Navigation Links
Mussel-inspired 'glue' for surgical repair and cancer drug delivery
Date:2/16/2013

hydroxyphenylalanine).

All of Messersmith's biomedical materials contain a synthetic form of DOPA. (He first developed a simple synthetic polymer containing DOPA in 2002.) In his AAAS talk, Messersmith will detail these three medical applications of his materials:

  • Fetal membrane repair. Premature rupture of fetal membranes can occur spontaneously or in association with a surgical procedure. The membranes have limited ability to heal from these ruptures, and the situation often leads to early labor, premature birth and other serious complications. Messersmith's synthetic polymer is formulated as a rapidly solidifying liquid glue that adheres to the wet tissue and seals fetal membrane defects. His group is collaborating with researchers in Europe to conduct in-vivo testing of their mussel-inspired medical sealants for fetal membrane repair.

  • Self-setting antibacterial hydrogels. Silver ions possess antibacterial activity at low concentrations, and this has led to interest in incorporating silver into medical devices. Messersmith employs silver both to induce hydrogel cross-linking via catechol oxidation and as a precursor for silver nanoparticle formation. The silver nanoparticles then become embedded within the hydrogel structure, releasing silver ions to produce an antibacterial effect.

  • Cancer drug delivery and destruction removal of cancer cells. One of Messersmith's polymer designs forms pH-sensitive drug delivery vehicles that are stable and inactive in the bloodstream but are activated in the acidic tumor environment, which liberates the drug. A second design involves modifying the surface of gold nanorods with a mussel-inspired polymer coating, which helps the nanorods target cancer cells. Once at the target, the nanorods are irradiated with near-infrared light to produce highly localized heating that thermally destroys cancer cells.


'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. In children born with severe heart defect, surgical management has little effect on neuro outcomes
2. Nonsurgical Method to Measure Brain Pressure Shows Promise
3. Study examines medicare use for Mohs micrographic surgery and surgical excision for skin cancer
4. New surgical technique for removing inoperable tumors of the abdomen
5. Surgical excision unnecessary in some patients with benign papillomas
6. Boston researcher, surgical oncologist receives national award
7. Surgical removal of abdominal fat reduces skin cancer in mice
8. Surgical Residents Often Fatigued, Study Confirms
9. Study finds Massachusetts health reform leads to increased inpatient surgical procedures
10. Surgical sling reduces risk of weakened bladder control after prolapse surgery, U-M study says
11. DRE Medical Equipment Unveils FX-300+ Surgical Headlight and Light Source
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... LunaDress, with its top dressmaking technologies, has ... the business is showing its latest designs of wedding dresses ... to the company’s CEO, all the fresh new products are ... discounts, up to 80% off. All the clothes from LunaDress ...
(Date:1/22/2015)... Padre Murphy's and Owner Tom Boyle in Glendale, AZ has ... (PPHA). The PPHA's passion for others' well-being and shared ... treated for obstructive sleep apnea (OSA) has propelled them into ... the valley. The most recent plans for an event will ...
(Date:1/22/2015)... 2015 Blue Cross and Blue Shield of ... what it means to “Live Fearless.” , The ... share their stories about how they or someone they know ... by living in the moment. By telling these types of ...
(Date:1/22/2015)... Dallas, TX (PRWEB) January 22, 2015 ... the issue of experience and person-centeredness in the long-term ... moving towards action across the continuum. The paper, “The ... the Continuum,” engages perspectives and practices of the patient, ...
(Date:1/22/2015)... 22, 2015 Carinsurancesavings.biz has released a new ... and dismemberment insurance . , Purchasing an accidental death ... very advantageous. This type of rider provides benefits if the ... be considered a lesser form of life insurance. , ...
Breaking Medicine News(10 mins):Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2
... researchers at the Stanford University School of Medicine and ... with post-traumatic stress disorder and high levels of the ... in the size of the hippocampus - a brain ... ,Although similar effects have been seen in animal studies, ...
... for health professionals must include teaching health professionals how ... experts say. ,Sexuality after cancer is a ... doctor or member of their treating team, say Dr ... Annette Street of La Trobe University’s Clinical School of ...
... new technique safely and effectively removes blood clots in ... and disability. ,The interventional radiology treatment ... patients’ quality of life, relieving symptoms such as pain ... to be active. The “rapid lysis” technique combines a ...
... 3-year-old watches television, the more he or she consumes sugary ... ,“For every one-hour increase in TV viewing per day, ... extra serving per week) and total calories (46.3 more kcal/day)," ... a student at the Harvard Medical School. ...
... human lungs hold secrets to developing new antibiotics, and ... to unlocking those secrets. ,That's the ... will discuss his group's progress toward that goal March ... in Baltimore, Md. ,Ramamoorthy's research group is ...
... national waiting list for kidney transplants have only a ... how long they are on the list. Due to ... developed antibodies that make it very difficult to match ... University have developed a decision process, based on innovative ...
Cached Medicine News:Health News:Severe PTSD Damages Children's Brains: Study 2Health News:Severe PTSD Damages Children's Brains: Study 3Health News:Sex After Cancer 2Health News:DVT Treatment Vacuums Away Blood Clots – Prevents Disabilit 2Health News:Excessive TV Viewing Linked to Poor Eating Habits in Children 2Health News:Excessive TV Viewing Linked to Poor Eating Habits in Children 3Health News:Natural Antibiotics Yield Secrets to Atom-level Imaging Technique 2Health News:Natural Antibiotics Yield Secrets to Atom-level Imaging Technique 3Health News:Research Improves Kidney Transplant Chances for Sensitized Patients 2Health News:Research Improves Kidney Transplant Chances for Sensitized Patients 3
(Date:1/23/2015)... BOSTON , January 23, 2015 Heptares ... is delighted to announce that the Malcolm Campbell ... Congreve (Vice President of Chemistry), Fiona Marshall ... (Chief Executive Officer and co-founder) for the seminal contributions to ...
(Date:1/22/2015)... 22, 2015  ViewRay™, a privately held medical device company, ... distributor agreement with ITOCHU Corporation (Tokyo Stock Exchange TYO: ... the treatment of cancer in Japan ... world,s first and only MRI-guided radiation therapy system that ...
(Date:1/22/2015)... UPI ), a medical device company that develops, ... dysfunctions, today reported financial results for the fiscal 2015 ... for the Company,s Urgent ®  PC Neuromodulation System grew ... as compared to $3.9 million in the third quarter ...
Breaking Medicine Technology:Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 3Uroplasty Reports Record Revenue in Fiscal Third Quarter 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 5Uroplasty Reports Record Revenue in Fiscal Third Quarter 6Uroplasty Reports Record Revenue in Fiscal Third Quarter 7Uroplasty Reports Record Revenue in Fiscal Third Quarter 8Uroplasty Reports Record Revenue in Fiscal Third Quarter 9Uroplasty Reports Record Revenue in Fiscal Third Quarter 10Uroplasty Reports Record Revenue in Fiscal Third Quarter 11Uroplasty Reports Record Revenue in Fiscal Third Quarter 12Uroplasty Reports Record Revenue in Fiscal Third Quarter 13Uroplasty Reports Record Revenue in Fiscal Third Quarter 14Uroplasty Reports Record Revenue in Fiscal Third Quarter 15Uroplasty Reports Record Revenue in Fiscal Third Quarter 16Uroplasty Reports Record Revenue in Fiscal Third Quarter 17Uroplasty Reports Record Revenue in Fiscal Third Quarter 18
... 3 Cornerstone Therapeutics Inc. (Nasdaq: ... specialty pharmaceutical company focused on acquiring, developing and commercializing ... today announced that the Company has licensed to Targacept, ... patents and library of preclinical compounds that target the ...
... , SHANGHAI , ... Shanghai based,life science research service company, and Bio ... research service company, announced today the completion of,a ... The company is using the,funding to scale research & ...
Cached Medicine Technology:Cornerstone Therapeutics Licenses Alpha-7 Technology to Targacept 2Cornerstone Therapeutics Licenses Alpha-7 Technology to Targacept 3Cornerstone Therapeutics Licenses Alpha-7 Technology to Targacept 4Sangon & Bio Basic Inc. Closes $10 Million Round of Investment by Qiming Ventures 2Sangon & Bio Basic Inc. Closes $10 Million Round of Investment by Qiming Ventures 3
... Plasma Reagin card test ... and quantitative determination of ... plasma. Uses carbon particle ... reagin. Kits include 10-well ...
Color-enhanced slide agglutination test for the rapid qualitative and semi-quantitative detection of antistreptolysin O....
Latex agglutination slide test for the qualitative detection of Rotavirus from fecal specimens....
A Color-Enhanced Slide Agglutination Test for the Rapid Qualitative and Semi-Quantitative Detection of Rheumatoid Factor in Serum....
Medicine Products: