Navigation Links
Major variation in bladder cancer subtype trends highlights need for focused research
Date:1/4/2012

ancer cases. The majority of the patients (74%) were male and white (92%). Nearly two-thirds of the tumours (65%) were PTCC and 29% were TCC. The other 6% included squamous cell, adenocarcinoma and small cell carcinoma.
  • The overall age-adjusted incidence rates for bladder cancer fell by about 9% between 1973 and 2007 from 16.7 per 100,000 to 15.2. Similar trends were noted in both genders and racial groups.
  • However, significant differences emerged when the research team looked at the two main subtypes. While the age-adjusted rates for NPTCC fell by about 53%, from 7.9 per 100,000 in 1973 to 3.7 per 100,000 in 2007, PTCC increased by 56% from 6.8 to 10.6 per 100,000 over the same period. Similar trends were noted in both genders and racial groups and in different stages of the disease localised, regional and distant.
  • A dramatic increase in the incidence rates of grade four tumours was found between 1998 and 2007, with decreasing trends for grade one, two and three tumours. This is probably due to changes in the grading system introduced in 1998, but the lack of reduction in more aggressive bladder cancer is of great concern. Similar increases were observed for NPTCC and PTCC, genders, racial groups and different disease stages.

    "The striking differences in the trends between PTCC and NPTCC suggest that they may be two disease entitles with different causes" concludes Dr Zhang. "Recent survival analysis has also shown that survival rates are substantially higher for PTCC than NPTCC.

    "Despite this, no epidemiological studies have investigated the risk factors of these two subtypes separately. Our study suggests that future research must make clear distinctions between PTCC and NPTCC and not just treat them as subtypes of transitional cell carcinoma."


    '/>"/>

  • Contact: Annette Whibley
    annette.wizard@gmail.com
    Wiley-Blackwell
    Source:Eurekalert

    Page: 1 2

    Related medicine news :

    1. MP3 Players May Be Major Source of Hearing Loss
    2. Neuralstems NSI-189 trial in major depressive disorder receives FDA approval to advance to Phase Ib
    3. Majority of B.C. women take prescription drugs during pregnancy: UBC study
    4. Major cause of chronic kidney disease-related inflammation is identified
    5. Brain tsunamis are clue to helping victims of major head injuries
    6. Northern Ireland company makes major breakthrough in cancer treatment
    7. Major project to implement new treatments to boost kala-azar elimination strategies
    8. Earthquakes Put Millions of Lives, Major Cities at Risk
    9. How major signaling pathways are wired to our genome gives new insight into disease processes
    10. Policymakers should prepare for major uncertainties with Medicaid expansion
    11. Ghost Writing Persists in Major Medical Journals
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/7/2015)... , ... July 07, 2015 , ... ... provide payment parity for an expanded list of telehealth services available to Medicare ... from Representatives Gregg Harper (R-MS 3), Diane Black (R-TN 6) and Peter Welch ...
    (Date:7/7/2015)... ... July 07, 2015 , ... The ... a mark on the cosmetic surgery industry with its commitment, teamwork, and dedication ... VisitandCare.com partnered medical provider is committed to patient safety, world-class results, and compassionate ...
    (Date:7/7/2015)... York, NY (PRWEB) , ... July 07, 2015 , ... ... thing that can help pass those long, stressful days at work is knowing that ... aren’t always as laid back and stress free as imagined. Planning for a vacation ...
    (Date:7/7/2015)... ... July 07, 2015 , ... The United States Centers for ... of Massachusetts , and the Multicultural AIDS Coalition $3.78 million for a ... have sex with men (MSM) and transgender women, the groups at highest risk ...
    (Date:7/7/2015)... ... July 07, 2015 , ... SC&H Group, a leading audit, tax, ... give back to the community through company-wide volunteering efforts. , On an annual basis, ... day to assisting those in need throughout Baltimore and Washington D.C. , ...
    Breaking Medicine News(10 mins):Health News:The American Telemedicine Association Supports Legislation to Expand Medicare Coverage for Telemedicine Services 2Health News:Top Plastic Surgery Provider in Brazil Joins VisitandCare.com 2Health News:Top Plastic Surgery Provider in Brazil Joins VisitandCare.com 3Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 2Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 3Health News:CDC Awards Fenway Health, AIDS Action, Multicultural AIDS Coalition $3.78m For ‘Getting To Zero’ HIV Prevention Partnership 2Health News:CDC Awards Fenway Health, AIDS Action, Multicultural AIDS Coalition $3.78m For ‘Getting To Zero’ HIV Prevention Partnership 3Health News:SC&H Group Celebrates 9th Annual Day of Service 2
    ... international group of eating disorders say that the ... disorders is like blaming// parents for diabetes or ... statements by fashion model Gisele Bundchen stating that ... and further stigmatize eating disorders. ...
    ... than a dozen people have taken ill and have been ... ‘false’ and ‘ baseless’ by spokesman Xiong Yuanda of the ... was no infectious ‘unknown’ disease, doing the rounds in the ... the Health bureau has sought to dispel reports carried by ...
    ... AIDS Healthcare Foundation on Monday is expected to file ... pharmaceutical company Pfizer//. The decision is the outcome for ... Viagra in advertisements, Reuters reports. ,According to ... increased risky sexual behavior, as well as cases of ...
    ... Kochi: In its efforts to promote Kerala as an ideal destination ... shows in the US, Britain, Dubai, Muscat, Kuwait, Sri Lanka and ... because it has to be systematic and we have asked the ... of the policy and when we announce it shortly we would ...
    ... in the Sydney CBD is linked to the Royal Automobile ... However, they could not confirm the link. ,Seven ... belonging to the Legionella family, Legionella pneumophilia, have been reported ... the Circular Quay area on New Year's Eve. ...
    ... University and pediatric specialists at Baylor College of Medicine have ... as passkeys that allows drugs to enter cancer cells. ... of the journal Organic and Biomolecular Chemistry. ,All ... Cell walls, or membranes, form a protective cocoon around the ...
    Cached Medicine News:Health News:'Families' - Doesn’t Cause Anorexia Nervos 2Health News:'Families' - Doesn’t Cause Anorexia Nervos 3Health News:AIDS Healthcare Foundation to File Lawsuit Against Pfizer 2Health News:Buckyballs Used as 'Passkey' into Cancer Cells 2
    (Date:7/7/2015)... Research and ... of the "Biomedical Photoacoustic Imaging Patent ... This patent landscape focuses on photoacoustic ... safe, non-invasive, non-ionizing imaging technique. The technique ... alternative to traditional medical imaging approaches. The ...
    (Date:7/7/2015)... VIEJO, Calif. , July 7, 2015 /PRNewswire/ ... company focused on developing innovative devices for the ... R. Michael Kleine has joined its Board ... over 25 years of medical device and healthcare ... biomedical companies where he has commercialized numerous leading-edge ...
    (Date:7/7/2015)... Accelovance, Inc. (Accelovance), a global contract ... General Medicine announced the completion of enrollment and ... Therapeutics, Inc. for the Phase 3 trial of ... SUSTOL® (granisetron injection, extended release) as part of ... receptor antagonist fosaprepitant and IV corticosteroid dexamethasone ...
    Breaking Medicine Technology:Worldwide Biomedical Photoacoustic Imaging Patent Landscape Report 2015 2Worldwide Biomedical Photoacoustic Imaging Patent Landscape Report 2015 3Sequent Medical Appoints Mike Kleine to its Board of Directors 2Sequent Medical Appoints Mike Kleine to its Board of Directors 3Accelovance Completes Trial Enrollment and Delivery of Clinical Data for Heron Therapeutics' Phase 3 Trial 2
    ... , CHAPEL HILL, N.C., Nov. 25 ... chief executive officer, will present at the Piper Jaffray 21st ... 2009, at The New York Palace Hotel in New York ... company,s two leading antibiotic clinical programs for the treatment of ...
    ... , FRAMINGHAM, Mass. and SYDNEY, Nov. 25 HeartWare International, ... and provider of less invasive, miniaturized circulatory support technologies revolutionizing ... is scheduled to make an investor presentation at the 21st ... on Wednesday, December 2, 2009. The conference is being held ...
    Cached Medicine Technology:HeartWare to Present at 21st Annual Piper Jaffray Health Care Conference in New York City 2
    ... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    ... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    Medicine Products: