Navigation Links
Melanoma-initiating cell identified by Stanford scientists
Date:6/30/2010

research indicates that it may be more appropriate to also target cells expressing CD271." Such a combination therapy might work to kill both types of cells in the tumor and, hopefully, prevent disease recurrence.

So why do some melanoma tumors seem to have such a large proportion of cancer-initiating cells? Boiko and his colleagues speculate that the answer might lie in the rapidly evolving, aggressive nature of the disease. It's possible that a kind of natural selection among the dividing cancer cells occurs which, in extreme cases selects for one clone, or cell lineage, that for the most part fails to differentiate into non-tumor-initiating cells.

"Extreme care should be taken to identify the origin and the past laboratory history of the cells under study," said Boiko. "Our work was done on primary and minimally passaged patient samples. The variations that we saw in terms of CD271 prevalence in these samples could depend on the stage of the disease the patient was in, and the aggressiveness of that individual cancer."

In addition to Boiko, Weissman, Longaker and Yang, other Stanford researchers involved in the work include post-doctoral fellows Olga Razorenova, PhD, and Daphne Ly, MD; professor of pathology Matt van de Rijn, MD; professor of dermatology Susan Swetter, PhD; associate professor of surgery Denise Johnson, MD; Paris Butler, MD; otolaryngologist Benzion Joshua, MD; and professor of otolaryngology and neurosurgery Michael Kaplan, MD.


'/>"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Mechanism that may trigger degenerative disease identified
2. New Alzheimers Risk Genes Identified
3. Strange Artifact Identified as Ancient Anti-Snoring Device
4. New Alzheimers Gene Identified
5. Newly identified proteins critical to FA pathway DNA repair function
6. Gene Mutations Identified for Charcot-Marie-Tooth Syndrome
7. Salmonella Tennessee Identified in a Processed Food Ingredient
8. Predisposing factors for conversion of mild cognitive impairment to AD identified
9. Meat Might Be Behind Many Unidentified Allergic Reactions
10. Damaged protein identified as early diagnostic biomarker for Alzheimers disease in healthy adults
11. Tumor mechanism identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... 24, 2014 A new report ... 80 percent of doctors in the U.S. have upgraded to ... , Doctors appear to be embracing more digital options. Online ... linking them to past patient histories, the latest published studies, ... , A report from the Robert Wood Johnson Foundation ...
(Date:7/24/2014)... The Arm Lift, also known as brachioplasty, ... skin from the upper arms to create a more toned, ... arm can become lax and may begin to sag, resulting ... the appearance of sagging upper arms, and seek treatment to ... is now offering brachioplasty to tighten and improve the ...
(Date:7/24/2014)... The Republic of Tea, leading purveyor of premium teas, ... to celebrate “The Hundred-Foot Journey,” a new major motion picture ... hundred-foot journey begins in the moment when you bravely drop ... that is far out of your comfort zone. It is ... changes the course of your life for the better. ...
(Date:7/24/2014)... San Jose, California (PRWEB) July 24, 2014 ... market for sugar alcohols, commonly known as food polyols, ... confectionery sectors. Rising incidence of obesity, growing ... rapidly aging population vulnerable to diabetes are some of ... market. With growing number of scientific studies validating the ...
(Date:7/24/2014)... 24, 2014 Freeslate, Inc ... solutions for biopharmaceutical development, today announced its feature ... Formulations” by Jim Kling. Topics of this ... formulations and how automation can help address many ... formulations have been a growing focus of pharmaceutical ...
Breaking Medicine News(10 mins):Health News:Doctors Embracing Changing Technologies, And Technology Brings Options to Treatment 2Health News:Doctors Embracing Changing Technologies, And Technology Brings Options to Treatment 3Health News:How to Get Toned Arms With Arm Lift Procedure 2Health News:How to Get Toned Arms With Arm Lift Procedure 3Health News:The Republic of Tea Unveils New Tea Inspired by “The Hundred-Foot Journey” 2Health News:The Republic of Tea Unveils New Tea Inspired by “The Hundred-Foot Journey” 3Health News:Rising Incidence of Diabetes and Obesity Drives the Global Sugar Alcohols Market, According to New Report by Global Industry Analysts, Inc. 2Health News:Rising Incidence of Diabetes and Obesity Drives the Global Sugar Alcohols Market, According to New Report by Global Industry Analysts, Inc. 3Health News:Freeslate Featured in BioProcess International Article Discussing Challenges and Solutions to Highly Concentrated Protein Formulations 2Health News:Freeslate Featured in BioProcess International Article Discussing Challenges and Solutions to Highly Concentrated Protein Formulations 3
... immediately spot the victims of a bite from the Brazilian ... and an increase in blood pressure, they also sport an ... quest for more Viagras. Scientists say they have figured out ... boost. , “The erection is a side effect ...
... the cancer cells ensure that new blood vessels feed it ... that this can be blocked by a drug commonly used ... Research at Johns Hopkins have discovered that in mice itraconazole ... "We were surprised, to say the least, that itraconazole popped ...
... millions of hours of work productivity this spring//. ,A ... including sneezing, watery eyes and runny and itchy noses, found ... peak hay fever season. ,While missing an hour ... to 50 million Americans suffer from at least some symptoms ...
... can result in serious injury and affect people of all ... yet receives little// , if any, instruction on ladder use ... the May issue of the American Journal of Preventive Medicine ... (CIRP) at Columbus Children’s Hospital, more than 2.1 million individuals ...
... survey reveals that more than one in three HIV positive gay ... in the journal Sexually// Transmitted Infections . Yet, that’s ... that they do the same. ,The findings based on ... London, Manchester, and Brighton between 2003 and 2004, involved information on ...
... dietary changes could be helpful to improve sexual dysfunction ... dysfunction (FSD) includes a variety of disorders that are ... problems with orgasm or pain during sexual activity. ... most loving relationships. It is also an extremely complex ...
Cached Medicine News:Health News:Brazil Spider Offers Hope for Those Suffering from Erectile Dysfunction 2Health News:Hay Fever Can Send Work Productivity Down the Drain 2Health News:Hay Fever Can Send Work Productivity Down the Drain 3Health News:Ladder-related Injuries on the Rise in U.S 2Health News:Condom Promotion-Crucial To HIV/AIDS Prevention 2Health News:Condom Promotion-Crucial To HIV/AIDS Prevention 3Health News:Simple Changes in Diet Could Improve Sex Life of Women 2
(Date:7/23/2014)... Pharmavite LLC announced that Timothy "Tim" Toll ... immediately. Toll recently served as Pharmavite,s executive vice president ... private label and sales administration in the ... Toll will expand his responsibilities to include international sales, ... appointment to chief customer officer is part of a ...
(Date:7/23/2014)... July 23, 2014  RT Oncology Services Corporation today ... join its board of directors. Mr. Mundie is currently ... he works on strategic projects within the company and ... chief research and strategy officer. ... RainTree, said, "Craig is a visionary technology executive. His ...
(Date:7/23/2014)... -- Top Staten Island Pediatrician Dr. Michael ... which discusses tips for parents about pool safety for children. ... According to US News article, "Drowning is the ... aged 1 to 4, and can occur in as little ... the article says that watching a child in the water ...
Breaking Medicine Technology:Craig Mundie Joins RainTree Oncology Board of Directors 2Craig Mundie Joins RainTree Oncology Board of Directors 3Premier Staten Island Pediatrician Dr. Michael Gabriel Comments On Article Discussing Pool Safety Tips for Parents 2
... 21 /PRNewswire/ Terumo Heart, Inc. today,announced the discharge of ... Assist System (LVAS). The patient was,discharged home on August ... after receiving the device., The patient is a ... heart failure for nearly 20 years. He is the ...
... have a study,that is falling behind with recruitment? Have ... media but still have not seen the,desired results? Perhaps ... to help,your sites navigate the world of media placements ... Argonauta Assist(TM) service," says Ms. Ann Kottcamp,President of Argonauta ...
Cached Medicine Technology:Discharge of First U.S. DuraHeart(TM) Patient 2Argonauta Assist(TM)ance: Argonauta Communications Strives to Enhance Site-Based Recruitment Efforts 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: