Navigation Links
Nobelist James Watson proposes an unconventional view of type 2 diabetes causation
Date:2/27/2014

Cold Spring Harbor, NY At 85, Nobel laureate James D. Watson, the co-discoverer of the double-helix structure of DNA, continues to advance intriguing scientific ideas. His latest, a hypothesis on the causation of type 2 diabetes, is to appear 7 pm Thursday US time in the online pages of The Lancet, the prestigious British medical journal.

Watson's hypothesis, which is featured as the Lancet cover story in the U.S. print edition dated March 1-7, 2014, suggests that diabetes, dementias, cardiovascular disease, and some cancers are linked to a failure to generate sufficient biological oxidants, called reactive oxygen species (ROS). Watson also argues the case for a better understanding of the role of exercise in helping to remedy this deficiency.

"The prevalent view of type 2 diabetes," Dr. Watson says, "is that an excess of intracellular oxidation causes inflammation, which in turn kills cells in pancreatic tissue." Proper function of those cells, it is well understood, is critical for the maintenance of normal blood glucose levels.

Over the last several years Watson has been puzzling out an alternative view, based on facts reported in the peer-reviewed literature of medicine and molecular biology. (He makes clear that he is not a medical doctor, rather a student of science.) He does not question that pancreatic tissue in people with type 2 diabetes is indeed inflamed. But he does present a novel theory of why. "The fundamental cause, I suggest, is a lack of biological oxidants, not an excess," he says.

For years, Watson knew, doctors have been telling patients with incipient type 2 diabetes those with high blood sugar levels -- to exercise, often before putting them on a well-proven glucose-lowering drug regimen such as Metformin. Exercise seemed to Watson the key to the puzzle: what was it about exercise that served to benefit people with high blood sugar?

There were important clues, he specul
'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Medical Tourism: Uncharted Territory for Patients James Goldberg, Author of the American Medical Money Machine, Is Offering a New Consulting Service to Medical Patients Considering “Medical Tourism” Treatment
2. James George, MD: 2012 ASH Wallace H. Coulter Award for Lifetime Achievement in Hematology
3. Before Skyfall: 46 years of violence in James Bond movies
4. NAI Fellows Robert Langer, Leroy Hood and Member James Wynne receive US National Medals
5. Nobel laureate James Watson publishes novel hypothesis on curing late-stage cancers
6. Driving While Drowsy in Buffalo: Lawyer James E. Morris Urges Motorists To Wake Up to the Facts
7. Dr. James Wanless on Tarot, Kathi Kennedi on Hypno-Reiki, Nina Rehzats & Teresa Figueroa on Quantum Healing, Suzy Prudden on Making Money on Dr. Carol Francis Radio Show
8. Eldon James Highlights Eco-Friendly Tubing and Fitting Assemblies at MedTec Europe
9. A-lign Senior Consultant James McAllister Receives QSA Certification
10. Complete Currency Trader: Review Of James Edward's Advanced Forex Trading Course Released
11. Brain researcher James Poulet receives the 2013 Paul Ehrlich Prize for Young Researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... (HealthDay News) -- Not getting the right amount of ... new study suggests. Those who sleep less or ... night may be more prone to developing the chronic ... The study authors concluded that duration and quality of ... with inflammatory bowel diseases. "Both short and long ...
(Date:10/25/2014)... A large influx of international aid is needed, and ... thousands of deaths from the widening Ebola crisis, a ... a specially designed mathematical model, the researchers looked at ... densely populated county of hard-hit Liberia -- Montserrado County, ... researchers said that if international aid isn,t delivered to ...
(Date:10/25/2014)... HealthDay Reporter FRIDAY, Oct. 24, 2014 (HealthDay ... increased risks for certain cancers, one might think that high-risk ... a new study suggests that, at least with colon cancer, ... genes doubled their risk of colon cancer were no more ... "It didn,t make any difference, not at all," said study ...
(Date:10/22/2014)... 22, 2014 At a time when ... parents and athletes at all levels, the UPMC ... the current discussion where two powerful messages are lost: ... that result in full recoveries every day. , In ... in fact and research, UPMC and the Concussion Program ...
(Date:10/22/2014)... Austin, TX (PRWEB) October 22, 2014 ... Criminal Minds featuring skin diseases both fictional ... Foundation (CEHMDF), a nonprofit organization committed to advocacy ... wondering if CBS will take the opportunity to impart ... disease. , There are many misconceptions about ...
Breaking Medicine News(10 mins):Health News:Sleep Duration Linked to Ulcerative Colitis Risk in Study 2Health News:Experts Predict 'Catastrophic' Ebola Epidemic in West Africa if Aid Delayed 2Health News:Knowing Genetic Risk for Cancer May Not Change Behavior 2Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 2Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 3Health News:University of Pittsburgh Medical Center Launches Initiative to Emphasize Concussions Are Treatable 4Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3
... SaaS Compliance Manager Enables PHNS and Healthcare Organizations ... ... Regulations, BATON ROUGE, La., Nov. 16 ... with PHNS, making its web-based Compliance Manager available to,hundreds of healthcare ...
... to Improved HIV Management in Developing World, UPPSALA, ... has signed an agreement with a consortium of American ... of operational,funding, and has committed to raising additional funding ... Cavidi,s newly adopted three-year,business plan. Cavidi is the producer ...
... Disclosures for Separate Account J, WASHINGTON, Nov. ... a Department of Labor investigation, launched in 2002,regarding ... of 1974 (ERISA). The Department of Labor ... pension plan, ultimately focused on whether the compensation,arrangements ...
... Sexual Behavior, Sexual Desire, ... WHAT: Are medicine and technology changing human sexuality? Does gender ... in the quality of life of people ... compelling issues on human sexuality will be the focus of ...
... HealthPartners,is the top-performing health plan in the nation ... released business report. The report, sponsored by the,National Business ... for,information tool. The tool is used by purchasers across ... Care Action Group, a coalition of,private and public employers., ...
... - December 31, TULSA, Okla., Nov. 16 ... it will offer three Medicare Part D,prescription drug plans ... Medicare. Medicare beneficiaries in Oklahoma can sign,up for or ... 2008,annual open enrollment period, which begins November 15 and ...
Cached Medicine News:Health News:TraceSecurity Announces Partnership with PHNS Expanding Compliance Services to Hundreds of Healthcare Systems 2Health News:TraceSecurity Announces Partnership with PHNS Expanding Compliance Services to Hundreds of Healthcare Systems 3Health News:New Investors Fund Expansion of Cavidi AB 2Health News:ULLICO Inc. and U.S. Department of Labor Agree to Resolve 5 Year Old ERISA Investigation 2Health News:ULLICO Inc. and U.S. Department of Labor Agree to Resolve 5 Year Old ERISA Investigation 3Health News:Charlie Rose Science Series 2Health News:HealthPartners is National Benchmark in Six Out of Seven Areas in National Business Coalition on Health Report 2Health News:Blue Cross and Blue Shield of Oklahoma Announces Flexible, Affordable Blue MedicareRx(SM) Medicare Prescription Drug Plans 2
(Date:10/22/2014)... -- Investor-Edge has initiated coverage on the ... ), Progenics Pharmaceuticals Inc. (NASDAQ: PGNX ), ... Pharmaceuticals Inc. (NASDAQ: IDRA ), and Merrimack ... companies can be accessed at: http://investor-edge.com/register . ... ended at 4,419.48, up 2.40%, the Dow Jones Industrial ...
(Date:10/22/2014)... RIDGE, N.J. , Oct. 22, 2014 /PRNewswire/ ... (RMANJ), a world-renowned leader in the field of ... rapid approach to embryonic screening. The research abstract, ... Society for Reproductive Medicine (ASRM) meeting in ... screening (CCS) and single gene defect (SGD) pre-implantation ...
(Date:10/22/2014)... Oct. 22, 2014 AVACEN Medical announced today ... 510 (k) OTC clearance by the U.S. Food and ... be marketed over the Internet for: the temporary ... and minor strains and sprains . Logo ... 100 (MSRP $2495) is a sophisticated medical device incorporating ...
Breaking Medicine Technology:Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 2Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 3Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 4Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 5New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2
... Marco's American standard, corrected curve trial lenses are ... used in Marco refractors and are invaluable in ... sets of other manufacturers contain a disproportionately large ... are less expensive to produce, and fewer lenses ...
... brings new freedom and portability to ... and excellence that are the hallmark ... eyecare practitioners a simple, affordable, and ... utilizes the same proven technology of ...
The Electric H-Base Table is for heavier instruments, or for those who prefer electric elevation. The electric table easily accepts a slit lamp, a single tabletop, or a double tabletop, just as the M...
... or for those seeking high quality ... is an economical, full-function instrument-delivery system. ... body offer rugged, maintenance-free service. And ... two arms provided as standard equipment--adjusts ...
Medicine Products: