Navigation Links
Neurogenesis in the adult brain: The association with stress and depression
Date:8/31/2008

luence, as well as negative modulators such as acute and chronic stress.

While stress has been found to inhibit adult neurogenesis in the hippocampus a brain area that is central to emotion, memory and learning , antidepressant treatment has the opposite effect. Moreover, patients with mood disorders often have reduced hippocampal volumes. This evidence rapidly led to the formulation of the 'neurogenesis hypothesis' of depression, which says that adult neurogenesis in the hippocampus is a candidate substrate for both the etiology and the treatment of major depressive disorders. However, according to the current view, newborn cells in the hippocampus per se may not be critical for the development of depression, but may be required for certain behavioural effects of antidepressants (Sahay & Hen, 2007).

Recent research has proven that the adult brain is capable of generating new nerve cells (neurons). Neurogenesis can be influenced by positive and negative modulators.

The role of gliogenesis

There is increasing evidence that in addition to neurogenesis, stress and antidepressant treatment also induce changes in the formation of specific glial support cells (=gliogenesis) that are critical for the survival of the neurons in the brain. There are about 100 times more glial cells than nerve cells, providing energy and nutrition to the neurons. Besides their housekeeping functions, glial cells are instrumental to neural communication and regarded as dynamic regulators of synaptic strength and synapse formation. They also possess receptors for neurotransmitters and steroid hormones that, similarly to receptors of neurons, can trigger electrical and biochemical events in the cell. Therefore, structural changes of glial cells are likely to have an important functional significance for the communication between neurons and between neurons and glial cells.

In the adult brain various antidepressant treatment strategies c
'/>"/>

Contact: Sonja Mak
s.mak@update.europe.at
43-140-557-340
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Neurogenesis in the adult brain: The association with stress and depression
2. Younger Adults in Illinois Aided by Expansion of Health Care Coverage
3. 79 million US adults have medical bill problems or are paying off medical debt
4. Older Adults Reluctant to Question Surgical Treatment
5. Study shows that older adult caregivers of people with dementia have worse sleep than noncaregivers
6. Poor Coordination in Childhood Tied to Adult Obesity
7. State Support for Programs to Decrease Tobacco Use Among Teens and Adults on the Decline According to Trend Report Released Today
8. Half of U.S. Adults Lack 20/20 Vision
9. When it comes to abstinence teens, adults arent speaking the same language
10. KLRI Receives Grant From NIH to Study Stress Resilience in Older Adults
11. Risk of unintentional injury death is high for young children living with unrelated adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... (PRWEB) July 31, 2014 The shale ... to the top of current U.S. natural gas production ... a “boom and bust” cycle, similar to previous resource ... study released today by Washington & Jefferson College’s (W&J) ... Environmental Law Institute (ELI) confirms that the gas boom ...
(Date:7/31/2014)... 31, 2014 Some pain relief medications can ... side effects. Every day, 46 people in the U.S. ... than 30 people are admitted to an emergency room because ... look at the dangers of prescription and over-the-counter painkillers and ... to do more to make these drugs safer. , The ...
(Date:7/31/2014)... Angeles, CA (PRWEB) July 31, 2014 Staying ... can be tricky at best. Men and women get sucked ... husbands, wives, life partners, and taxi services to kids. ... Black, offers her "3 Fast + Fun Ways to Reignite ... free download . , “This is a much better ...
(Date:7/31/2014)... Hills, CA (PRWEB) July 31, 2014 ... at a total cost of $11.8 billion, and this ... the Anacapa Dental Art Institute in Woodland Hills and ... contain the teeth-protecting mineral fluoride. , “Tap water is ... the Anacapa Dental Art Institute. “Adding fluoride to municipal ...
(Date:7/31/2014)... 2014 Perhaps some people are unaware of ... old from the first day when we were born on ... downs during their whole life. Some people may live without ... it is not necessary for people to worry about that. ... Auto, a famous China automobile manufacturer , is one ...
Breaking Medicine News(10 mins):Health News:Pennsylvania’s Shale Gas: Examining the Boom and Bust Cycle 2Health News:Pennsylvania’s Shale Gas: Examining the Boom and Bust Cycle 3Health News:Consumer Reports Warns Against the Risks of Prescription and Over-The-Counter Painkillers 2Health News:Consumer Reports Warns Against the Risks of Prescription and Over-The-Counter Painkillers 3Health News:Couples in Trouble Relationship Expert, Dr. Jackie Black, Offers a Gift Guide to Reignite the Spark So Lovers Can Kiss-And-Make-Up 2Health News:Couples in Trouble Relationship Expert, Dr. Jackie Black, Offers a Gift Guide to Reignite the Spark So Lovers Can Kiss-And-Make-Up 3Health News:Woodland Hills Top Cosmetic Dentists Offer 5 Tips for Getting More Teeth-Protecting Fluoride 2Health News:Woodland Hills Top Cosmetic Dentists Offer 5 Tips for Getting More Teeth-Protecting Fluoride 3Health News:Woodland Hills Top Cosmetic Dentists Offer 5 Tips for Getting More Teeth-Protecting Fluoride 4Health News:Woodland Hills Top Cosmetic Dentists Offer 5 Tips for Getting More Teeth-Protecting Fluoride 5Health News:FodayAuto.com: Do Not Be Afraid of Getting Old 2
... MINNEAPOLIS, Feb. 28 In its ongoing contribution to science and the ... new Eniva (R) ... Reduce r (TM) ... liquid nutritional supplement is Eniva,s newest heart health product, designed to support ...
... recently was honored for excellence in management recruiting by being ... BusinessWeek profile may be viewed at the following link: ... ... (PRWEB) February 28, 2009 -- Doug Smith, chief executive officer ...
... rotator cuff repair surgery experienced pain relief and improved shoulder ... study presented at the 2009 American Orthopaedic Society of Sports ... be caused by a traumatic event to the shoulder, such ... to wear and tear, which is more common in athletic ...
... cabergoline cut consumption, were less prone to relapse , , ... prescribed to help with infertility and menstrual disorders may ... When injected with cabergoline (Dostinex), rats addicted to alcohol ... less prone to relapsing, a study by researchers at ...
... Feb. 27 Grupo Casa Saba ("Saba,","GCS," "the Company" ... of the leading Mexican,distributors of pharmaceutical products, beauty aids, ... products,announces its consolidated financial and operating results for the ... Highlights: , (All December ...
... Rankin Shapiro, PhD, have collaborated for 20 years to ... Barrow Neurological Institute at St. Joseph,s Hospital and Medical ... the Shapiros have established a $1.5 million endowed chair ... represents our desire to give back and will allow ...
Cached Medicine News:Health News:New Innovation for Battling Number One Killer in America Introduced by Eniva Nutraceutics 2Health News:New Innovation for Battling Number One Killer in America Introduced by Eniva Nutraceutics 3Health News:New Innovation for Battling Number One Killer in America Introduced by Eniva Nutraceutics 4Health News:New Innovation for Battling Number One Killer in America Introduced by Eniva Nutraceutics 5Health News:Doug Smith Named One of BusinessWeek's "World's Most Influential Headhunters" 2Health News:Hormone Drug May Help Drinkers Stay Sober 2Health News:Grupo Casa Saba Announces 4Q08 Earnings Results 2Health News:Grupo Casa Saba Announces 4Q08 Earnings Results 3Health News:Grupo Casa Saba Announces 4Q08 Earnings Results 4Health News:Grupo Casa Saba Announces 4Q08 Earnings Results 5Health News:A lifetime of paying it forward 2
(Date:7/30/2014)... , July 30, 2014 /PRNewswire-iReach/ -- Transluminal Technologies ... medical device company, has announced today that they ... CD™ Vascular Closure Device. Velox CD™ provides a ... following percutaneous femoral procedures. The single size velox ... in size from 5F to 8F.  ...
(Date:7/30/2014)... 2014  InnoPharma, Inc. today announced the first generic ... of Zyprexa® injection), in Canada.  Olanzapine is indicated for ... patients with schizophrenia or bipolar I mania. ... has entered into an agreement with Sandoz Canada Inc., ... use, sell, market and distribute Olanzapine Injection in ...
(Date:7/30/2014)... , July 30, 2014  Regeneron Pharmaceuticals, Inc. ... and NYSE: SNY ) today announced that ... people with hypercholesterolemia met their primary efficacy endpoint of ... cholesterol (LDL-C) at 24 weeks compared to placebo or ... PCSK9 (proprotein convertase subtilisin/kexin type 9). In ...
Breaking Medicine Technology:Transluminal Technologies receives CE Mark approval for velox CD(TM) vascular closure device 2InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 3Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 4Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 5Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 6Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 7Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 8
... Masimo (Nasdaq: MASI ), ... Masimo rainbow Acoustic Monitoring™ , and Masimo ... announces an expanded supplier agreement that adds Masimo rainbow ... contract with Premier Purchasing Partners, LP, the group purchasing ...
... Ala., Aug. 19 The Specialty Pharma Association announces its Fall ... be held September 15-17, 2010 at the San Diego Marriott Hotel ... Conference will include the following: Carole DeRoche, President ... Vice President Kantar Health Kurt ...
Cached Medicine Technology:Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 2Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 3Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 4Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 5
... TruFit® CB Plugs use OBIs ... a scaffold for tissue repair that ... stable. A patented composite of ... the PolyGraft® material can be fabricated ...
The TruGraft BGS Granules are to be used in bone void filling of surgically or traumatically created osseous defects....
... the first to manufacture a diode pumped ... to announce their newest addition, the VITRA. ... the problem that many doctors face when ... No larger than a shoe box, this ...
... Resistant Tips offer a safe alternative to ... designed for applications such as PCR(a), pipetting ... ART Tips are excellent for tissue culture, ... ART Tips prevent aerosol contaminants and liquids ...
Medicine Products: