Navigation Links
New TB test promises to be cheap and fast
Date:5/22/2012

Biomedical engineers at UC Davis have developed a microfluidic chip to test for latent tuberculosis. They hope the test will be cheaper, faster and more reliable than current testing for the disease.

"Our assay is cheaper, reusable, and gives results in real time," said Ying Liu, a research specialist working with Professor Alexander Revzin in the UC Davis Department of Biomedical Engineering.

The team has already conducted testing of blood samples from patients in China and the United States.

About one-third of the world's population is infected with the bacteria that cause tuberculosis, a disease that kills an estimated 1.5 million people worldwide every year, according to the U.S. Centers for Disease Control and Prevention.

Most infected people have latent TB, in which the bacteria are kept in check by the immune system. Patients become sick only when the immune system is compromised, enabling the bacteria to become active. People with HIV are at especially high risk.

Current tests for latent TB are based on detecting interferon-gamma, a disease-fighting chemical made by cells of the immune system. Commercially available tests require sending samples to a lab, and can be used just once.

Liu and Revzin used a novel approach: They coated a gold wafer with short pieces of a single-stranded DNA segment known to stick specifically to interferon-gamma. They then mounted the wafer in a chip that has tiny channels for blood samples. If interferon-gamma is present in a blood sample, it sticks to the DNA, triggering an electrical signal that can be read by a clinician.

"If you see that the interferon-gamma level is high, you can diagnose latent TB," Liu said.

The researchers plan to refine the system so that the microfluidic sensor and electronic readout are integrated on a single chip.

A patent application has been filed for the technology, and the researchers hope the test can be commercialized after FDA approval. The work was supported by the National Science Foundation.


'/>"/>
Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
Source:Eurekalert  

Related medicine news :

1. Nuclear physics promises earlier detection of brain tumors with just 1 scan
2. Will Redmond ONeal Fulfill His Mothers Wishes? Promises Addiction Guru Dr. David Sack Weighs In.
3. New Pill Promises to Stop Gray Hair
4. New UC research promises better collection of prostate cancer cells
5. A realistic look at the promises and perils of nanomedicine
6. PET technique promises better detection and response assessment for Non-Hodgkins lymphoma
7. New Moffitt Cancer Center patent promises to accelerate cancer trials
8. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
9. DiscountSupplements.com Launches Website With the Cheapest Supplements Prices and Fastest Shipping
10. Launching New Cloud Server Technologies on Website Hosting and Much Cheaper Web Hosting
11. New pathway to cheap insulin
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New TB test promises to be cheap and fast
(Date:7/4/2020)... ... 2020 , ... MemoryCare.com , a comprehensive resource for ... Care Facilities in Charleston, South Carolina. The guide identifies 5 memory care communities ... to the Alzheimer’s Association , 5.6 million people age 65 and older ...
(Date:7/2/2020)... ... July 02, 2020 , ... Columbia Southern ... of the Year Award to Eric Simmons of Temecula, California. , CSU’s ... Simmons, who holds a master’s degree in occupational safety and health from the ...
(Date:7/1/2020)... ... 2020 , ... Dexur’s analysis of Medicare claims of hospitals within ... Adventist Hospital , and Sky Ridge Medical Center had the best ... analysis tracks a patient’s episode of care from the date of admission for 90 ...
(Date:7/1/2020)... ... 2020 , ... The Society to Improve Diagnosis in Medicine ... University of Massachusetts Medical School- Baystate and Ann Gaffey, RN, MSN, CPHRM, DFASHRM, ... Directors. Dr. Salvador and Ms. Gaffey’s service began in May and the initial ...
(Date:6/28/2020)... ... June 26, 2020 , ... ... to provide high-quality, intensive education and training that prepares graduates for professional careers ... new member of the Board of Trustees. , Ms. Williams currently serves as ...
Breaking Medicine News(10 mins):
(Date:7/2/2020)... ... July 02, 2020 , ... Exercise.com, the fitness industry’s leading ... 913,628,072 lifted pounds were logged through its software during the months of May and ... of fitness – an age where even gym giants like 24 Hour Fitness ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... distributor, is pleased to announce its donation of more than $190,000 in personal ... of Health and Human Services. As extreme medical shortages continue to plague the ...
(Date:7/1/2020)... ... July 01, 2020 , ... Lumeda Inc. (“Lumeda”), ... the formation of its Scientific Advisory Board with the appointment of a panel ... advice to support company development and introduction of its PDT products to the ...
Breaking Medicine Technology: