Navigation Links
Lombardi research teams hone in on treatments for osteosarcoma and Ewing's sarcoma
Date:4/20/2010

, requiring minimal reagents and a higher-throughput format. Data from binding studies will help to predict and direct the design of more potent analogues." - Julie S. Barber-Rotenberg

Authors: Julie S. Barber-Rotenberg, Yali Kong, Nilan Schnure, Sivanesan Dakshanamurthy, Milton L. Brown, Hayriye V. Erkizan, Aykut Uren. and Jeffrey A. Toretsky, from Georgetown Lombardi Comprehensive Cancer Center; Peter Frazier, Cornell University

To be presented: Monday, April 19, 2:00 pm 5:00 pm; Exhibit Hall A-C, Poster Section 28; Board 14


Phage display identifies novel toxic binding peptides for the disordered oncoprotein EWS-FLI1 (Abstract #3412)

EMBARGO: Tuesday, April 20, 2010, 9 AM

Author's summary: "The EWS-FLI1 protein results from a tumor-specific chromosomal translocation and is uniquely expressed in Ewing's Sarcoma Family Tumors (ESFT). EWS-FLI1 is a disordered protein and thus presents opportunities for manipulating protein-protein interactions, some of which will be specific anti-tumor targets. By looking at and identifying various peptides and their cognate proteins, we can investigate the function of EWS-FLI1 in order to improve therapies for ESFT patients. The A1 peptide, which we focused on specifically, appears to directly bind to the EWS-FLI1 protein and lead to cell death in cells with the EWS-FLI1 fusion protein." - Lauren M. Jacobwitz

Authors: Lauren M. Jacobwitz, Hayriye V. Erkizan, Aykut ren, and Jeffrey A. Toretsky, Georgetown Lombardi Comprehensive Cancer Center

To be presented: Tuesday, April 20, 9:00 am 12:00 pm ET; Exhibit Hall A-C, Poster Section 18; Board 13


Small molecule inhibitors of ezrin as anti-metastatic agents in osteosarcoma (Abstract #1550)

EMBARGO: Monday, April 19, 2010; 9:00 am ET

Author's summary: "Our study is focused on developing new therapies for osteosarcoma (OS). OS is a very aggressive cancer of the bone. Death from O
'/>"/>

Contact: Karen Mallet
km463@georgetown.edu
215-514-9751
Georgetown University Medical Center
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Lombardis Shields leads special journal focused on tobacco research
2. GUMCs Lombardi Hosts Symposium Exploring Future of Cancer Research and Personalized Medicine
3. New research identifies modifiable risk factors for heart disease
4. Nuvo Research announces early redemption of 5% convertible debentures
5. Researcher to track spread of disease, malware and power outages
6. UCSF Researchers Identify Regulator of Human Sperm Cells
7. Octapharma Accepting Applications for Research Grants Through March 31
8. Valentine Tailgate Party for the Girls with Festive Ideas from Beauty Research
9. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
10. University of Maryland chemist receives Astellas Award for blindness prevention research
11. Developing a cyberinfrastructure for comparative effectiveness in cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/30/2015)... Cyclist Barry Haarde will commence ... World 2015: Piles of Miles” near San Francisco, ... hemophilia and encourage individuals to support needy hemophilic ... One Life supports nearly 1,200 impoverished children and ... direct sponsorships, scholarships and micro-enterprise grants. Hemophilia is ...
(Date:5/30/2015)... This year the National Lung ... to offer one of the most diverse perspectives with ... practices to diagnose, treat and manage patients with COPD. ... Conference is Interaction with Multidisciplinary Healthcare Professionals who ... of Patients with COPD," said Brian W. Carlin, MD, ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 Displays and Exhibits’ ... has lowered the price of hanging signs ; making ... signs that hang down from ceiling rigging points at a ... the trade show floor. These signs are very unique ... are additional costs for installation and dismantle labor and rigging ...
(Date:5/29/2015)... The science of hair restoration has taken ... the efforts of internationally recognized hair transplant surgeon Dr. ... hair restoration and manual FUE techniques to offer ... , A Follicular Unit Extraction (FUE) is ... grafts from the donor areas of a patient. ...
(Date:5/29/2015)... The Recovery Village at Palmer ... co-occurring mental health treatment facility, will host a ... general public on June 1st, and will begin ... at Palmer Lake will offer affordable detox, residential, ... and evidence-based therapies, in a luxurious setting designed ...
Breaking Medicine News(10 mins):Health News:Barry Haarde Cycles 4,000 Miles Across the USA for Hemophilia 2Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 2Health News:Pulmonary Horizons 2nd Annual COPD Conference Miami Hilton Downtown, July 17-19, 2015 Patient Centered Cross-Continuum Education to Improve the Care of Patients with COPD 3Health News:Displays and Exhibits Announces New Hanging Sign Supplier 2Health News:Los Angeles and Beverly Hills Hair Transplant Doctor Now Combines Robotic Hair Restoration (ARTAS) and Manual FUE Transplants for Maximum Hair Coverage 2Health News:Advanced Recovery Systems Announces the Opening of The Recovery Village at Palmer Lake 2
... tiny translucent egg nestled in the special laboratory gel was ... researchers to quietly celebrate. This was the first time anyone ... a tiny sac called a follicle, to a healthy and ... fully mature, it is ready to be fertilized. The ...
... ATLANTA, July 13 The Department of Defense has selected United ... provider for the South Region. This decision comes at the ... a year. , , (Logo: ... , After a Wednesday debriefing from the TRICARE Management ...
... , , PHOENIX, ... contract to continue providing military families access to high quality ... the Department of Defense (DoD). The contract enables TriWest to ... needs of 2.7 million active duty personnel, their families and ...
... (July 13, 2009) -- Physician-scientists from NewYork-Presbyterian Hospital/Weill Cornell ... growth factor in the blood may explain why blacks ... compared to whites. Results from a new study are ... a protein, called transforming growth factor B1 (TGF-B1), raises ...
... , Gail McG overn to Address ... , , WASHINGTON, July 13 Gail J. McGovern, ... a National Press Club Luncheon on Tuesday, July 21, 2009. The focus of ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20090108/RedCrossLOGO ) , , ...
... , , DALLAS , July 13 ... heart doc . One-fifth or more of young adults between ages 18-22 ... online in Circulation: Journal of the American Heart Association. , , ... , , , Another study ...
Cached Medicine News:Health News:New technique could save cancer patients' fertility 2Health News:New technique could save cancer patients' fertility 3Health News:New technique could save cancer patients' fertility 4Health News:TriWest Healthcare Alliance Awarded Third TRICARE Contract, Remains Health Care Contractor for Department of Defense in 21-State TRICARE West Region 2Health News:Why African-Americans are at greater risk of hypertension and kidney disease 2Health News:American Red Cross President to Address National Press Club Luncheon 2Health News:Young People With Heart Defects Not Checking In With Heart Doc 2
(Date:5/28/2015)... , May 28, 2015 Zimmer Holdings, ... it has finalized agreements with buyers to divest in ... Unicompartmental High-Flex Knee System assets, Biomet Discovery® Elbow System ... are in furtherance of Zimmer,s pending acquisition of Biomet, ... Zimmer continues to work constructively with the Bureau of ...
(Date:5/28/2015)... NEW YORK , May 28, 2015 ... billions developing new drugs and tests, and ... for the instruments that can assist them. This ... research publisher. Kalorama Information said instruments such as ... can assist in the identification of drug ...
(Date:5/28/2015)... -- Maetrics ( http://maetrics.com ), a leading international consulting firm ... successful conference, "The cost of non-compliance -- How new regulation ... Zurich . Hosted by ... Switzerland -based team, experts provided insights on the ... an exclusive local audience. The event was held in ...
Breaking Medicine Technology:Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 2Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 3Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 4Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 5Zimmer Announces Agreements in Furtherance of Pending Biomet Merger 6Report: Proteomics Research Market Reaches $1.6 Billion 2Report: Proteomics Research Market Reaches $1.6 Billion 3Maetrics Hosts Innovative Medical Cluster Event in Switzerland 2
... , HARTFORD, Conn., Dec. 16 ... home health benefits management services, announced today that it ... Washington, DC-based health care accrediting organization that establishes quality ... that only appropriately trained, qualified clinical personnel conduct and ...
... , , ... it was awarded the 2009 Top Innovator Presentation Award,in ... on December 8th,at Dedham, MA. The award, which recognizes ... granted to Biovista who competed with,over 50 other privately ...
Cached Medicine Technology:CareCentrix Receives URAC Health Utilization Management Accreditation 2Biovista Inc. Named Top Innovator in Life Sciences 2
Cruciate Retaining, Posterior Stabilized and Constrained Components....
... posterior stabilized knee has an advanced ... flange mates with both resurfacing and ... precise, repeatable kinematics and fit with ... reduce wear. Constant cutting guide peg ...
... system is a long term, ... clinically proven design. Available in ... correct cruciate retaining configurations. In ... of identification keeps the user ...
... CR System was designed to replicate ... joint has a recessed, deepened and ... of the patella, which has been ... anatomic groove promotes more normal kinematics ...
Medicine Products: