Navigation Links
Neurogenesis in the adult brain: The association with stress and depression
Date:8/31/2008

an not only stimulate neurogenesis, but also exert similar stimulatory effects on gliogenesis. Moreover, animal studies have recently shown that chronic stress inhibits cell proliferation not only in the hippocampus but also in the prefrontal cortex, and that this inhibitory effect can be counteracted by antidepressant treatment (Czh et al., 2007). The significance of these observations is strengthened by in vivo neuroimaging studies in patients with mood disorders that consistently point to the involvement of prefrontal brain sites in the pathophysiology of the disease. These imaging findings are further supported by reports on human post-mortem tissues revealing that the number of glial cells in the prefrontal cortex is adversely affected in patients with mood disorders.

Experiments show that stress and depression inhibit the growth of new nerve cells as well as glial support cells, and that this inhibitory effect can be counteracted by antidepressive therapy.

Clinical implications

  • Within the last two decades, the understanding of the mature brain has changed: Neuronal and glial cell networks in the brain are far from being fixed and immutable a multitude of factors such as environmental stimulation, learning, growth factors, glucocorticoids, sexual hormones, stress, aging, and several neurotransmitters regulate the generation of new neurons. Antidepressants stimulate the growth of neurons and glial cells again so the brain changes that occur as a consequence of stress and depression are generally reversible.

  • Today it is widely believed that neurogenesis in the adult brain is restricted to selected brain regions such as zones of the hippocampus and the lateral brain ventricles. However, a growing number of recent studies describe the generation of new neurons also in the adult neocortex. Although small in both number and size, these new cells could have a significant impact on neocortical function.


    '/>"/>

Contact: Sonja Mak
s.mak@update.europe.at
43-140-557-340
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Neurogenesis in the adult brain: The association with stress and depression
2. Younger Adults in Illinois Aided by Expansion of Health Care Coverage
3. 79 million US adults have medical bill problems or are paying off medical debt
4. Older Adults Reluctant to Question Surgical Treatment
5. Study shows that older adult caregivers of people with dementia have worse sleep than noncaregivers
6. Poor Coordination in Childhood Tied to Adult Obesity
7. State Support for Programs to Decrease Tobacco Use Among Teens and Adults on the Decline According to Trend Report Released Today
8. Half of U.S. Adults Lack 20/20 Vision
9. When it comes to abstinence teens, adults arent speaking the same language
10. KLRI Receives Grant From NIH to Study Stress Resilience in Older Adults
11. Risk of unintentional injury death is high for young children living with unrelated adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... is a leading review website in the world. It ... announced that GreenGeeks, Arvixe and Hostgator are the best ... http://www.greengeeks.com/cgi-bin/affiliates/clickthru.cgi?id=seohosts ) is one of the best web hosting ... of useful products for sale. On its website, customers ... , As one of the Top 10 Web Hosting ...
(Date:9/1/2014)... Television shows filled with action and sound may be ... cookies, carrots and grapes while watching an excerpt from ... program. , , Television has been blamed for helping ... lifestyle. But the focus of why has been on ... other distracting activities that can cause people to eat ...
(Date:9/1/2014)... News) -- You may be able to convince your brain ... suggests. The study included eight overweight and obese people ... to change how people react to different foods. These participants ... obese people who weren,t in the program. Both groups ... and again six months later. The scans revealed that the ...
(Date:9/1/2014)... (PRWEB) September 01, 2014 An operating ... a hospital for performing surgical operations. An operating room ... tables, surgical booms, operating room lights, imaging displays as ... a report by Transparency Market Research, a U.S.-based market ... to reach USD 4.5 billion by 2019. , ...
(Date:9/1/2014)... Dennis Thompson HealthDay ... An experimental Ebola drug previously given to two American aid ... deadly virus in laboratory tests, researchers report. The drug, ... even if they didn,t get the medication until five days ... of Ebola who were days or even hours away from ...
Breaking Medicine News(10 mins):Health News:The Best Reseller Hosting Suppliers in August Released by Leading Review SiteTop10BestSEOHosting.com 2Health News:Research letter: Viewers ate more while watching Hollywood action flick on TV 2Health News:Train Your Brain to Choose Fruit Salad Over French Fries 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 2Health News:Operating Room Equipment Market Study 2019 by Transparency Market Research 3Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 2Health News:Monkey Trial Supports Ebola Drug That May Have Helped 2 Stricken Americans 3
... to develop the colorectal polyps that can precede colon cancer. ... patients attending for colonoscopy. They found the incidence of polyps// ... cancer - to be greater among current smokers than in ... likely to have more than two polyps, growths greater than ...
... of the antioxidant vitamin E may assist in reducing ... Health Study and the Health Professionals Follow-Up Study', presented by ... Parkinson's disease. The participants have been followed up for several ... ,Those with a high intake of vitamin E ...
... UK inserting a coil into a weakened blood vessel offers ... rate from subarachnoid haemorrhage// - caused by a bursting of ... to 40 per cent in the first 24 hours after ... a clip to prevent further rupture of the blood vessel. ...
... medical centers hope to arbitrate whether a laser can stop ... two forms of macular degeneration, wet and dry. //The dry ... by the formation of yellowish deposits within the layers of ... have a gradual loss of vision. While there are a ...
... researchers of University of Kansas it is observed that poorly ... pain, gas and diarrhea.// Often people suffer from bowel symptoms ... can be found. They have found out that a high ... to digest fructose. ,Found in honey, fruits and ...
... that endometriosis is linked to infertility. There has long ... shows one of the reasons why the disease may ... patients, but concluded that endometriosis causes a certain action ... fluid located near the fallopian tubes. They then studied ...
Cached Medicine News:
(Date:8/29/2014)... Aug. 29, 2014 Research and Markets ... and Development Trend Forecast of Pharmaceutical Equipment Market in ... Research and Development Trend Forecast of Pharmaceutical Equipment ... analyzes China,s pharmaceutical equipment industry ... demand, competition landscape, and business performance of domestic major ...
(Date:8/29/2014)... 2014 According to the ... Services (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User ... Gene Synthesis, NGS, DNA, RNAi) - Global Forecast ... Synthesis Market is expected to reach $1,712.1 Million ... at a CAGR of 9.8% from 2014 to ...
(Date:8/29/2014)... 2014 /PRNewswire-iReach/ -- ChemImage will present a workshop focused ... Zealand Forensic Science Society,s 22 nd International ... Adelaide, Australia .  Forensic Scientists will be ... hyperspectral imaging can bring to examination procedures. ... of Product Development at ChemImage, will host a ...
Breaking Medicine Technology:Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3
This is the second generation of the famous A/O sliding microtome, manufactured in the United States under the Leica trademark....
... base sliding microtome offers the ultimate in ... not least, safety. ,Designed to meet the ... 8000 will also meet the more demanding ... versatility and wide range of accessories will ...
... MNL 440601 Small Sledge Microtome is ideal for ... or skin specimens. Specimen rise is automatic ... 30 microns in increments of 2 microns. ... Stages.,Other Associated Products, Vibratomes Freezing Stages ...
... is a solid solution for setting ... the Vibratome Plus, standard accessory kit, ... mounts w/1/2" head, and a rotating ... of your sectioning needs.,For selection assistance, ...
Medicine Products: