Navigation Links
New study suggests stem cells sabotage their own DNA to produce new tissues
Date:2/15/2010

ogrammed cell death. When they blocked this DNA-cutting protein, they also blocked muscle development. They also showed that when the DNA cutting occurs at a key gene known to promote muscle development, it activates that gene and induces the development of new muscle.

"Our research suggests that when a gene is damaged, it can actually increase the expression of that gene, as long as the damage is repaired quickly. This is a novel way for a gene to become activated," says Dr. Megeney. "We've shown that this process is crucial for the development of new muscle tissue, but we believe it may be important for the development of most other tissues as well."

The discovery has important implications for a number of areas. It could help researchers develop better ways to activate stem cells, so that they can produce new tissues for therapeutic purposes. It also suggests that DNA mutations, which can contribute to a variety of diseases, may initially occur as a result of a normal cellular process. And it has implications for researchers developing therapies that inhibit programmed cell death, suggesting that such therapies may also inhibit normal tissue development.


'/>"/>

Contact: Jennifer Paterson
jpaterson@ohri.ca
613-798-5555 x73325
Ottawa Hospital Research Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2015)... ... August 29, 2015 , ... The popular television program VOICES ... recently announced that it will be devoting an entire short segment to the subject ... people around the globe on a daily basis, but recent advancements in medical science ...
(Date:8/28/2015)... Las Vegas, Nevada (PRWEB) , ... August 28, 2015 , ... ... is announcing its decision to make the purchase of CPAP equipment more affordable by ... This offer includes all types of CPAP products and orders of any size. My ...
(Date:8/28/2015)... , ... August 28, 2015 , ... With the goal ... returned for the second year to the Adams County Fairgrounds in Mendon, IL on ... to raise money to support music education in the underfunded school districts of Mendon ...
(Date:8/28/2015)... ... ... The 6th Annual Survivor in the City, Chicago silent auction and cocktail ... its cadre of widespread support—an official letter of support and gratitude from the Mayor ... and the University of Illinois at Chicago’s Department of Neurosurgery, the Brain Aneurysm Foundation ...
(Date:8/28/2015)... ... , ... “ Frequentz ” was featured on NewsWatch as part of its ... market for iOS, Android, and Windows. Joe Toohey, the host of AppWatch and technology ... to track product movement from beginning to end. , Businesses benefit greatly from having ...
Breaking Medicine News(10 mins):Health News:My Cpap Store Now Offering Delivery Special 0 Cost to You 2Health News:Best Drug Rehabilitation Interviews Country-Rock Duo Highway Run at the 2015 "Music With A Mission" Benefit Concert 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Track Product Movement from Beginning to End with Frequentz 2
... Philadelphia, PA, 6 April 2010 - Attention-deficit/hyperactivity disorder (ADHD) ... affecting children and adolescents. Children with ADHD are excessively ... and in school. Problems inhibiting behavior are a common ... treated with stimulant medications, behavioral approaches or a combination ...
... ... to promote organic seed research and conserve crop genetic diversity – ultimately ensuring a ... ... The CLIF BAR Family Foundation today announced a $500,000 grant to promote organic seed ...
... more children today are surviving cancer than ever before, young ... a decade less, on average, than the general population, according ... School of Public Health. Depending on the type of ... years to more than 17 years, the scientists report in ...
... from the Department of Exercise and Sports Sciences, University ... involving both men, women and children, who were divided ... the studies are so remarkable that the Scandinavian ... publishing a special edition issue entitled "Football for Health" ...
... 65 percent in U.S., study finds , TUESDAY, April ... intentional abuse of prescription sedatives, tranquilizers and other painkilling ... research reveals. , Hospital stays from an unintentional overdose ... (such as Valium and Ativan) jumped 37 percent between ...
... ... III in Webinar Series on Opportunities for Improvement in Various Stages of the RN ... ... human capital research firm, will host a webinar titled “When Engagement Isn’t Enough: Retaining ...
Cached Medicine News:Health News:Synergy between behavioral and pharmacologic interventions for ADHD 2Health News:CLIF BAR Family Foundation Commits $500,000 to Protect and Promote Organic Seed and Farming 2Health News:Childhood cancer survivors may face shortened lifespan, study reveals 2Health News:Childhood cancer survivors may face shortened lifespan, study reveals 3Health News:Childhood cancer survivors may face shortened lifespan, study reveals 4Health News:Scientists: Soccer improves health, fitness and social abilities 2Health News:Scientists: Soccer improves health, fitness and social abilities 3Health News:Scientists: Soccer improves health, fitness and social abilities 4Health News:Prescription Drug Abuse Sending More to Hospitals 2Health News:Prescription Drug Abuse Sending More to Hospitals 3Health News:Morehead Presents Webinar on ,“When Engagement Isn't Enough: Retaining RNs”, 2
(Date:8/28/2015)... Company plc ("Perrigo") (NYSE: PRGO ; TASE) today ... OTC brands from GSK in an all cash transaction ... demonstration of Perrigo,s unique ability to maximize brand value ... countries.  Perrigo Chairman, President and CEO ... to complete this transaction, which clearly demonstrates our ability ...
(Date:8/28/2015)... India , August 28, 2015 ... Oils), Livestock (Pork/Swine, Poultry, Ruminant, and Aquaculture), & by Region ... , Asia-Pacific , and Rest of the ... MarketsandMarkets, The global market for Eubiotics was valued at USD ... 7.05 Billion by 2020, at a CAGR of 7.4% from ...
(Date:8/27/2015)... Aug. 27, 2015  The Academy of Managed ... Drug Administration,s (FDA,s) draft guidance and proposed rule ... biosimilars, to bear a nonproprietary name with an ... seeking a decision from the FDA on the ... care stakeholders urging the agency to use the ...
Breaking Medicine Technology:Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 2Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 3Perrigo Completes Acquisition of Leading Portfolio of OTC Brands from GSK 4Eubiotics Market Worth 7.05 Billion USD by 2020 2Eubiotics Market Worth 7.05 Billion USD by 2020 3Eubiotics Market Worth 7.05 Billion USD by 2020 4Eubiotics Market Worth 7.05 Billion USD by 2020 5AMCP Is Disappointed in FDA's Draft Guidance and Proposed Rule Calling for Suffix on Nonproprietary Names of Biological Products 2
... September 6, 2011 The Dutch biotech ... development company Clavis Pharma ASA (Clavis) disclosed signing a ... expression biomarkers for selection of individual Acute Myeloid Leukemia ... drug in development at Clavis. This drug, elacytarabine, is ...
... PROVIDENCE, N.J., Sept. 6, 2011 Advanced Health ... and commercial compliance management solutions for the pharmaceutical ... Senior Vice President & Chief Financial Officer, effective ... financial experience spanning multiple industries including technology solutions, ...
Cached Medicine Technology:Skyline Diagnostics and Clavis Pharma to Collaborate on Patient Selection Biomarker Discovery for Leukemia Drug elacytarabine 2Advanced Health Media, Inc. Announces New CFO 2
... a FAM-labeled probe that is designed to detect ... In addition, this ASR contains primers, a Texas ... sequence. This ASR requires an instrument that can ... as the Cepheid SmartCycler System. The Cepheid Analyte ...
... SpideRX Embolic Protection Device features the ability ... cross the lesion and a pre-loaded nitinol ... and recovery. Offering a fully rapid exchange ... use in the indicated applications:, Carotid Indication ...
Pefakit PiCT DxS Diluent for Determination of Total Heparin...
Controls for APC Resistance / Factor V Leiden Functional Assay...
Medicine Products: