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Major grant advances UW's clinical and translational research enterprise
Date:9/18/2007

plex in the near future will further enhance our capabilities."

The institute will produce scientists trained in interdisciplinary research who understand the challenges and complexities of moving fundamental laboratory discoveries through clinical trials in patients to health studies in communities.

"Scientists have shown that taking an aspirin a day can reduce a person's risk of heart attacks, yet only about 60 percent of the people who could benefit use aspirin," explains institute Director Marc Drezner, professor of medicine and associate dean for clinical and translational research at the School of Medicine and Public Health. "Many complicated factors contribute to this breakdown in the translation of fundamental knowledge, and we have set up an expansive plan and structure to ameliorate the problem."

Type one translational research involves the transfer of basic laboratory science to controlled clinical trials, adds Drezner, while type two translational research involves community- and population-based studies that facilitate the transfer of discoveries from those clinical trials to the real world, where things are much less controlled.

"By concentrating on the latter, we hope to identify better ways to rapidly get new interventions to a greater proportion of the people who so badly need them," Drezner says.

To ensure that research responds to local health care needs statewide, ICTR will enhance clinical research networks such as the Wisconsin Network for Health Research, a collaboration between the four largest health care systems in the state that will provide opportunities for networked research throughout the state and will afford consumers and health care providers in Wisconsin access to all kinds of health and medical information. Existing community-based networks that examine single health problems-such as cancer and Alzheimer's disease-will also participate in network research activities.

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Contact: Dian Land
dj.land@hosp.wisc.edu
608-261-1034
University of Wisconsin-Madison
Source:Eurekalert

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