Navigation Links
New drug shows promise against multiple sclerosis
Date:11/1/2011

a remarkable finding," said Stephen Hauser, MD, the Robert A. Fishman Distinguished Professor and Chair of the Department of Neurology at UCSF who was the senior author on the study. "This is extremely exciting, both in terms of the prospect of improved therapy for people with multiple sclerosis but also for the lessons that it teaches us about the fundamental cause of the disease."

"The prospect of an extremely effective therapy for multiple sclerosis that can be safely administered at six month intervals could represent a major step forward, if the safety profile and benefits are sustained over longer periods of use," he added.

At 24 weeks, serious adverse events were reported in 4 percent of patients in the placebo arm, 4 percent of those taking interferon, and 2 percent and 6 percent of patients taking 600 mg and 2000 mg of Ocrelizumab. One patient taking Ocrelizumab died, but the relationship with the study drug, if any, is as yet unclear.

Hauser said that the next step for the drug will be to see if the drug's effect and positive safety profile will be sustained over time. These questions will be addressed in two parallel Phase 3 trials, now enrolling a larger number of patients who will receive the drug regimens for a longer period of time. This trial is now underway at several hundred sites around the world. Hauser serves as lead investigator for these trials, which are sponsored by Roche, the company that owns Ocrelizumab.

What the Trial Suggests About Multiple Sclerosis

Besides the obvious question of whether the drug would work, also under scrutiny in the clinical trial was whether a drug like Ocrelizumab would work in the first place. Its mechanism of action is fundamentally different than other existing therapies for multiple sclerosis. All multiple sclerosis drugs work by targeting a person's immune system only they target fundamentally different parts.

In multiple sclerosis, a person's im
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Preterm birth rate shows three year improvement in most states
2. Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
3. Novel approach to treat proliferative vitreoretinopathy shows promise
4. New therapy shows promise for treating cardiovascular disease
5. More Evidence Shows Newer Forms of Pill Raise Clot Risk, FDA Says
6. New oncolytic virus shows improved effectiveness in preclinical testing
7. Clinical trial shows first evidence that anal cancer is preventable
8. Through-the-nipple breast cancer therapy shows promise in early tests
9. Compound found in common wart treatment shows promise as leukemia therapy
10. Study shows why underrepresented men should be included in binge eating research
11. HIV Medication Patch Shows Promise in Early Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... Get ready to sweat. , Automatic ... in conjunction with the Nutrié California Kick Off ... participants will get the chance to work out with ... The Dr. Oz Show, and The Dr. Phil Weight ... the undefeated UFC heavy-weight contender Daniel Cormier at Chukchansi ...
(Date:5/23/2013)... 2013 911 Signal USA is attending the ... on May 22 and run through May 24, 2013. , ... the company's emergency vehicle lights and sirens, 911 ... Charger at the expo. , The Charger has been equipped ... and can be seen by visiting 911 Signal USA during ...
(Date:5/23/2013)... Woburn, MA (PRWEB) May 23, 2013 ... American made high-grade auto detailing systems , ... truck cleaning systems , as well as other ... across hundreds of nations worldwide, is now offering ... washer designed to help manage a myriad of ...
(Date:5/22/2013)... 23, 2013 MileageAds.com, an American based ... to companies in the Stocks and Bonds Sector to ... to advertise with MileageAds will have the opportunity to ... , Stocks and bonds companies who accept Mileageads.com’s invitation ... of a specific, targeted audience on the ...
(Date:5/22/2013)... (PRWEB) May 23, 2013 Catalyst Exhibits, ... a new feature to its website that ... agency’s client portfolio through an immersive, 360-degree, interactive experience. ... prospective customers the ability to virtually experience the exhibit ... of medical technologies and services. Users have the ability ...
Breaking Medicine News(10 mins):Health News:Kim Lyons, Gunter Schlierkamp, & Daniel Cormier To Host Fresno Charity Workout 2Health News:Kim Lyons, Gunter Schlierkamp, & Daniel Cormier To Host Fresno Charity Workout 3Health News:911 Signal USA Attends the 2013 Southwest Police Fleet Expo 2Health News:Commercial Pressure Washer Debuted By Daimer Industries For Wheelchair Cleaning 2Health News:Commercial Pressure Washer Debuted By Daimer Industries For Wheelchair Cleaning 3Health News:Commercial Pressure Washer Debuted By Daimer Industries For Wheelchair Cleaning 4Health News:Mileageads.com Ad Network Now Invites Companies in Stocks and Bonds Services Sector to Advertise on Their Ad Network 2Health News:Catalyst Exhibits Debuts 360 Degree Virtual Tour of St. Jude Medical Trade Show Booth 2
... Gujarat Health Minister Ashok Bhatt was admitted to ... morning after he complained of chest pain, hospital ... to the cardiology hospital at the Civil Hospital ... Minister had undergone angioplasty test for a heart ...
... Tumda (a 4 year old girl) lies in a hospital bed ... of tender skin that hang from her body//. ,Her ... from a bony frame (a classical sign of malnutrition) was seen. ... girl in the western state of Maharashtra, just 125 km (80 ...
... the very popular belief that people who have suffered from ... grow up, a new study reports// that they in reality ... knocks make gullible adults; this was the finding of a ... that the people who suffered from troubled upbringing during childhood ...
... A new study suggests that people preparing for surgery needs ... who warmed up by playing video games// like ‘Super Monkey ... were faster and made fewer errors than those who did ... a medical training course that included video games and was ...
... Pharmaceuticals and Chemicals Ltd today said it will ... Inc for 74.5 million dollars. // ... 100 per cent stake in CarboGen and Amcis--Solutia ... statement., ,The acquisition includes other assets used ...
... growing problems due to use of drugs in northeastern ... today suggested effective monitoring // and reporting systems in ... need to establish effective drug use monitoring and reporting ... said while releasing a monograph on the drug use ...
Cached Medicine News:Health News:India's Economic Boom Pack To Waste Children Life 2
(Date:5/22/2013)... 22, 2013  Viral hepatitis is an asymptomatic disease affecting ... those with hepatitis C are unaware they have the virus. ... Day in the U.S. House of Representatives will take place ... of the Rayburn House Office Building in Washington, ... the Study of Liver Diseases ( AASLD ) is pleased ...
(Date:5/22/2013)... -- The Lupus Research Institute (LRI) today is hosting the ... lupus nephritis, a serious kidney complication of lupus affecting ... a new international alliance of researchers specializing in lupus ... More than 50 of the world,s top experts ... on two critical questions: 1) Which new medicines have ...
(Date:5/22/2013)... CENTER, Ohio , May 22, 2013 /PRNewswire/ ... Opioid Defense Manager™ (ODM).  Launched in November 2012 ... revolutionary managed care program to stop the rising ... is a proactive, customized program designed to protect ... use while maintaining the necessary balance to provide ...
Breaking Medicine Technology:Hepatitis Awareness: Bringing Attention to a Silent Epidemic 2Lupus Research Institute Hosts First International Conference to Advance New Treatments for Lupus Nephritis 2Modern Medical Introduces Opioid Abuse Solution to the Workers' Compensation Industry 2
... GORE-TEX Stretch Vascular Grafts have met ... vascular procedures. Recognized for exceptional performance ... endorsement of renowned surgeons worldwide. These ... and the spread of infection, and ...
... GORE-TEX INTERING Vascular Graft, the newest vascular ... Associates, a leader in vascular surgical products ... performance by reducing kinking and compression ... This new graft provides all of the ...
... GORE-TEX INTERING Vascular Graft, the newest vascular ... Associates, a leader in vascular surgical products ... performance by reducing kinking and compression ... This new graft provides all of the ...
... EpochXP Workstations provide comprehensive neurological monitoring ... care unit to accurately access your ... over 15 years experience, and a ... EpochXP neurological monitoring systems have a ...
Medicine Products: