Navigation Links
New drug shows promise against multiple sclerosis
Date:11/1/2011

a remarkable finding," said Stephen Hauser, MD, the Robert A. Fishman Distinguished Professor and Chair of the Department of Neurology at UCSF who was the senior author on the study. "This is extremely exciting, both in terms of the prospect of improved therapy for people with multiple sclerosis but also for the lessons that it teaches us about the fundamental cause of the disease."

"The prospect of an extremely effective therapy for multiple sclerosis that can be safely administered at six month intervals could represent a major step forward, if the safety profile and benefits are sustained over longer periods of use," he added.

At 24 weeks, serious adverse events were reported in 4 percent of patients in the placebo arm, 4 percent of those taking interferon, and 2 percent and 6 percent of patients taking 600 mg and 2000 mg of Ocrelizumab. One patient taking Ocrelizumab died, but the relationship with the study drug, if any, is as yet unclear.

Hauser said that the next step for the drug will be to see if the drug's effect and positive safety profile will be sustained over time. These questions will be addressed in two parallel Phase 3 trials, now enrolling a larger number of patients who will receive the drug regimens for a longer period of time. This trial is now underway at several hundred sites around the world. Hauser serves as lead investigator for these trials, which are sponsored by Roche, the company that owns Ocrelizumab.

What the Trial Suggests About Multiple Sclerosis

Besides the obvious question of whether the drug would work, also under scrutiny in the clinical trial was whether a drug like Ocrelizumab would work in the first place. Its mechanism of action is fundamentally different than other existing therapies for multiple sclerosis. All multiple sclerosis drugs work by targeting a person's immune system only they target fundamentally different parts.

In multiple sclerosis, a person's im
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Preterm birth rate shows three year improvement in most states
2. Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
3. Novel approach to treat proliferative vitreoretinopathy shows promise
4. New therapy shows promise for treating cardiovascular disease
5. More Evidence Shows Newer Forms of Pill Raise Clot Risk, FDA Says
6. New oncolytic virus shows improved effectiveness in preclinical testing
7. Clinical trial shows first evidence that anal cancer is preventable
8. Through-the-nipple breast cancer therapy shows promise in early tests
9. Compound found in common wart treatment shows promise as leukemia therapy
10. Study shows why underrepresented men should be included in binge eating research
11. HIV Medication Patch Shows Promise in Early Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... AidJoy is delighted to announce that it ... on September 5, 2014 from 7:00 to 11:00 p.m. ... expected to attend this semi-formal event. , "We are elated ... six years," says Jess Dennis, Director of Operations and organizer ... this moment in AidJoy’s history before we launch into our ...
(Date:7/23/2014)... The European Bio fertilizers Market Report ... with analysis and forecast of revenue. The bio fertilizers ... $ 2,566.4 million in 2012 to $4,582.2 million by ... 2017. , Browse through the TOC of the European ... the in-depth analysis provided. , http://www.micromarketmonitor.com/market/europe-bio-fertilizer-4637178345.html ...
(Date:7/23/2014)... "I wanted a better way to keep track of all ... pressure and pulse rate," said an inventor from Long Beach, ... a bunch of different devices, so I invented one that ... to make it easier to monitor health conditions. The invention ... enables the user to have more control over his or ...
(Date:7/23/2014)... 2014) Statins, a class of drugs commonly used ... of developing Barrett,s esophagus, according to a new study ... official journal of the American Gastroenterological Association. Obese patients ... use. , "Patients who received statins had a 43 ... compared to non-users," said study author Hashem B. El-Serag, ...
(Date:7/23/2014)... some high-profile athletes who suffered repeated blows to the ... their brains. Those clumps suggest the athletes had a ... working on tests that might be able to detect ... in Chemical & Engineering News (C&EN) , the ... In the article, Lauren Wolf, a senior editor at ...
Breaking Medicine News(10 mins):Health News:AidJoy’s Inaugural Gala to be Held September 5, 2014 2Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 2Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 3Health News:Europe Bio Fertilizer Market is Expected to Reach $4,582.2 Million in 2017 - New Report by MicroMarket Monitor 4Health News:Statin use decreases the risk of Barrett's esophagus 2
... Oct. 15 (HealthDay News) -- Women in their 40s who are ... for having mammograms to 50 may find clarity in a new ... save lives. "The bottom line is everyone over the age ... chief of breast imaging at Lenox Hill Hospital in New York ...
... higher intake of alcohol during pregnancy adversely affects the ... other problems in the child. However, most recent ... light drinking by the mother during pregnancy. The ... factors of the mother may have large effects on ...
... prodigious precursors of all the tissues in our body, ... unfortunately, cancer. Now research from Rockefeller University shows that ... live for too long, can increase the odds of ... cell death in precursor cells for blood, or hematopoietic ...
... Jenifer Goodwin HealthDay Reporter , THURSDAY, Oct. 14 ... may help alleviate the symptoms of fibromyalgia, a small study ... syndrome, were enrolled in a two-hour yoga class that met ... women diagnosed with the condition were put on a waiting ...
... Gardner HealthDay Reporter , THURSDAY, Oct. 14 ... of lovelorn Stanford undergrads, researchers discovered that high-octane romantic ... effect isn,t just that the person is distracted by ... too. Instead, the researchers found that feeling "head-over-heels" activates ...
... is available in Spanish . Researchers a ... Nuclear Medicine, Hospital Virgen de las Nieves at Granada found ... of a structural analog of glucose labeled with a positron-emitting ... relatively rare disease with high mortality rates among most patients ...
Cached Medicine News:Health News:Latest Findings Back Mammograms for Women in Their 40s 2Health News:Latest Findings Back Mammograms for Women in Their 40s 3Health News:2 studies present new data on effects of alcohol during pregnancy 2Health News:Gene identified that prevents stem cells from turning cancerous 2Health News:Gene identified that prevents stem cells from turning cancerous 3Health News:Yoga May Combat Fibromyalgia Symptoms 2Health News:Yoga May Combat Fibromyalgia Symptoms 3Health News:Yoga May Combat Fibromyalgia Symptoms 4Health News:Romantic Love: Nature's Painkiller? 2Health News:Romantic Love: Nature's Painkiller? 3Health News:New method is found for accurate diagnosis of gall bladder cancer, 1 of the most deadly 2
(Date:7/23/2014)... -- The Centers for Medicare & Medicaid Services (CMS) ... Organization (QIN-QIO) contract to a partnership led by the ... 1, WVMI will launch Quality Insights Quality Innovation Network ... Pennsylvania , Delaware , ... will engage providers and the community in multiple, data-driven ...
(Date:7/23/2014)... 2014 Research and Markets   ... Electrophysiology Ablation Catheters Market 2014-2018" report to ... Catheter ablation is a minimally ... electrical pathways from sections of the heart that ... arrhythmias). Cardiac arrhythmias can be of several types, ...
(Date:7/23/2014)... -- Creekridge Capital, an independent vendor-focused finance company, ... far in 2014 to their portfolio of contractual ... both the healthcare and technology industries. They range ... companies. Each of these new vendors take advantage ... standard leasing products, subscription solutions, a dedicated revolving ...
Breaking Medicine Technology:Announcing a New Regional Approach to Medicare Quality Improvement 2Global Electrophysiology Ablation Catheters Market 2014-2018: Key Vendors are Boston Scientific, Johnson & Johnson, Medtronic and St. Jude Medical 2Global Electrophysiology Ablation Catheters Market 2014-2018: Key Vendors are Boston Scientific, Johnson & Johnson, Medtronic and St. Jude Medical 3Creekridge Capital Signs Several New Vendor Partners 2
... Sigma-Aldrich (Nasdaq: SIAL ) announced today that it ... leader in bench top flow chemistry instruments, the terms ... of approximately 400 CatCart® catalyst products for flow chemistry ... and CatCart catalyst cartridges provide organic chemists in academic ...
... Accumetrics, Inc., developer and marketer of the VerifyNow® ... measuring an individual,s response to multiple antiplatelet agents, announced ... that will raise $16.5 million in new capital. ... into 2011, came from the company,s existing investors, including ...
Cached Medicine Technology:Sigma-Aldrich(R) Partners With Flow Chemistry Leader ThalesNano to Provide CatCart(R) Catalyst Products for Rapidly Growing Market 2Sigma-Aldrich(R) Partners With Flow Chemistry Leader ThalesNano to Provide CatCart(R) Catalyst Products for Rapidly Growing Market 3Accumetrics Announces $16.5M in New Capital Financing 2Accumetrics Announces $16.5M in New Capital Financing 3
Surgical Stainless Steel Adult 16.5....
Ultra-Slip™ endotracheal tube guide for single-patient use only., ,Caution: Not MRI Compatible....
FlexiSlip™ Plastic coated malleable metal core. Single use, Sterile, Latex Free. Soft distal tip flexes to reduce risk of trauma to patient. Malleable metal core is easy to shape. Low friction ...
FlexiSlip™ Plastic coated malleable metal core. Single use, Sterile, Latex Free. Soft distal tip flexes to reduce risk of trauma to patient. Malleable metal core is easy to shape. Low friction ...
Medicine Products: