Navigation Links
New drug shows promise against multiple sclerosis
Date:11/1/2011

An experimental drug called Ocrelizumab has shown promise in a Phase 2 clinical trial involving 220 people with multiple sclerosis (MS), an often debilitating, chronic autoimmune disease that affects an increasing number of people in North America. It usually strikes young adults and is more common in women than in men.

The study, carried out by researchers at the University of California, San Francisco (UCSF) Medical Center, and involving hospitals in the United States, Canada, and Europe, is described this week in the British medical journal Lancet.

The study involved patients with relapsing-remitting MS, a form of the disease marked by the accumulation of lesions in the brain and spinal cord and periodic "attacks" of neurological impairment.

The 220 patients were randomly enrolled into four groups two that received injections of the monoclonal antibody Ocrelizumab at two different doses, one that received the standard multiple sclerosis drug interferon-beta, and one "control" group that was given a placebo.

The doctors gauged the effectiveness of each treatment by performing monthly magnetic resonance imaging (MRI) brain scans of the patients and counting the number of visible marks that indicate inflamed lesions, a hallmark of the disease. They also compared the severity and frequency of neurological "attacks" that cause loss of vision, incoordination, weakness and numbness, among other symptoms.

The results of this trial showed that patients who received the drug generally fared well and showed fewer signs of the disease than patients who receive a placebo or the standard Interferon treatment. Overall, the trial found that Ocrelizumab led to a 89 percent reduction in the formation of brain lesions, and it also reduced the number of new multiple sclerosis attacks over 24 weeks. During this relatively short-term study, interferon performed no better than placebo on these outcomes.

"It really is
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related medicine news :

1. Preterm birth rate shows three year improvement in most states
2. Study shows no increased risk of breast cancer for non-carriers in families with BRCA gene mutation
3. Novel approach to treat proliferative vitreoretinopathy shows promise
4. New therapy shows promise for treating cardiovascular disease
5. More Evidence Shows Newer Forms of Pill Raise Clot Risk, FDA Says
6. New oncolytic virus shows improved effectiveness in preclinical testing
7. Clinical trial shows first evidence that anal cancer is preventable
8. Through-the-nipple breast cancer therapy shows promise in early tests
9. Compound found in common wart treatment shows promise as leukemia therapy
10. Study shows why underrepresented men should be included in binge eating research
11. HIV Medication Patch Shows Promise in Early Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... @the_USO & @SesameStreet are proud to kick-off ... the next 6 months! , Today, the ... together to show their heartfelt thanks to those who currently serve ... distribution to our servicemen and women. The group was also ... the USO as well as the success of the Sesame ...
(Date:5/22/2013)... Nearly 50,000 veterans appeals were received by ... 2012, with even more—54,033—expected by fiscal year-end 2013. However, ... as the agency reports reduced decisions and a reduced ... appeal services. The BVA is an agency of ... BVA received 49,611 cases in FY 2012, it reached ...
(Date:5/22/2013)... HealthDay Reporter , , WEDNESDAY, May 22 (HealthDay News) ... are more likely to attempt suicide, whether or not ... according to a new study. "Clinicians who are ... they are at increased risk of suicide," said study ... Illness Treatment Resource and Evaluation Center in Ann Arbor, ...
(Date:5/22/2013)... 22, 2013 Bodybuilding.com is giving ... (May 27, 2013) Bodybuilding.com will be donating $1 from EVERY ... , “We are extremely grateful for the men and ... said Ryan DeLuca, CEO and founder of Bodybuilding.com. “It’s an ... sacrificed so much. Hire Heroes USA is an amazing organization ...
(Date:5/22/2013)... 22, 2013 Today, Zane Benefits, Inc. ... Insurance Exchange . Zane Benefits, which provides comprehensive and ... the leader in defined contribution plans and ... Benefits’ website, beginning in 2014 as part of the ... and small businesses will become available through new state ...
Breaking Medicine News(10 mins):Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 2Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 3Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 4Health News:The USO and Sesame Street Announce Spring Kick Off of World Tour at Biannual Care Package Service Project Event in DC 5Health News:Veterans Disability Appeals See Fewer Decisions in FY2012, Reports Allsup 2Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 2Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 3Health News:In the Spirit of Memorial Day, Bodybuilding.com is Donating a Portion of Their Sales to Hire Heroes 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 2Health News:Zane Benefits Publishes New Information on Alabama Health Insurance Exchange 3
... at Capitol to meet with legislators LANSING, Mich., May ... childhood investment supporters are expected at the Capitol Thursday, ... our youngest citizens is critical to Michigan,s economic future.It ... began in 2007."This issue is more important than ever ...
... announced today that it is making a $10,000 donation ... in the Santa Barbara area who have been impacted by ... In addition, Anthem announced today several additional actions it is ... Anthem Blue Cross members may have left ...
... May 8 Bertalan Mesko, medical blogger and health ... collections featuring medical and scientific videos and animations. ... from the best quality. Some of the sites are ... reliable videos focusing on health issues, while others were ...
... more likely to experience complications, study finds , , FRIDAY, ... likely than any other racial group to suffer serious ... procedures, but the reasons for these worse outcomes aren,t ... included 1,410 patients, average age 57, who had a ...
... May 8 The majority of uninsured American families ... an employer cannot afford to buy health insurance, according ... Research and Quality.Some experts have suggested that because 23.8 ... have access to employer-based health insurance have incomes above ...
... Free Student Memberships Now Available on Online Community ... Medical Device TechnologiesFERNANDINA BEACH, Fla., May 8 ... just a few short weeks since launch, e-Zassi.com ... medical device industry participants involved in the discovery, ...
Cached Medicine News:Health News:Early Childhood Funding is Focus of Star Power Event 2Health News:Anthem Blue Cross to Support Members and Communities Impacted by Santa Barbara Fires 2Health News:Racial Disparity Seen in Angioplasty Outcomes 2Health News:New Study Finds Fewer Families Can Afford Health Insurance 2Health News:New Advanced Search and Matching Function Drives e-Zassi.com's Enhanced Functionality 2
(Date:5/22/2013)... RALEIGH, N.C. , May 22, 2013 ... pleased to announce the launch of their web site ... reports [STEPh Reports].  About STEPh Reports ... drugs in development.  Each STEPh Report ... clinical trials data, projected launch year, company, and specific ...
(Date:5/22/2013)... , May 22, 2013 Hemoglobin ... commercially-insured patients with Type 2 diabetes, while modest ... improve health outcomes and can lead to substantial ... at the International Society for Pharmacoeconomics and Outcomes ... The two studies, sponsored by Valeritas, makers of ...
(Date:5/22/2013)... and TORONTO , May ... (OTCBB: GNBT) today announced three presentations demonstrating the superiority ... its wholly-owned subsidiary, Antigen Express, Inc. ( www.antigenexpress.com ). ... of the American Society of Clinical Oncology (ASCO) to ... May 31 through June 4, 2013. The ...
Breaking Medicine Technology:Scientific and Technical Evaluation of Pharmaceuticals, Inc. [STEPh, Inc.], Launches New Competitive Intelligence Web Site 2Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 2Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 3Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 4Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 5Type 2 Diabetes Control Worsening, According To Study Of Patients On Commercial Insurance 6Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 2Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 3Generex Announces ASCO Presentations on the Antigen Express Advanced Stage AE37 Cancer Vaccine 4
The Skull Pins are inserted into the receptacles of the Skull Clamp and fixate the head during surgery....
Mayfield Disposable Adult (plastic) Skull Pins are designed for rigid skeletal fixation....
Endoscopes...
Short system ventriculoscope for free hand use....
Medicine Products: