Navigation Links
Mussel-inspired 'glue' for surgical repair and cancer drug delivery
Date:2/16/2013

hydroxyphenylalanine).

All of Messersmith's biomedical materials contain a synthetic form of DOPA. (He first developed a simple synthetic polymer containing DOPA in 2002.) In his AAAS talk, Messersmith will detail these three medical applications of his materials:

  • Fetal membrane repair. Premature rupture of fetal membranes can occur spontaneously or in association with a surgical procedure. The membranes have limited ability to heal from these ruptures, and the situation often leads to early labor, premature birth and other serious complications. Messersmith's synthetic polymer is formulated as a rapidly solidifying liquid glue that adheres to the wet tissue and seals fetal membrane defects. His group is collaborating with researchers in Europe to conduct in-vivo testing of their mussel-inspired medical sealants for fetal membrane repair.

  • Self-setting antibacterial hydrogels. Silver ions possess antibacterial activity at low concentrations, and this has led to interest in incorporating silver into medical devices. Messersmith employs silver both to induce hydrogel cross-linking via catechol oxidation and as a precursor for silver nanoparticle formation. The silver nanoparticles then become embedded within the hydrogel structure, releasing silver ions to produce an antibacterial effect.

  • Cancer drug delivery and destruction removal of cancer cells. One of Messersmith's polymer designs forms pH-sensitive drug delivery vehicles that are stable and inactive in the bloodstream but are activated in the acidic tumor environment, which liberates the drug. A second design involves modifying the surface of gold nanorods with a mussel-inspired polymer coating, which helps the nanorods target cancer cells. Once at the target, the nanorods are irradiated with near-infrared light to produce highly localized heating that thermally destroys cancer cells.


'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. In children born with severe heart defect, surgical management has little effect on neuro outcomes
2. Nonsurgical Method to Measure Brain Pressure Shows Promise
3. Study examines medicare use for Mohs micrographic surgery and surgical excision for skin cancer
4. New surgical technique for removing inoperable tumors of the abdomen
5. Surgical excision unnecessary in some patients with benign papillomas
6. Boston researcher, surgical oncologist receives national award
7. Surgical removal of abdominal fat reduces skin cancer in mice
8. Surgical Residents Often Fatigued, Study Confirms
9. Study finds Massachusetts health reform leads to increased inpatient surgical procedures
10. Surgical sling reduces risk of weakened bladder control after prolapse surgery, U-M study says
11. DRE Medical Equipment Unveils FX-300+ Surgical Headlight and Light Source
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... iFitDress.com, a well-known wedding dress manufacturer and retailer, ... cocktail dresses . Included in the new range are ... of these charming outfits are offered at deeply discounted ... promised that all of the sweet 16 cocktail gowns ... mentioning that all of them are set according to ...
(Date:11/26/2014)... HealthDay Reporter WEDNESDAY, Nov. ... be more likely to achieve remission if they maintain a ... found that those who were heaviest had almost 65 percent ... odds of remission. "Medication for rheumatoid arthritis is not ... the study,s lead author and a rheumatologist at the Hospital ...
(Date:11/26/2014)... Steven Reinberg HealthDay Reporter ... adults are smoking cigarettes than ever, health officials said. ... about 21 percent in 2005 to 18 percent in 2013. ... million to 42.1 million, despite the increasing population, according to ... However,"we still have a long way to go, and ...
(Date:11/26/2014)... NJ (PRWEB) November 26, 2014 ... Lourdes Cardiology have launched a partnership designed to ... rates for congestive heart failure (CHF) patients in ... Center staff and Lourdes Cardiology team will help ... and supervised protocols. This partnership pairs the Cardiac ...
(Date:11/26/2014)... Gone are the days when throngs of ... Friday, which signifies the beginning of the Christmas shopping season. ... carts in the comfort of their homes or on the ... is going to be an occasion with one of the ... $2.48 billion in revenue for online retailers according to Adobe ...
Breaking Medicine News(10 mins):Health News:iFitDress.com: Trendy Sweet 16 Cocktail Dresses Unveiled 2Health News:Weight Could Influence Rheumatoid Arthritis Relief 2Health News:Weight Could Influence Rheumatoid Arthritis Relief 3Health News:U.S. Adult Smoking Rate Drops to New Low: CDC 2Health News:U.S. Adult Smoking Rate Drops to New Low: CDC 3Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 2Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 3Health News:2014 Best Friday Deals Revealed by Top10InAction 2
... from Ongoing Glioblastoma Dosimetry Trial Accepted for Oral ... Meeting ----Over 65 Recurrent GBM Patients in Phase ... Cotara to Date, with a Good Safety Profile ... May 28 Peregrine Pharmaceuticals, Inc. (Nasdaq: ...
... 28 iUniverse , the leading provider ... authors around the globe, is hosting Canadian storytellers Elisabeth Richards ... at a pair of free book signings Saturday, May 30 ... take place in the BEA Autographing Area, located on the ...
... Call Your Representatives, Says LTC Expert Denise GottKIRKLAND, Wash., ... affordable, accessible, high-quality health care for all Americans, "There,s ... care gap," says Denise Gott. "Only about 9 million ... long term care insurance. And among those at greatest ...
... House expected to pass companion resolution recognizing sacrifices made ... lives serving their country during the Cold War DENVER, ... a resolution designating October 30, 2009, a national ... workers who served their country during the Cold War ...
... companies looking to benefit from the lucrative coaching market , ... Cincinnati ... the employee wellness market. Companies interested in exploiting this market opportunity ... the goal of controlling skyrocketing health insurance costs, a third of organizations ...
... the Space Shuttle delivered high-resolution video , ... Van ... market leader in high-quality lenses for industrial applications, has just announced ... NASA to play an important role in the recent servicing in ...
Cached Medicine News:Health News:Peregrine Pharmaceuticals Reports Progress in Cotara(R) Brain Cancer Clinical Program 2Health News:Peregrine Pharmaceuticals Reports Progress in Cotara(R) Brain Cancer Clinical Program 3Health News:Peregrine Pharmaceuticals Reports Progress in Cotara(R) Brain Cancer Clinical Program 4Health News:Peregrine Pharmaceuticals Reports Progress in Cotara(R) Brain Cancer Clinical Program 5Health News:Peregrine Pharmaceuticals Reports Progress in Cotara(R) Brain Cancer Clinical Program 6Health News:iUniverse Hosts Canadian Storytellers, Cystic Fibrosis Awareness Advocate for BookExpo America 2009 Book Signings 2Health News:Voters Urged to Support Budding Moves to Include Long Term Care in National Health Reform 2Health News:Voters Urged to Support Budding Moves to Include Long Term Care in National Health Reform 3Health News:Senate Honors Nuclear and Uranium Workers With National Day of Remembrance 2Health News:Hummingbird Coaching's New White Paper on Health Coaching: Build it or Buy it? 2Health News:Hummingbird Coaching's New White Paper on Health Coaching: Build it or Buy it? 3Health News:Hubble Space Telescope Servicing In Orbit Monitored By Three Schneider Lenses 2Health News:Hubble Space Telescope Servicing In Orbit Monitored By Three Schneider Lenses 3
(Date:11/26/2014)... SAN DIEGO , Nov. 26, 2014  Aethlon ... into a definitive agreement to raise approximately $3.3 million ... is being made by one institutional healthcare focused investor. Each ... one-fifth of a common share purchase warrant. Each whole ... at a price of $0.30 for a period of ...
(Date:11/26/2014)... Nov. 26, 2014 Lexicon Pharmaceuticals, Inc. ... completion of previously announced concurrent financing transactions resulting ... and estimated offering expenses, Lexicon anticipates net proceeds ... transactions consisted of: , a public ... to a registration statement that has been declared ...
(Date:11/26/2014)... 26, 2014 Investor-Edge has initiated coverage ... ), Horizon Pharma PLC (NASDAQ: HZNP ), Endocyte ... JNJ ), and Theravance Inc. (NASDAQ: ... accessed at: http://investor-edge.com/register . On Tuesday, November ... the Dow Jones Industrial Average edged 0.02% lower, to finish ...
Breaking Medicine Technology:Aethlon Medical Announces $3.3 Million Equity Investment 2Aethlon Medical Announces $3.3 Million Equity Investment 3Lexicon Announces Completion Of $280 Million In Financing Transactions 2Lexicon Announces Completion Of $280 Million In Financing Transactions 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 2Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 4Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 5
The Universal Knee Positioner(s)™ reduces surgeon fatigue while assisting in the stabilization of a patient's leg during surgury....
... Like other blood salvage devices, the Haemonetics ... cells lost during and after surgery, but ... kind designed specifically to adapt to the ... patients. The system consists of single-patient use ...
... The MicroAire® Hi Speed Pulse Lavage ... bone surfaces as well as cleansing ... Now a great system just got ... effective with the addition of ...
... a complete system of surgical instruments and ... fusion surgery. The system was designed in ... research and engineering with advanced materials, techniques ... different, and because the anatomy of the ...
Medicine Products: