Navigation Links
NEJM study points to new era in hepatitis C treatment
Date:6/5/2009

Drs. Gregory Everson of the University of Colorado Health Science Center; Stuart Gordon of Henry Ford Hospital; Mark Sulkowski of Johns Hopkins School of Medicine; and Robert Kauffman, Lindsay McNair and John Alam of Vertex Pharmaceuticals.

Drs. Jacobson, McHutchison and Muir have received consulting fees and/or grant support from Vertex, Roche (maker of peginterferon) and Schering-Plough (maker of ribavirin).

The study's results match those of a similar study conducted in Europe that was reported on in the same issue of the New England Journal of Medicine. An accompanying editorial recounts the history of hepatitis C treatments, beginning 25 years ago with the discovery of interferon. It comments on the two studies: "Telaprevir appears to be a material advance in the therapy of hepatitis C, beginning a new era of treatment -- an era of antiviral agents developed specifically to target this virus."

Two Phase III studies currently under way at NewYork-Presbyterian/Weill Cornell and centers worldwide will attempt to confirm the results, potentially leading to FDA approval of telaprevir. One study is looking at 12 weeks of telaprevir in combination with standard therapy (peginterferon alfa-2a and ribavirin) followed by either 12 or 36 weeks of standard therapy alone depending on patients' response to therapy. A second study is comparing 8-week and 12-week regimens of telaprevir in combination with standard therapies followed by at least 12 weeks of standard therapy, depending on patients' response to therapy, to a placebo group taking 48 weeks of standard therapy alone. Both studies are currently closed to recruitment.


'/>"/>

Contact: Linda Kamateh
lib9027@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Penn study finds pro-death proteins required to regulate healthy immune function
2. New study shows promise in reducing surgical risks associated with surgical bleeding
3. Study, meta-analysis examine factors associated with death from heatstroke
4. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
5. Study says COPD testing is not measuring up
6. Preclinical study suggests organ-transplant drug may aid in lupus fight
7. Ability to cope with stress can increase good cholesterol in older white men, study finds
8. High alcohol consumption increases stroke risk, Tulane study says
9. Mailman School of Public Health study examines link between racial discrimination and substance use
10. Pitt study finds inequality in tobacco advertising
11. Stanford study highlights cost-effective method of lowering heart disease risks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... a review published in the April issue of ... Feinstein Institute for Medical Research, says it,s time to ... approach to treating sepsis, which kills millions worldwide ... occurs when molecules released into the bloodstream to fight ... Inflammation is necessary for maintaining good health without ...
(Date:4/17/2014)... team has created a new technology for modifying ... travel the body and selectively target cancer and ... devices that monitor and modify human physiology is ... no existing technology enabled bioengineers to build such ... respond in a customized fashion. , "The project ...
(Date:4/17/2014)... Doctors who treat patients with a severe ... face an agonizing treatment decision. , The drug ... help relieve shortness of breath. But some patients ... cause potentially fatal complications following transplantation. , "It,s ... medical director of Loyola University Medical Center,s LAM ...
(Date:4/17/2014)... 2014) The cause of neuronal death in Parkinson,s ... that neurons may be mistaken for foreign invaders and ... the way autoimmune diseases like type I diabetes, celiac ... study was published April 16, 2014, in Nature ... controversial, idea in Parkinson,s disease; but if true, it ...
(Date:4/17/2014)... 17, 2014 By discovering a new mechanism that ... stroke, researchers at UC Irvine and the Salk Institute ... limit or prevent stroke-induced brain damage. , A complex ... of death and primary reason for disability in the ... stroke and lets blood-borne material into the brain, causing ...
Breaking Medicine News(10 mins):Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Building 'smart' cell-based therapies 2Health News:Patients with rare lung disease face agonizing treatment dilemma 2Health News:Patients with rare lung disease face agonizing treatment dilemma 3Health News:Is Parkinson's an autoimmune disease? 2Health News:Study IDs new cause of brain bleeding immediately after stroke 2
... Reporter , TUESDAY, Feb. 22 (HealthDay News) -- Nitroglycerin ... counter bone loss, a new study suggests. As ... is increasing. Nitroglycerin appears to increase bone density ... over newer and more costly drugs, the researchers noted. ...
... new type of nanoparticle that could safely and effectively deliver ... The new particles, described in the Feb. 20 issue of ... can carry synthetic versions of proteins normally produced by viruses. ... to that produced by live virus vaccines but should ...
... (Feb. 22, 2011) Three American College of Radiology ... the ACR Board of Chancellors will outline strategies for ... minimize medical radiation exposure at a Feb. 24, 25 ... "NIH Summit to Focus on Management of Radiation Dose ...
... NY) In an advance that could improve battlefield ... of Medicine of Yeshiva University have used tiny ... loss. Nanoparticles containing nitric oxide (NO) were infused into ... circulation and protect vital organs. The research was reported ...
... TUESDAY, Feb. 22 (HealthDay News) -- The increasingly commonplace ... labor for convenience rather than for medical necessity entails ... suggests. The new report, which highlights the negative ... first-time mothers, indicates that going that route increases the ...
... respond differently to their crying babies than do non-depressed ... at the University of Oregon, is much more muted ... An infant crying is normal, but how mothers respond ... professor of psychology. For years, Ablow has studied the ...
Cached Medicine News:Health News:Nitroglycerin Ointment Might Strengthen Bones 2Health News:Nitroglycerin Ointment Might Strengthen Bones 3Health News:MIT engineers design new nanoparticle that could lead to vaccines for HIV, malaria, other diseases 2Health News:MIT engineers design new nanoparticle that could lead to vaccines for HIV, malaria, other diseases 3Health News:ACR commission and committee chairs and former board chair to present at NIH Radiation Dose Summit 2Health News:Nanoparticles increase survival after blood loss 2Health News:Induced Labor Linked to Raised Risks for First-Time Moms 2Health News:Crying baby draws blunted response in depressed mom's brain 2Health News:Crying baby draws blunted response in depressed mom's brain 3
(Date:1/14/2014)... Texas , Jan. 14, 2014  Luminex Corporation (Nasdaq: ... results for the fourth quarter of 2013 on Monday, February ... for release after the close of trading. ... conference call to discuss the operating highlights and financial results ...
(Date:1/14/2014)... Dynamic Healthcare Services, Inc. ("DHS"), a portfolio company of GMH ... Medical Equipment, Inc. ("Progressive") of Clarion, PA ... were not disclosed. Progressive is a full ... of sleep, mobility, and respiratory products to customers in the ...
(Date:1/14/2014)... 14, 2014   NuAire , a manufacturer of ergonomically designed ... Hitachi Koki of Japan to sell ... America . NuAire will utilize its network of sales professionals ... Canada to offer assistance in application use, product benefits ...
Breaking Medicine Technology:Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2
... Soligenix, Inc. (Soligenix or the Company) (OTC ... biopharmaceutical company, announced today promising preliminary results from ... or BDP) in a canine gastrointestinal acute radiation ... with SGX202 demonstrated statistically significant (p=0.04) improvement in ...
... BOTHELL, Wash., Jan. 18, 2011 BioLife Solutions, ... announced today that it has significantly increased its ... regenerative medicine industry.  The worldwide regenerative medicine market ... hospitals, which are developing cell and tissue-based products ...
Cached Medicine Technology:Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury 2Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury 3Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury 4Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury 5BioLife Solutions Increases 2011 Financial, Scientific, Technical Support of the Regenerative Medicine Industry 2BioLife Solutions Increases 2011 Financial, Scientific, Technical Support of the Regenerative Medicine Industry 3BioLife Solutions Increases 2011 Financial, Scientific, Technical Support of the Regenerative Medicine Industry 4BioLife Solutions Increases 2011 Financial, Scientific, Technical Support of the Regenerative Medicine Industry 5
... The programmer for the ITREL 3 ... programmer and the Model 7457 MemoryMod ... indicated for the treatment of chronic nausea ... drug therapies are not providing adequate relief ...
... Rapid diagnosis of influenza A ... important due to the availability ... diagnosis of influenza using Clearview ... can lead to reduced hospital ...
... ability of the visual system to ... are,some pathological conditions that reduce contrast ... test will help in the identification ... and reduced visual acuity often occur ...
...
Medicine Products: