Navigation Links
Nobelist James Watson proposes an unconventional view of type 2 diabetes causation
Date:2/27/2014

Cold Spring Harbor, NY At 85, Nobel laureate James D. Watson, the co-discoverer of the double-helix structure of DNA, continues to advance intriguing scientific ideas. His latest, a hypothesis on the causation of type 2 diabetes, is to appear 7 pm Thursday US time in the online pages of The Lancet, the prestigious British medical journal.

Watson's hypothesis, which is featured as the Lancet cover story in the U.S. print edition dated March 1-7, 2014, suggests that diabetes, dementias, cardiovascular disease, and some cancers are linked to a failure to generate sufficient biological oxidants, called reactive oxygen species (ROS). Watson also argues the case for a better understanding of the role of exercise in helping to remedy this deficiency.

"The prevalent view of type 2 diabetes," Dr. Watson says, "is that an excess of intracellular oxidation causes inflammation, which in turn kills cells in pancreatic tissue." Proper function of those cells, it is well understood, is critical for the maintenance of normal blood glucose levels.

Over the last several years Watson has been puzzling out an alternative view, based on facts reported in the peer-reviewed literature of medicine and molecular biology. (He makes clear that he is not a medical doctor, rather a student of science.) He does not question that pancreatic tissue in people with type 2 diabetes is indeed inflamed. But he does present a novel theory of why. "The fundamental cause, I suggest, is a lack of biological oxidants, not an excess," he says.

For years, Watson knew, doctors have been telling patients with incipient type 2 diabetes those with high blood sugar levels -- to exercise, often before putting them on a well-proven glucose-lowering drug regimen such as Metformin. Exercise seemed to Watson the key to the puzzle: what was it about exercise that served to benefit people with high blood sugar?

There were important clues, he specul
'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Medical Tourism: Uncharted Territory for Patients James Goldberg, Author of the American Medical Money Machine, Is Offering a New Consulting Service to Medical Patients Considering “Medical Tourism” Treatment
2. James George, MD: 2012 ASH Wallace H. Coulter Award for Lifetime Achievement in Hematology
3. Before Skyfall: 46 years of violence in James Bond movies
4. NAI Fellows Robert Langer, Leroy Hood and Member James Wynne receive US National Medals
5. Nobel laureate James Watson publishes novel hypothesis on curing late-stage cancers
6. Driving While Drowsy in Buffalo: Lawyer James E. Morris Urges Motorists To Wake Up to the Facts
7. Dr. James Wanless on Tarot, Kathi Kennedi on Hypno-Reiki, Nina Rehzats & Teresa Figueroa on Quantum Healing, Suzy Prudden on Making Money on Dr. Carol Francis Radio Show
8. Eldon James Highlights Eco-Friendly Tubing and Fitting Assemblies at MedTec Europe
9. A-lign Senior Consultant James McAllister Receives QSA Certification
10. Complete Currency Trader: Review Of James Edward's Advanced Forex Trading Course Released
11. Brain researcher James Poulet receives the 2013 Paul Ehrlich Prize for Young Researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... ... July 03, 2015 , ... ... healthcare providers, has been retained to lead a national chief nursing officer ... top-ranked executive search firms in the healthcare industry, B. E. Smith has recently ...
(Date:7/3/2015)... ... , ... First Choice Emergency Room , the largest network of independent ... new Medical Director of its Frisco facility. , “We are pleased to announce that ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:7/2/2015)... ... 02, 2015 , ... sweetFrog Enterprises, LLC. is pleased to announce the opening ... store located in Mississippi. The premium frozen yogurt chain was listed as #22 on ... at 104 Railroad Avenue, New Albany, MS 38652, will have a grand opening event ...
(Date:7/2/2015)... WIsconsin (PRWEB) , ... July 02, 2015 , ... ... for the parking structure retrofit project at the University of Minnesota, they knew ... is that it would also be an award-winning choice: the total energy savings ...
(Date:7/2/2015)... ... July 02, 2015 , ... As Americans celebrate the Fourth of July outdoors ... is on the rise. July is UV Safety Month, and physicians at American Family ... of getting skin checks. Experts say most skin cancers can be found early with ...
Breaking Medicine News(10 mins):Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Jane Phillips Medical Center Retains B. E. Smith to Recruit New Chief Nursing Officer 3Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3Health News:sweetfrog Opens First Location in Mississippi 2Health News:Kenall’s TekDek™ Helps University Achieve Award-Winning Energy Savings in Parking Structure Lighting Retrofit 2Health News:Local Physicians Warn of Holiday Health Hazards 2Health News:Local Physicians Warn of Holiday Health Hazards 3Health News:Local Physicians Warn of Holiday Health Hazards 4
... Four other factors, including gender and weight, play role ... 16 (HealthDay News) -- When it comes to the ... traditionally focused on is gestational age, but a new ... several factors that physicians and parents should consider when ...
... 17 A few years back, the,standard business card had ... side of plain vanilla paper stock, sometimes with,two-color printing to ... on both,sides of a BC in four-color process with a ... for 500 cards. This is a fraction,of what it cost ...
... CRM Holdings,Ltd. ("the Company") (Nasdaq: CRMH ) ... wholly-owned subsidiary of the Company, has,received notice from ... following an initial investigation, the WCB has determined ... CRM,s third party,administrator,s license to provide third party ...
... 16 Spencer Wyatt, an 8-year-old boy,living with epilepsy, ... Canine Assistants and UCB, Inc., the exclusive sponsor of ... in frequency and severity-allowing him to play sports, take,music ... that he may have,a seizure when his parents are ...
... Champions on Capitol Hill to Ask U.S. to,Meet Obligations ... The White Ribbon,Alliance for Safe Motherhood today took its ... Capitol Hill. Citing recent reports that the UN,Millennium Development ... is,unlikely to be met in Asia until 2076 and ...
... Restaurants Required to Provide Calorie Information, ALEXANDRIA, ... applauds today,s federal court ruling upholding,a New York ... the,calorie content of foods on their menus and ... challenge to the regulation filed by the New ...
Cached Medicine News:Health News:Gestational Age Not Sole Predictor of Preemie Survival 2Health News:Gestational Age Not Sole Predictor of Preemie Survival 3Health News:Your Business Card is a Powerful Marketing Tool 2Health News:Compensation Risk Managers, LLC Receives Notice of Administrative Action by New York Workers' Compensation Board 2Health News:Compensation Risk Managers, LLC Receives Notice of Administrative Action by New York Workers' Compensation Board 3Health News:Young Boy With Epilepsy to Gain Independence With New Seizure Response Dog From Canine Assistants 2Health News:White Ribbon Alliance Calls for Investments to Save Women's Lives Lost in Pregnancy and Childbirth 2Health News:Statement of the American Diabetes Association Supporting Federal Court's Ruling on New York City Proposal 2
(Date:7/3/2015)... 3, 2015 Un fournisseur ... que sont l,hypertension, le diabète et les troubles ... éducatives gratuites et d,une conférence majeure dédiée à ... ) , Les formations ... Prendre en charge l,hypertension en ligne ...
(Date:7/2/2015)... 3, 2015 Pharma Major ... de participación en ZAO "Biocom" en Rusia bajo ... incursión de Lupin en el mercado farmacéutico de ... ventas, colocándolo como uno de los 10 principales ... Durante más de una década, el mercado farmacéutico ...
(Date:7/2/2015)... N.C. , July 2, 2015  New product ... of its leading role in educating thought leaders about ... that can heavily influence how well a new therapy ... new study from research and consulting leader Best Practices, ... leaders need to focus on are early stage thought ...
Breaking Medicine Technology:Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 2Lutter contre trois maladies chroniques majeures en Amérique latine grâce à la formation médicale 3Lupin adquiere Biocom en Rusia 2Lupin adquiere Biocom en Rusia 3Medical Affairs Role in Thought Leader Education is Key Success Factor for New Product Launches in the Pharmaceutical Industry 2
... post-surgery hormone therapy reduced risk of breast cancer return ... First Phase III data to substantiate anticancer effect of ... prevention of bone complications due to bone metastases, with ... Feb. 11 /PRNewswire/ -- A newly published ...
... test to help guide treatment decisionsANN ARBOR, Mich., Feb. ... Comprehensive Cancer Center have identified a panel of ... prostate cancer.The finding could lead to a simple test ... slow-growing and which require immediate, aggressive treatment.Results of the ...
Cached Medicine Technology:Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 2Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 3Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 4Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 5Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 6Video: Zometa(R) Reduces Risk of Breast Cancer Recurrence in Premenopausal Women, Study in The New England Journal of Medicine Reports 7Researchers Discover Metabolite Linked to Aggressive Prostate Cancer 2Researchers Discover Metabolite Linked to Aggressive Prostate Cancer 3
TD silicone foam compression pad. Use with plates sealed with TDX or OptiTape....
The MicroAmp Centrifuge Adapter accomodates a single MicroAmp Reaction Tube with Cap and fits a standard microcentrifuge rotor. The adapter can be used up to 15,000 x g and should be used in pairs to...
PCR Workstation brings together UV irradiation and antimicrobial stainless steel to create a dual-attack environment against PCR contamination. PCR Workstation now available with a UV/Air Circulator ...
... tube racks. Its camera-based vision system captures and ... rack, making it ideal for use in automated ... a rack to be read automatically and can ... safety switch prevents a rack from being read ...
Medicine Products: