Navigation Links
New Study Demonstrates Ramelteon Does Not Exacerbate Respiratory Depressant Effects in Patients With Moderate-to-Severe COPD
Date:12/3/2007

a five- to ten-day washout, patients crossed over to the alternate treatment and repeated the procedure.

The primary endpoint was mean SaO2 for the entire night. The findings revealed that there was no statistically significant difference in SaO2 for the entire night observed among the patients treated with ramelteon compared to placebo (92.2 vs. 92.4%, P=0.576). Additional results showed:

-- Compared with placebo, there was no statistically significant

difference in the number of minutes in the night that SaO2 was <80% and

<90% (P=0.927 and P=0.653, respectively).

-- The mean apnea-hypopnea index was similar between ramelteon and placebo

(P=0.804).

-- A significant increase in total sleep time (389.0 vs 348.4 min,

P=0.019) and sleep efficiency (81.0 vs 72.6%, P=0.019) was observed

with ramelteon vs placebo.

-- Latency to persistent sleep was shorter with ramelteon vs placebo (23.1

vs 56.9 min) (P=0.051).

-- Adverse events were reported in four patients with ramelteon and four

patients with placebo treatment; none was noted as serious or led to

study discontinuation.

People with COPD have few options for treating insomnia because the traditional sleep medications cause a sedative effect that can further depress respiration. "This study is important in helping us understand the effects of ramelteon in patients with moderate to severe COPD," said Louis J. Mini, MD, medical director, Neuroscience, Takeda Pharmaceuticals North America, Inc. "COPD is a common disorder seen in clinical practice, and studies of this type provide useful information for physicians treating this population."

About ROZEREM

Ramelteon 8 mg is currently marketed as ROZEREM(TM). ROZEREM is indicated for the treatment of insomnia characterized by difficulty with sleep onset. ROZEREM can be prescribed for long-term use. ROZEREM is the first and only prescription
'/>"/>

SOURCE Takeda Pharmaceuticals North America, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... Twin to twin transfusion syndrome (TTTS) ... before they were born, but an innovative fetal surgery at the ... chance at life. , Now, their parents David and Theresa Colp ... option available in St. Louis at the St. Louis Fetal Care ... Pub House (6655 Delmar Blvd, St Louis, MO 63130) on Friday, ...
(Date:8/31/2014)... Tickets for Brazil vs. Ecuador at MetLife Stadium ... is great news for diehard soccer fans who would have loved ... delight of soccer fans in the Tri-State area these two international ... 9th. , MetLife Stadium is the home field for ... National Football League. The venue opened in 2010 and has already ...
(Date:8/31/2014)... Ticket Down is a dependable source for cheap ... Sun Life Stadium in early September. Diehard soccer fans can ... September 5th between Colombia and Brazil will likely set a new ... Brazil and Honduras at Sun Life Stadium brought in excess of ... also been the home of the Florida Marlins of MLB in ...
(Date:8/31/2014)... UWDress.com, a renowned wedding dress manufacturer and retailer, ... elegant formal bridesmaid dresses today. Moreover, the ... quality special occasion outfits. All its current and prospective ... , Along with the greatly discounted prices, all ... promotional formal bridesmaid outfits are offered in over 20 ...
(Date:8/31/2014)... Recently, iFitDress.com, a well-known wedding dress manufacturer and retailer, has ... for 2014. What’s more, the firm has decided to launch ... can enjoy a low rate (up to 64 percent off) ... until September 12. , “We are happy to unveil ... home and abroad. The main purpose of the big sale ...
Breaking Medicine News(10 mins):Health News:After a Rare Diagnosis Threatened Their Boys’ Lives, Parents Build Awareness About TTTS and Fetal Surgery Options at The SSM St. Louis Fetal Care Institute. 2Health News:After a Rare Diagnosis Threatened Their Boys’ Lives, Parents Build Awareness About TTTS and Fetal Surgery Options at The SSM St. Louis Fetal Care Institute. 3Health News:Brazil vs. Ecuador Tickets MetLife Stadium: Ticket Down Slashes Ticket Prices on Ecuador vs. Brazil Tickets in East Rutherford, NJ at the MetLife Stadium 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for September 5th Match 2Health News:Brazil vs. Colombia Tickets in Miami: Ticket Down Slashes Colombia vs. Brazil Tickets at Sun Life Stadium in Miami for September 5th Match 3Health News:Elegant Formal Bridesmaid Dresses Today Unveiled By UWDress.com 2Health News:Gorgeous Bridesmaid Dresses For 2014 Now Offered By iFitDress.com 2
... & Science University Knight Cancer Institute will evaluate whether ... Wash.) is as effective in delivering highly precise radiation ... has been in those with prostate cancer. , "We ... prostate cancer, and it is our hope to apply ...
... epidemicWASHINGTON, April 28 Transportation Security Officers across the country ... they screen passengers who may have been exposed to the ... an urgent letter to TSA Acting Administrator Gale Rossides, AFGE ... That a respirator, gloves and hand ...
... the facade, of the disorder, , , TUESDAY, April 28 ... genes can raise the risk for developing autism, according ... genetic roots of the disorder. , Both genes are ... complex social behavior and abstract thought, and are normally ...
... Inc. (NYSE: SFD ) today reiterated its ... or symptoms of the presence of North American influenza ... its joint ventures in Mexico. As previously announced, those ... submitting samples from their swine herds to confirm the ...
... Encryption business continues to drive performance for CompanyDALLAS, April ... ), the leader in hosted services for email encryption ... first quarter ended March 31, 2009. ZixCorp recorded ... net loss of $1.5 million for the quarter, or ...
... the country, have identified a new gene variant that is ... activity of the gene, known as CDH10, in the fetal ... regions that support language, speech and interpreting social behavior. ... edition of the journal Nature , the two findings ...
Cached Medicine News:Health News:OHSU Knight Cancer Institute to study new radiation technology for head, neck cancer 2Health News:AFGE: TSA Must Do More to Protect Its Workforce and the Public 2Health News:Research Highlights Genetic Risk for Autism 2Health News:Research Highlights Genetic Risk for Autism 3Health News:Research Highlights Genetic Risk for Autism 4Health News:Smithfield Foods Says North American Influenza Not Present in Any of Its Worldwide Operations and Pork is Safe to Eat 2Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 2Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 3Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 4Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 5Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 6Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 7Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 8Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 9Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 10Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 11Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 12Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 13Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 14Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 15Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 16Health News:Zix Corporation Reports Highest Revenue Quarter as Company Announces First Quarter 2009 Financial Results 17Health News:World's largest DNA scan for autism uncovers new gene variant for disorder 2Health News:World's largest DNA scan for autism uncovers new gene variant for disorder 3
(Date:8/29/2014)... PITTSBURGH , Aug. 29, 2014 /PRNewswire-iReach/ -- ChemImage ... at the Australian and New Zealand Forensic Science ... Forensic Sciences in Adelaide, Australia ... discussion concerning the advancements that hyperspectral imaging can ... Jeffrey Beckstead , Director of Product Development ...
(Date:8/29/2014)... , Aug. 29, 2014  Pacific Medical Data ... new website design . The main website, along ... showcases the company,s new services and content relevant to ... a new streamlined design, viewers can now better understand ... health care practices and create a more visible platform ...
(Date:8/29/2014)... , August 29, 2014 ... participate in the inaugural Tweetchat taking place in ... Worldwide , organised by UBM Live , ... #CPhIChat is a first of its kind global ... across the supply chain, aimed to stimulate conversations ...
Breaking Medicine Technology:ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3PMDS Announces New Website 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 2CPhI Worldwide to Host #CPhIChat Provoking Debate on the Future of Pharma 3
... Md., July 3 All newborn infants,should be ... at birth,according to a new recommendation from the ... accompanying summary of evidence appear,in the July 7 ... impaired at birth, during infancy or in early,childhood ...
... for Healthcare ... Professionals, VOORHEES, ... that causes disease with a wide spectrum of,severity, ranging from mild ... to 20% of patients who develop an initial,case of CDI.(1) These ...
Cached Medicine Technology:Task Force Recommends Screening for Hearing Loss in All Newborns 2Task Force Recommends Screening for Hearing Loss in All Newborns 3Current Concepts in Clostridium difficile Infection: A Focus on Recurrent Disease 2
... Laparoscopic Instruments incorporate a layered design unique ... and monitored to prevent stray electrosurgical burns ... by insulation failure or capacitive coupling; a ... built into all AEM Instruments provides a ...
... AEM Laparoscopic Instruments incorporate a layered design ... shielded and monitored to prevent stray electrosurgical ... caused by insulation failure or capacitive coupling; ... shield built into all AEM Instruments provides ...
... incorporate a layered design unique in the ... to prevent stray electrosurgical burns along the ... failure or capacitive coupling; a well-documented patient ... all AEM Instruments provides a neutral return ...
... 5mm AEM Laparoscopic Instruments incorporate a layered ... are shielded and monitored to prevent stray ... instrument caused by insulation failure or capacitive ... protective shield built into all AEM Instruments ...
Medicine Products: