Navigation Links
Lombardi research teams hone in on treatments for osteosarcoma and Ewing's sarcoma
Date:4/20/2010

S is generally results from respiratory failure due to spread of cancer to the lungs. Ezrin is a protein in the cell that contributes to the biology of cancer, especially to its growth and spread to other body parts. Accumulating evidence from experimental animal models and human cases suggest that ezrin is a key factor in spread of OS cells. Here we report the discovery of two lead compounds that directly bind to ezrin protein and inhibit its function in multiple assays. These small molecules have the potential to prevent or treat OS spreading to the lungs and significantly improve survival of OS patients." - Glay Bulut

Authors: Glay Bulut, Kevin Chen, Eric Glasgow, Jeffrey A. Toretsky, and Aykut ren, Georgetown Lombardi Comprehensive Cancer Center; Sung-Hyeok Hong, Chand Khanna, Hyun-Shik Lee, and Ira Daar, National Cancer Institute.

To be presented: Monday, April 19, 2010 9:00 am - 12:00 pm ET; Exhibit Hall A-C, Poster Section 23; Board 3


'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Lombardis Shields leads special journal focused on tobacco research
2. GUMCs Lombardi Hosts Symposium Exploring Future of Cancer Research and Personalized Medicine
3. New research identifies modifiable risk factors for heart disease
4. Nuvo Research announces early redemption of 5% convertible debentures
5. Researcher to track spread of disease, malware and power outages
6. UCSF Researchers Identify Regulator of Human Sperm Cells
7. Octapharma Accepting Applications for Research Grants Through March 31
8. Valentine Tailgate Party for the Girls with Festive Ideas from Beauty Research
9. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
10. University of Maryland chemist receives Astellas Award for blindness prevention research
11. Developing a cyberinfrastructure for comparative effectiveness in cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... HealthDay Reporter FRIDAY, Oct. ... cold sores -- herpes simplex -- might increase the risk ... In fact, being a carrier of certain antibodies to the ... found. "The identification of a treatable cause [herpes ... said lead researcher Dr. Hugo Lovheim, an associate professor in ...
(Date:10/25/2014)... (HealthDay News) -- A large influx of international aid ... avoid tens of thousands of deaths from the widening ... Using a specially designed mathematical model, the ... in just one densely populated county of hard-hit Liberia ... Monrovia. The researchers said that if international aid ...
(Date:10/25/2014)... FRIDAY, Oct. 24, 2014 (HealthDay News) -- October,s shorter, ... as seasonal affective disorder, according to an expert. ... SAD, may feel overly tired, lack motivation and even ... SAD can lead to suicide, said Dr. Angelos Halaris, ... neurosciences at Loyola University Chicago Stitch School of Medicine. ...
(Date:10/22/2014)... On October 22, CBS will air an ... both fictional and real. The Charles E Holman ... to advocacy and philanthropy in the battle against Morgellons ... to impart truth and clarity about this misunderstood and ... misconceptions about Morgellons Disease (MD) and most ...
(Date:10/22/2014)... 2014 For Dr. Iris Hunter, a job ... an extension of her life’s mission. Her extensive experience in ... owner of FirstLight HomeCare, make it clear that Hunter’s mission ... that my work makes a difference in the lives of ... so after much research, I felt ready to start on ...
Breaking Medicine News(10 mins):Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 3Health News:Experts Predict 'Catastrophic' Ebola Epidemic in West Africa if Aid Delayed 2Health News:Dark Days Here for Folks With Seasonal Depression 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2
... treatment, study shows , TUESDAY, Jan. 26 (HealthDay News) ... to lower high blood glucose levels caused by corticosteroid ... study has found. , The death rate for septic ... is 60 percent within a short period, according to ...
... CHICAGO , Jan. 26 After a week of trial ... $1-million insurance policy on January 20, 2010 , to settle a ... the physician,s failure to timely diagnose bladder cancer. , In Russell v. ... Carmen Russell and Daniel Russell, Jr. , the wife and ...
... , International Guidelines Ensure Maximum Protection of Children ... Just weeks after the United Nations General Assembly adopted a resolution ... the international community is struggling to provide appropriate care and protection ... Haiti . The Guidelines are the first international document on ...
... NASHVILLE, Tenn. , Jan. 26 Saint ... clinical quality among the top five percent in the nation ... is one of only 269 hospitals that received this distinction ... , The study by HealthGrades, the leading independent healthcare ratings ...
... 26 President Obama will need several props to get ... a box of teabags, a paper shredder, and a new "No ... by taking the 2,074 page Senate health bill and stuffing it ... a 20-page bill in plain, honest English," says Betsy McCaughey ...
... heart defects (CHD) are the most common birth ... births with one third of affected children requiring ... combined with developmental expectations for independence, behavioral self-regulation ... identification of neurobehavioral symptoms in some survivors. A ...
Cached Medicine News:Health News:Intensive Insulin Therapy Won't Boost Septic Shock Survival 2Health News:Romanucci & Blandin, LLC, Reaches $1 Million Settlement in Medical Negligence Lawsuit 2Health News:International Community Calls for Prevention of Further Trauma in Haiti 2Health News:International Community Calls for Prevention of Further Trauma in Haiti 3Health News:Saint Thomas Hospital Ranked Top Five Percent in Nation for the Second Consecutive Year According to Quality Study 2Health News:Props for the President at His State of the Union Address 2Health News:Bypass procedure used during infant heart surgery does not impair later neurological outcomes 2
(Date:10/22/2014)... , October 22, 2014 Investor-Edge ... Inc. (NASDAQ: FOLD ), Progenics Pharmaceuticals Inc. ... THLD ), Idera Pharmaceuticals Inc. (NASDAQ: ... Free research on these five companies can be accessed ... 21, 2014, the NASDAQ Composite ended at 4,419.48, up ...
(Date:10/22/2014)... Calif. , Oct. 22, 2014  Paper ... products, has developed APLS ® Body Guard ... minimizes the spread of bacteria and virus while ... APLS Body Guard Bio features a rugged, external ... edges that create a leak-proof inner chamber that ...
(Date:10/22/2014)... , October 22, 2014 ... ), a clinical-stage pharmaceutical company focused on ... reported positive top-line clinical results from its Phase ... oral insulin capsules, to treat type 1 diabetes. The ... States under a U.S. Food and ...
Breaking Medicine Technology:Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 2Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 3Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 4Market Momentum on Biotech Stocks - Amicus Therapeutics, Progenics Pharma, Threshold Pharma, Idera Pharma, and Merrimack Pharma 5New, State-Of-The-Art Body Bag Minimizes The Spread Of Bacteria And Virus 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 4
... 2010 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. ("China-Biotics" or "the ... developer, manufacturer and distributor of probiotics products in ... Company,s research and development department presented at the ... Equipment seminar in Hangzhou, China on November 21st. ...
... (OTC Bulletin Board: GOVX ) (the "Company"), an ... Immunodeficiency Virus), has appointed David A. Dodd as Chairman of ... Hildebrand is stepping down as Chairman and will remain on ... a consultant to the Company. Mr. Dodd, age ...
Cached Medicine Technology:China-Biotics Attended National Probiotics Seminar 2China-Biotics Attended National Probiotics Seminar 3David A. Dodd Appointed Chairman of the Board of GeoVax Labs 2David A. Dodd Appointed Chairman of the Board of GeoVax Labs 3David A. Dodd Appointed Chairman of the Board of GeoVax Labs 4
... CCR Medical's Articulating Tip Laryngoscopes ... in the Industry. The articulating ... by providing an improved view ... and Fiber Optic styles. We ...
German Style MacIntosh Fiber Optic Blade Laryngoscopes...
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
CCR Medical fiberoptic green system laryngoscope handles., ,OUTSTANDING PERFORMANCE, QUALITY, AND PRICING MAKE OUR FIBEROPTIC SELECTION MOST ECONOMICAL....
Medicine Products: