Consumer Healthcare Products Association Board 3Health News:It Pays to Sleep: Prioritize Rest to Boost Health, Morale and Revenue 2Health News:It Pays to Sleep: Prioritize Rest to Boost Health, Morale and Revenue 3Health News:Thomson Reuters Study Finds Step Therapy Programs May Increase Overall Healthcare Costs for Employers 2Health News:Thomson Reuters Study Finds Step Therapy Programs May Increase Overall Healthcare Costs for Employers 3
(Date:8/22/2014)... 2014   Zacks Equity Research highlights Epizyme (Nasdaq: ... and Panera (Nasdaq: PNRA - Free Report ) as the ... on Amicus Therapeutics (Nasdaq: FOLD - Free Report ), Sanofi ... SHPG - Free Report ). Here is a synopsis ... Day : The biotech bull market is far ...
(Date:8/22/2014)... , Aug. 22, 2014  Cannabis Science, Inc. ... formulation-based drug development and related consulting, is pleased ... international medical cannabis conference taking place at the ... , on October 22, 2014.  The multilingual ... such as researchers, health professionals, and patients, to ...
(Date:8/21/2014)... Memorial Hermann Health System and The University of ... partnership to provide a new level of specialized breast screening ... greater Houston area. Starting ... of professional breast radiology services for five of Memorial Hermann,s ... The Woodlands , Northeast, Southwest and Sugar ...
Breaking Medicine Technology:Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 3Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 4Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 5Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 6Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 2Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 2Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 3Memorial Hermann, MD Anderson join forces to provide enhanced breast imaging services throughout the Greater Houston Region 4
... NEW YORK, Dec. 14, 2010 Reportlinker.com ... is available in its catalogue: ... Electrophysiology & Ablation Devices 2011 ... In 2010, the Asia Pacific markets for ...
... YORK, Dec. 14, 2010 Reportlinker.com announces that a ... The Clinical Trials Business ... and the outsourcing of clinical trials to lower-cost countries ... the U.S. to a 3.3% compound annual growth rate ...
Cached Medicine Technology:Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 2Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 3Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 4Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 5Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 6Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 7Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 8Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 9Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 10Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 11Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 12Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 13Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 14Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 15Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 16Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 17Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 18Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 19Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 20Reportlinker Adds Asia-Pacific Markets for Cardiac Rhythm Management, Electrophysiology & Ablation Devices 2011 21Reportlinker Adds The Clinical Trials Business 2Reportlinker Adds The Clinical Trials Business 3Reportlinker Adds The Clinical Trials Business 4Reportlinker Adds The Clinical Trials Business 5Reportlinker Adds The Clinical Trials Business 6Reportlinker Adds The Clinical Trials Business 7Reportlinker Adds The Clinical Trials Business 8Reportlinker Adds The Clinical Trials Business 9Reportlinker Adds The Clinical Trials Business 10Reportlinker Adds The Clinical Trials Business 11Reportlinker Adds The Clinical Trials Business 12Reportlinker Adds The Clinical Trials Business 13
... from end, Cannula comes with 20cm (8 in) ... Capable of withstanding injections of viscoelastic fluids. ID-0.50mm ... lock, high pressure extension tubing set., 20cm (8 ... (Cannulas come with 20cm luer lock, high ...
Multi-sided, Sharp all around...
2.5mm...
...
Medicine Products: