Navigation Links
New drug shows promise against multiple sclerosis
Date:11/1/2011

a remarkable finding," said Stephen Hauser, MD, the Robert A. Fishman Distinguished Professor and Chair of the Department of Neurology at UCSF who was the senior author on the study. "This is extremely exciting, both in terms of the prospect of improved therapy for people with multiple sclerosis but also for the lessons that it teaches us about the fundamental cause of the disease."

"The prospect of an extremely effective therapy for multiple sclerosis that can be safely administered at six month intervals could represent a major step forward, if the safety profile and benefits are sustained over longer periods of use," he added.

At 24 weeks, serious adverse events were reported in 4 percent of patients in the placebo arm, 4 percent of those taking interferon, and 2 percent and 6 percent of patients taking 600 mg and 2000 mg of Ocrelizumab. One patient taking Ocrelizumab died, but the relationship with the study drug, if any, is as yet unclear.

Hauser said that the next step for the drug will be to see if the drug's effect and positive safety profile will be sustained over time. These questions will be addressed in two parallel Phase 3 trials, now enrolling a larger number of patients who will receive the drug regimens for a longer period of time. This trial is now underway at several hundred sites around the world. Hauser serves as lead investigator for these trials, which are sponsored by Roche, the company that owns Ocrelizumab.

What the Trial Suggests About Multiple Sclerosis

Besides the obvious question of whether the drug would work, also under scrutiny in the clinical trial was whether a drug like Ocrelizumab would work in the first place. Its mechanism of action is fundamentally different than other existing therapies for multiple sclerosis. All multiple sclerosis drugs work by targeting a person's immune system only they target fundamentally different parts.

In multiple sclerosis, a person's im
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Preterm birth rate shows three year improvement in most states
2. Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
3. Novel approach to treat proliferative vitreoretinopathy shows promise
4. New therapy shows promise for treating cardiovascular disease
5. More Evidence Shows Newer Forms of Pill Raise Clot Risk, FDA Says
6. New oncolytic virus shows improved effectiveness in preclinical testing
7. Clinical trial shows first evidence that anal cancer is preventable
8. Through-the-nipple breast cancer therapy shows promise in early tests
9. Compound found in common wart treatment shows promise as leukemia therapy
10. Study shows why underrepresented men should be included in binge eating research
11. HIV Medication Patch Shows Promise in Early Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota ... it means to “Live Fearless.” , The “Faces ... their stories about how they or someone they know has ... living in the moment. By telling these types of stories ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A new ... of experience and person-centeredness in the long-term care environment ... action across the continuum. The paper, “The Power of ... engages perspectives and practices of the patient, resident and ...
(Date:1/22/2015)... Carinsurancesavings.biz has released a new blog post presenting the ... , Purchasing an accidental death and dismemberment rider for ... of rider provides benefits if the insured dies in an ... form of life insurance. , AD&D is not expensive ...
(Date:1/22/2015)... has added many trendy Champagne wedding dresses to ... the past three years. Today, the business announces a special ... the sales manager of the company, this is on the ... point can be reflected on the discounted wedding dresses from ...
(Date:1/22/2015)... 22, 2015 EBSCO Information Services ... expanding their relationship in an effort to further promote visibility ... While EBSCO has long made AMA journals available via its ... for The JAMA Network. , Long known as ...
Breaking Medicine News(10 mins):Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4
... Janakpur zonal hospital found themselves in peril after doctors ... resignation.// The resignation en masse was submitted on Sunday, ... to doctors – said senior physician Dr Gaurang Mishra. ... and Dr. Raj Kumar Mahoto were beaten up by ...
... a grim fact. Diseases like diabetes, heart conditions,// kidney ... is that fifty per cent of these diseases are ... lifestyle diseases can be avoided by quitting wrong habits ... exercising enough. , “Unless Queenslanders make informed ...
... public. A decade after genetically altered crops were first ... disinclined towards them. ,According to a survey sponsored ... last five years have seen little change in the ... director of the survey’s sponsor, Michael Fernandez, “Americans are ...
... prevalence of infectious diseases like tuberculosis and meningitis in ... on the importance of specialization in such diseases during ... the US, where infectious diseases specialty has been present ... focused upon adequately. The result is while there are ...
... rehabilitation clinic no. 17,faced one of the most deadliest fires that ... //. 45 women were killed because of burns, and smoke asphyxiation. ... of 35.Some were HIV patients and few suffered from severe psychological ... few months ago that the building was not safe ,and ...
... suffer through a range of problems, from poor grades ... than half of these children also have serious problems ... learning to develop the social skills they need to ... with ADHD often are peer-rejected, and their difficulties multiply ...
Cached Medicine News:Health News:Gene-Altered Foods ? Still Not Sure 2Health News:India’s Need for Specialization in Infectious Diseases Urge 2Health News:Friendship Clinic: Psychologist Helps Children With ADHD Make Friends 2Health News:Friendship Clinic: Psychologist Helps Children With ADHD Make Friends 3
(Date:1/22/2015)...  BiOptix is pleased to announce the appointment of Dr. ... and Biochemistry. Scott joins the company after previous scientific leadership ... the course of his nearly 20 year career in ... nationally recognized thought leader in the biosensor field and ...
(Date:1/22/2015)... Inc. (NYSE: RMD ) today announced results for ... was $423.0 million, a 10 percent increase compared to the ... a constant currency basis). Net income was $91.2 million, an ... 31, 2013. Diluted earnings per share for the quarter were ...
(Date:1/22/2015)... Jan. 22, 2015  Amgen (NASDAQ: AMGN ) today announced ... financial results on Tuesday, Jan. 27, 2015, after the close of ... conference call with the investment community at 2 p.m. PT. Participating ... , chairman and chief executive officer, and other members of Amgen,s ...
Breaking Medicine Technology:BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 2ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 3ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 4ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 5ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 6ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 7ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 8ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 9ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 10ResMed Inc. Announces Results for the Second Quarter of Fiscal Year 2015 11Amgen Announces Webcast of 2014 Fourth Quarter and Full Year Financial Results 2
... As the economy recovery continues to lag, employers are ... health care costs. Running counter to these goals, independent ... employers, ability to save money by offering lower cost ... Management Association (PCMA) said today. "As the ...
... Stryker Joint Preservation, a business unit of Stryker,s ... Society for Sports Medicine meeting that it has entered ... Stryker,s RegenKit-THT, a one-step system designed for the safe ... a small sample of blood at the patient,s point ...
Cached Medicine Technology:As Economic Recovery Sputters, Independent Drugstores Shouldn't Shoulder Employers With Higher Costs 2Stryker Announces Exclusive Collaboration With RegenLab 2
It has the near point, Snellen X-CYL Jaeger & SMD cards in one set....
Rosenbaum card fits in the pocket (3.5 by 6.5") and shows point, Jaeger and distance equivalents from 20/800 to 20/20. Uses numbers, directional Es and XO patterns. For use at 14" (35 mm). Includes f...
... This two sided contemporary reading ... as crossword puzzle, schedules for trains, ... quotes, music bars, playing cards, recipes, ... listings, and horse racing listings. Continuous ...
Spanish reading test....
Medicine Products: