Navigation Links
Nanodiamond-embedded contact lenses may improve glaucoma treatment
Date:2/18/2014

ase of medication into the eye, the UCLA researchers combined nanodiamonds with timolol maleate, which is commonly used in eye drops to manage glaucoma. When applied to the nanodiamond-embedded lenses, timolol is released when it comes into contact with lysozyme, an enzyme that is abundant in tears.

"Delivering timolol through exposure to tears may prevent premature drug release when the contact lenses are in storage and may serve as a smarter route toward drug delivery from a contact lens." said Kangyi Zhang, co-first author of the study and a graduate student in Ho's lab.

One of the drawbacks of traditional timolol maleate drops is that as little as 5 percent of the drug actually reaches the intended site. Another disadvantage is burst release, where a majority of the drug is delivered too quickly, which can cause significant amounts of the drug to "leak" or spill out of the eye and, in the most serious cases, can cause complications such as an irregular heartbeat. Drops also can be uncomfortable to administer, which leads many patients to stop using their medication.

But the contact lenses developed by the UCLA team successfully avoided the burst release effect. The activity of the released timolol was verified by a primary human-cell study.

"In addition to nanodiamonds' promise as triggered drug-delivery agents for eye diseases, they can also make the contact lenses more durable during the course of insertion, use and removal, and more comfortable to wear," said Ho, who is also a professor of bioengineering and a member of the Jonsson Comprehensive Cancer Center and the California NanoSystems Institute.

Even with the nanodiamonds embedded, the lenses still possessed favorable levels of optical clarity. And, although mechanical testing verified that they were stronger than normal lenses, there were no apparent changes to water content, meaning that the contact lenses' comfort and permeability to oxygen wou
'/>"/>

Contact: Brianna Deane
bdeane@dentistry.ucla.edu
310-206-0835
University of California - Los Angeles
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New insights into when beach sand may become unsafe for digging and other contact
2. First contact: Early intervention key in diagnosis and treatment of serious mental illness
3. Phone contact with nurses linked with better outcomes for women with gestational diabetes
4. US Drug Watchdog Launches Now Calls Transvaginal Mesh A Disaster For 100,000's of US Women Recipients And Offers The Names and Contacts Of The Best Women Attorneys
5. The US Drug Watchdog Now Urges Plaintiffs Law Firms Worldwide To Contact Them About A Possible International Effort To Help Victims Of Defective Drugs Or Medical Devices
6. Skin contact breast tumor detection
7. Close contact with young people at risk of suicide has no effect
8. Halloween Warning: Decorative Contact Lenses May Damage Your Eyes
9. Air exposure between blinks affects deposits on contact lenses
10. Dont Take Shortcuts When Caring for Contact Lenses: Expert
11. The US Drug Watchdog Now Urges Women Who Suffered A Heart Attack Or Stroke After Using Yaz Yasmin Birth Control Pills To Contact The Johnson Law Group Immediately
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... FRIDAY, Aug. 29, 2014 (HealthDay News) -- Selling cigarettes ... or illegal tobacco and doesn,t harm sales in small ... problems were predicted by the tobacco industry when it ... in the world to introduce plain packaging for tobacco ... Ireland, New Zealand and the U.K. Researchers surveyed ...
(Date:8/29/2014)... August 29, 2014 Honey Gifts, premium ... company will now be selling purse-sized adult toys and ... way that they can be carried in a woman’s ... the purse-sized range at Honey Gifts is also leak-free ... life and rechargeable batteries are common characteristics of Honey ...
(Date:8/29/2014)... Barbara, CA (PRWEB) August 29, 2014 ... in Santa Barbara in the Santa Barbara News-Press Readers’ ... Evolutions won the Readers’ Choice poll as Best Medical ... 20, 2014 reads the following about Evolutions Medical Spa ... spa, but it is recognized as a top-notch, cutting-edge ...
(Date:8/29/2014)... COLUMBUS, Ohio (PRWEB) August 29, 2014 ... vice president of operations & business development. , Rees ... the vice president of business development. , A wholly ... (OPRS), Senior Independence provides older adults with options, including ... teams, in-home care (e.g., meal preparation) and therapeutic adult ...
(Date:8/29/2014)... Last week, the Fed reported an increase in ... rose to 0.4% while manufacturing output progressed to 1.0%. ... boost since February this year. Capacity use has increased by ... – an increase that could be attributed to the boost ... which is a measure of slack across the industries. , ...
Breaking Medicine News(10 mins):Health News:Study Counters Critics of Plainer Cigarette Packaging 2Health News:Honey Gifts Now Provides Purse Sized Adult Toys in Vancouver 2Health News:Evolutions Named Best Medical Spa in Santa Barbara by Santa Barbara News Press 2Health News:Evolutions Named Best Medical Spa in Santa Barbara by Santa Barbara News Press 3Health News:Senior Independence Promotes Rees to Vice President of Operations & Business Development 2Health News:LeaseQ Announces That Recent Industrial Production Report Spells Good Things For The Equipment Leasing Industry 2Health News:LeaseQ Announces That Recent Industrial Production Report Spells Good Things For The Equipment Leasing Industry 3
... Findings may explain link between breathing in dirty air ... -- Long-term exposure to the air pollution particles caused ... blood pressure, U.S. researchers say. , In the new ... Normative Aging Study, who were assessed every four years ...
... warmer than 75 degrees poses added risks , THURSDAY, March ... deaths in New York City go up with the temperature: ... 75 degrees Fahrenheit. , The findings, published online March ... death statistics in the city from 1990 through 2006. , ...
... ... ... ... ...
... replicate the human brain, or to develop nanotechnology that ... neurons and other types of cellular networks? Once ... other in ways that could propel extraordinary new research. ... an hour-long conversation recently led by neuroscientist Nicholas Spitzer. ...
... , ... ... ... ...
... Henry Ford Hospital study has shown a link between Vitamin ... lead researchers to better understand the development of the most ... researchers at Henry Ford and Wayne State University found elevated ... taken from 10 patients compared to normal skin tissue taken ...
Cached Medicine News:Health News:Years of Exposure to Traffic Pollution Raises Blood Pressure 2Health News:Anthera Pharmaceuticals Completes Initial Public Offering 2Health News:Anthera Pharmaceuticals Completes Initial Public Offering 3Health News:Anthera Pharmaceuticals Completes Initial Public Offering 4Health News:Anthera Pharmaceuticals Completes Initial Public Offering 5Health News:Anthera Pharmaceuticals Completes Initial Public Offering 6Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 2Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 3Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 4Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 5Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 6Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 7Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 8Health News:Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss 9
(Date:8/29/2014)...   Vittamed Corporation , a neurodiagnostics medical device company ... T. (Teo) Forcht Dagi , MD, DmedSc, MPH, MBA, ... " Teo Forcht Dagi is an ... and venture capital," said Remis Bistras , President and ... clinical, strategic, and entrepreneurial expertise to our Board." ...
(Date:8/29/2014)... 2014 /PRNewswire-iReach/ -- ChemImage will present a workshop focused ... Zealand Forensic Science Society,s 22 nd International ... Adelaide, Australia .  Forensic Scientists will be ... hyperspectral imaging can bring to examination procedures. ... of Product Development at ChemImage, will host a ...
(Date:8/29/2014)... 2014  Pacific Medical Data Solutions is excited to ... . The main website, along with the site,s blog, ... services and content relevant to the medical billing industry. ... viewers can now better understand how PMDS products help ... create a more visible platform about medical billing best ...
Breaking Medicine Technology:Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 2ChemImage to Discuss Hyperspectral Imaging for Forensic Investigation at the ANZFSS 22nd International Symposium on the Forensic Sciences 3PMDS Announces New Website 2
... Skin Infections, SAN DIEGO, Sept. 22 Trius ... of the oral form of its,second-generation oxazolidinone antibacterial drug ... tolerability of once-daily doses,of 200, 300 and 400 milligrams ... for five to seven days of treatment., The ...
... whose breast cancer has,spread to their lymph nodes, a ... the method for determining whether those,women need radiation therapy ... presented during the annual meeting of the American Society ... Boston., In a retrospective study of 167 patients ...
Cached Medicine Technology:Trius Doses First Patient in Antibacterial Phase 2 Trial 2Breast MRI Scan Could Determine Need for Radiation Therapy 2
... Suture™ ENDO PADDLE RETRACT™ 12 mm instrument ... general, urologic,thoracic, colorectal and other endoscopic procedures ... stomach, or liver. , ,The ENDO ... retractor at the distal end of the ...
... Introducing the widest offering of single-use instruments ... and long 43cm lengths for Bariatric Surgery. ... , Extended insulation covers the pivot points to ... , A 4mm universal cord, which eliminates gapping ...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Medicine Products: