Navigation Links
Nobelist James Watson proposes an unconventional view of type 2 diabetes causation
Date:2/27/2014

Cold Spring Harbor, NY At 85, Nobel laureate James D. Watson, the co-discoverer of the double-helix structure of DNA, continues to advance intriguing scientific ideas. His latest, a hypothesis on the causation of type 2 diabetes, is to appear 7 pm Thursday US time in the online pages of The Lancet, the prestigious British medical journal.

Watson's hypothesis, which is featured as the Lancet cover story in the U.S. print edition dated March 1-7, 2014, suggests that diabetes, dementias, cardiovascular disease, and some cancers are linked to a failure to generate sufficient biological oxidants, called reactive oxygen species (ROS). Watson also argues the case for a better understanding of the role of exercise in helping to remedy this deficiency.

"The prevalent view of type 2 diabetes," Dr. Watson says, "is that an excess of intracellular oxidation causes inflammation, which in turn kills cells in pancreatic tissue." Proper function of those cells, it is well understood, is critical for the maintenance of normal blood glucose levels.

Over the last several years Watson has been puzzling out an alternative view, based on facts reported in the peer-reviewed literature of medicine and molecular biology. (He makes clear that he is not a medical doctor, rather a student of science.) He does not question that pancreatic tissue in people with type 2 diabetes is indeed inflamed. But he does present a novel theory of why. "The fundamental cause, I suggest, is a lack of biological oxidants, not an excess," he says.

For years, Watson knew, doctors have been telling patients with incipient type 2 diabetes those with high blood sugar levels -- to exercise, often before putting them on a well-proven glucose-lowering drug regimen such as Metformin. Exercise seemed to Watson the key to the puzzle: what was it about exercise that served to benefit people with high blood sugar?

There were important clues, he specul
'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-5055
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Medical Tourism: Uncharted Territory for Patients James Goldberg, Author of the American Medical Money Machine, Is Offering a New Consulting Service to Medical Patients Considering “Medical Tourism” Treatment
2. James George, MD: 2012 ASH Wallace H. Coulter Award for Lifetime Achievement in Hematology
3. Before Skyfall: 46 years of violence in James Bond movies
4. NAI Fellows Robert Langer, Leroy Hood and Member James Wynne receive US National Medals
5. Nobel laureate James Watson publishes novel hypothesis on curing late-stage cancers
6. Driving While Drowsy in Buffalo: Lawyer James E. Morris Urges Motorists To Wake Up to the Facts
7. Dr. James Wanless on Tarot, Kathi Kennedi on Hypno-Reiki, Nina Rehzats & Teresa Figueroa on Quantum Healing, Suzy Prudden on Making Money on Dr. Carol Francis Radio Show
8. Eldon James Highlights Eco-Friendly Tubing and Fitting Assemblies at MedTec Europe
9. A-lign Senior Consultant James McAllister Receives QSA Certification
10. Complete Currency Trader: Review Of James Edward's Advanced Forex Trading Course Released
11. Brain researcher James Poulet receives the 2013 Paul Ehrlich Prize for Young Researchers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... Leelanau Peninsula’s newest winery, Aurora Cellars ... 7788 East Horn Road in Lake Leelanau. Joining the Northern ... Cellars is the 25th winery along the trail. The winery ... tour events, making its trail event debut during the Harvest ... Owners David and Faye Mathia opened the boutique winery in ...
(Date:7/31/2014)... July 31, 2014 Ce-Classes.com has announced ... course for healthcare professionals, a Systematic Review of ... material published in the International Journal of Clinical and ... in response to a need to have accurate information ... the best treatment possible. The material provides a ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 In today’s world, ... difficult to get. Snoring and sleep apnea (a medical problem ... people and their bed partners of the rest they need ... of the population snores and 20 million people in the ... have been diagnosed and treated; and of those treated, many ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 The vineyards are ... the upcoming harvest. And, to celebrate, folks are gearing up ... Sunday, September 6 and 7, 2014 along the Leelanau ... an optional walk or run through the vineyards start-ing at ... Suttons Bay. A unique course between rows of grapevines offers ...
(Date:7/31/2014)... United Theological Seminary is pleased to welcome ... and Peter J. Bellini. Both began their teaching duties ... a Director of Non-Degree Programs, Mark Abbott, who begins ... Donne, Assistant Professor of New Testament, received a Ph.D. ... Second Temple Judaism, and Greek courses. His research interests ...
Breaking Medicine News(10 mins):Health News:Aurora Cellars Joins the Leelanau Peninsula Wine Trail 2Health News:Company Provides New Course on Sexual Satisfaction 2Health News:Company Provides New Course on Sexual Satisfaction 3Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Leelanau Peninsula’s Annual Harvest Stompede Offers a Unique Vineyard Course for Walkers, Runners and Wine Tasters 2Health News:Growing Seminary Welcomes New Faculty 2
... type of disease, that requires insulin injections daily. Researchers ... this disease. Some medical research centers in the U.S. ... I diabetes by transplanting insulin-producing islet cells combined with ... live normal lives without insulin. , ...
... come up with a new technique of removing cancerous ... their hands and a special camera and instuments. This ... in significantly less time than the standard laproscopic procedure. ... of the American Urological Association by surgeons from the ...
... new gene which has the ability to slow down ... millions of people each year, and luckily tthe discovery ... the cancer of the colon, prostate,pancreas,brain and bowel. ... to stunt the cancer by starving the tumour ...
... from Mayo Clinic brings more choice in eating heath food// ... into any weight loss diets that restrict choices in food. ... the report that talks of sustainable eating habits that help ... weight requires a long-term commitment to making lifestyle changes. However, ...
... Researchers from UCLA had reported in the recent issue ... sleep suffer from loss of brain cells due to ... apnea, the person stops breathing during the sleep when ... in the brain as preB?tzinger complex (preB?tC), which is ...
... and its function has always left man dazzled for ... key factors// have been identified that could answer the ... babies and hence help treat prematurity. ,Identification ... brain damage repair in neurological diseases like multiple sclerosis ...
Cached Medicine News:Health News:Transplant helps diabetes 2Health News:Making operation and recovery time shorter 2Health News:New Healthy Weight Program Makes Healthy Eating More Interesting 2Health News:Sleep Apnea Related To Death And Loss Of Brain Cells 2Health News:Hyaluronic Acid – A Boon To The Problem Of Premature Infant 2
(Date:7/31/2014)... , July 31, 2014 Hovione ... Ireland has successfully passed a pre-approval inspection by ... inspection, carried out by the FDA Consumer Safety Officer, Ms. ... started on 21 st July and concluded on the ... compliant with the principles and guidelines of Good Manufacturing Practices ...
(Date:7/31/2014)... 31, 2014 Catylix, Inc. ( ... Milpitas, California ) announced today the ... commercialize new fluorination products and related chemistry. ... from the use of substituents that are chemically ... polarity to improve binding and bioavailability. Fluorinated functional ...
(Date:7/31/2014)... , July 31, 2014 AFFiRiS AG ... York results of AFF008, a Phase I clinical ... the first therapy against the protein alpha-synuclein, a promising Parkinson,s ... J. Fox Foundation for Parkinson,s Research (MJFF) supported the study ... press conference on the impact a disease-modifying therapy would have ...
Breaking Medicine Technology:Successful FDA Inspection at Hovione's API Manufacturing Plant in Cork, Ireland 2Catylix, Inc. and Aspira Scientific Announce Joint Venture to Commercialize New Fluorination Technologies 2First Clinical Data of Therapeutic Parkinson's Disease Vaccine Encourages Continued Development 2First Clinical Data of Therapeutic Parkinson's Disease Vaccine Encourages Continued Development 3First Clinical Data of Therapeutic Parkinson's Disease Vaccine Encourages Continued Development 4
... in a Single Pill to Target Three Major ... Next Phase of Development, ABBOTT PARK, Ill. and ... will advance the development of,Abbott,s next-generation fenofibrate ABT-335 and ... Phase III,clinical trials. The single pill would target all ...
... Aug. 30 ,Palatin Technologies, Inc. (Amex: PTN ... announced today that they have delayed plans for ... a first in class,melanocortin agonist drug candidate, for ... follows responses from representatives of,the U.S. Food and ...
Cached Medicine Technology:Abbott and AstraZeneca Announce Selection of Next-Generation Fenofibrate ABT-335 and CRESTOR(R) Fixed-Dose Combination 2Abbott and AstraZeneca Announce Selection of Next-Generation Fenofibrate ABT-335 and CRESTOR(R) Fixed-Dose Combination 3King Pharmaceuticals and Palatin Technologies Delay Immediate Plans for Phase 3 Clinical Program With Bremelanotide for Erectile Dysfunction 2
... Final Flexion Wraps restore full PIP joint ... when lost due to arthritic changes. Unparalleled ... material hugs the finger to prevent slipping ... motion. One size. Sold in packages of ...
One splint does it all....
... of minor knee pain like arthritis, tendonitis ... with the motion of the knee, applying ... tendon and assisting in the relief of ... with high density foam padding molds itself ...
... braces are designed to provide comfortable stabilization ... and versatile, ROM braces are an easy ... The braces are extremely patient-friendly, too. , ... hinges that allow you to restrict extension ...
Medicine Products: