Navigation Links
Now hear this: Stanford researchers identify forerunners of inner-ear cells that enable hearing
Date:2/26/2013

colleagues identified a class of cells called tympanic border cells that can give rise to hair cells and the cells that support them during a phase of cochlear maturation right after birth.

"Until now, these cells have had no clear function," said Cheng. "We used several techniques to define their behavior in cell culture dishes, as well as in mice. I hope these findings will lead to new areas of research to better understand how our ears develop and perhaps new ways to stimulate the regeneration of sensory cells in the cochlea."

Cheng recently received a grant from the California Institute for Regenerative Medicine to study the limited regeneration of the same sensory hair cells that occur in a different region of the inner ear called the vestibular system, which helps us balance. Lessons learned there may also translate into aid for patients with hearing loss.

Although regeneration of sensory hair cells does not happen naturally, recent research has suggested that the mammalian ear may harbor a sub-population of presumably inactive progenitor cells. The research team led by Cheng and Nusse used a strain of laboratory mice that allowed the scientists to track the activation of a cell-signaling pathway driven by a protein called Wnt. The Wnt pathway has previously been shown to be involved in many developmental functions, and it drives the renewal and proliferation of many types of stem cells.

"We wanted to investigate the Wnt pathway because of its tremendous influence in the development and regeneration of many other organs," said Cheng.

The researchers found that tympanic border cells, or TBCs, which form a thin layer under the sensory epithelium, are actively dividing in mice during the first three weeks after birth (the time corresponding to about the first trimester of human development, during which the ability to hear is established) and give rise to at least a subset of sensory and non-sensory cells in the ear.
'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hear This: 3-D Printing Creates Lifelike Artificial Ears
2. Immune cells engineered in lab to resist HIV infection, Stanford study shows
3. Optogenetics illuminates pathways of motivation through brain, Stanford study shows
4. Stanford/Yale study gives insight into subtle genomic differences among our own cells
5. Mechanism found for destruction of key allergy-inducing complexes, Stanford researchers say
6. Stanford bioengineer Karl Deisseroth wins NIH Transformative Research Award
7. MBL and Stanford scientists receive 2012 Lasker Award for Basic Medical Research
8. Little evidence of health benefits from organic foods, Stanford study finds
9. Mathematics or memory? Stanford study charts collision course in brain
10. Stanford/Intel study details power of new chip to diagnose disease, analyze protein interactions
11. Community health centers compare well with private practices, Stanford researcher finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... October 22, 2014 For Dr. Iris Hunter, ... money; it’s an extension of her life’s mission. Her extensive ... as the owner of FirstLight HomeCare, make it clear that ... to me that my work makes a difference in the ... entrepreneurial spirit, so after much research, I felt ready to ...
(Date:10/22/2014)... California (PRWEB) October 22, 2014 Hay House ... Move Beyond Addiction and Upgrade Your Life (Paperback; $10.82) written ... of Yoga & Recovery. This book is meant to ... in a life of recovery. , Recovery 2.0 is ... 12 Steps; Recovery 2.0 is a guide for what comes ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Losing Weight Your ... industry is staring you in the face, it certainly can ... not do your body an extra favor by doing it ... tempting crash diets. Instead, listen to your body, exercise regularly, ... Exercise is essential to losing weight; you need to exercise ...
(Date:10/22/2014)... Steven Reinberg HealthDay Reporter ... quickly add weight and length may be showing a genetic ... In adults, certain genes have been linked to increased body ... in fat and lean muscle, the researchers said. At ... taller. By ages 2 and 3, however, these genes were ...
(Date:10/22/2014)... (HealthDay News) -- Measures taken by Firestone officials at ... may have limited the spread of the disease there ... Firestone Natural Rubber Co. provides health services to about ... densely populated communities. Between Aug. 1 and Sept. ... among those 80,000 people. That incidence rate of 0.09 ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:ReductionGuruMD Presents Ways to Improve Your Weight Loss Results 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2
... impair the cognitive health of people, but now scientists ... memory problems. A new National Institutes of Health ... of a stress hormone produced by the adrenal gland ... of the brain responsible for learning and short-term memory. ...
... professor of psychiatry and human behavior at The Warren Alpert ... Control & Diabetes Research Center at The Miriam Hospital, people ... who lose weight and keep the pounds off, have made ... Using new research findings, Wing will make her case for ...
... Drug-Resistant Killers of the 21st Century , WHO: , ... Thomas Lietman, University of California, San Francisco , ... State University , Peter Small, Bill and Melinda ... Ramanan Laxminarayan, Resources for the Future , ...
... is crucial to understanding psychosis, but there is more ... Arizona State University bioethicist and philosopher of science. , ... complexity of classification and diagnosis, Robert explains. But I ... psychiatrist often ill, unhappy people who behave in ...
... National Osteoporosis Foundation, osteoporosis affects some 25 million Americans ... causes a thinning of the bone, it can lead ... of debilitating and sometimes deadly complications. , Bisphosphonates (BFs), ... class of drugs that act to prevent bone fractures ...
... ... WASHINGTON, Feb. 16 As President Bush begins,a five-country tour ... Emergency Plan for AIDS Relief (PEPFAR), the five year-old US,global ... (AHF) ( http://www.aidshealth.org ) today cautioned the President,that his legacy ...
Cached Medicine News:Health News:Stress hormone impacts memory, learning in diabetic rodents 2Health News:Large changes needed to address global obesity epidemic 2Health News:Arizona State bioethicist says mental illness is subject to biological and sociocultural factors 2Health News:Arizona State bioethicist says mental illness is subject to biological and sociocultural factors 3Health News:Link between treating osteoporosis with bisphosphonates and incidence of bone necrosis examined 2Health News:Bush AIDS Legacy at Risk, Says AHF 2
(Date:10/20/2014)... 20 de octubre de 2014  PneumRx, Inc. ... de la pulmonología intervencional, anunció hoy la conclusión ... 3 meses antes de lo programado. El Estudio Clínico ... dispositivo de investigación (IDE) aprobada por la FDA ... de espiral de reducción de volumen pulmonar PneumRx ...
(Date:10/20/2014)... Oct. 20, 2014  ResMed (NYSE: ... ResMed Data Exchange program, a comprehensive suite of ... (HME) and other health care providers. ... to critical patient information. It integrates valuable sleep ... U-Sleep™ patient management platforms with customers, in-house or ...
(Date:10/20/2014)... 2014  AnaptysBio, Inc., a leader in the ... the appointment of Marco Londei , M.D. ... the preclinical and clinical development of AnaptysBio,s proprietary ... to welcome Dr. Londei to AnaptysBio,s executive leadership ... Chief Executive Officer of AnaptysBio. "Dr. Londei,s extensive ...
Breaking Medicine Technology:PneumRx concluye inscripción en prueba fundamental RENEW 2PneumRx concluye inscripción en prueba fundamental RENEW 3ResMed Launches ResMed Data Exchange 2AnaptysBio Appoints Dr. Marco Londei to Newly Created Chief Development Officer Position Clinical Immunologist to Lead AnaptysBio's Pipeline Advancement 2
... 9, 2012  Medical Director for WAISMANN METHOD® rapid ... Michael Lowenstein, announced his support for National Fibromyalgia Awareness ... number of fibromyalgia patients are being prescribed opiate painkillers ... to Dr. Lowenstein as prescription painkiller use is also ...
... 8, 2012  Coloplast North America today announced that a ... Medical Devices, Inc. (GMD) was infringing on a Coloplast ... treating stress urinary incontinence in women. Using this approach, ... women regain control of their bladder. The ...
Cached Medicine Technology:WAISMANN METHOD® Medical Director Voices Support for Fibromyalgia Awareness Day 2Coloplast Wins Patent Infringement Verdict Against Generic Medical Devices, Inc. 2
... Mouthpiece 7FT O 2 Tubing Tee Adapter, ... for fast treatment times , ... (higher percentage of respirable particles) than conventional nebulizers, ... Max 10™ disposable nebulizers deliver fast and effective ...
Nebulizer Custom Kit...
... Anesthesia and Respiratory Products, ,Westmed designs, ... for Anesthesia and Respiratory professionals. Our mission ... enhance the clinician's ability to deliver quality ... the bottom line. , ,Our web ...
... Products, ,Westmed designs, manufacturers and markets ... Respiratory professionals. Our mission is to design ... ability to deliver quality medical care while ... , ,Our web site is designed ...
Medicine Products: