Navigation Links
Levels of Biomarkers After ACL Surgery May Signal Severity of Osteoarthritis Later in Life
Date:3/18/2017

Levels of Biomarkers After ACL Surgery May Signal Severity of Osteoarthritis Later in Life

San Diego, CA – A majority of Anterior Cruciate Ligament (ACL) reconstruction patients develop a condition known as posttraumatic osteoarthritis (PTOA) within 15 years of surgery, which can be debilitating and limit activity. Researchers presenting their work at the American Orthopaedic Society for Sports Medicine’s (AOSSM) Specialty Day in San Diego are highlighting how a set of biomarkers on the day of surgery may explain why some individuals have worse PTOA than others after two years.

“Previous studies demonstrated how ACL injury triggers a biochemical process that worsens after the first 4-6 weeks of injury. Our research notes that higher levels of collagen breakdown at the time of surgery, may correlate to worse outcomes at two years,” said lead author of the study, Christian Lattermann, MD of the University of Kentucky.

Lattermann and his colleagues studied 18 patients (9 females and 9 males ranging in age from 14 – 32 years) with an ACL injury. These individuals were previously enrolled in a prospective randomized trial evaluating early anti-inflammatory treatment after ACL injury. As part of the initial trial, synovial, serum, and urinary biomarkers of chondrodegeneration and inflammation were collected on the day of the surgery. The researchers utilized a variety of outcomes measures, including the KOOS-QOL scores to analyze results.

“Our data strongly suggests that initial biochemical changes after injury may have powerful consequences that cannot be mitigated by surgical stabilization alone,” notes Lattermann. “These results also create an opportunity to learn more about how early interventions with anti-inflammatory medications, may help lessen osteoarthritis risks in ACL patients, especially those patients with high levels of a particular biomarker.”

###

The American Orthopaedic Society for Sports Medicine (AOSSM) is a world leader in sports medicine education, research, communication and fellowship, and includes national and international orthopaedic sports medicine leaders. The Society works closely with many other sports medicine specialists, including athletic trainers, physical therapists, family physicians, and others to improve the identification, prevention, treatment, and rehabilitation of sports injuries. AOSSM is also a founding partner of the STOP Sports Injuries campaign to prevent overuse and traumatic injuries in kids.

Read the full story at http://www.prweb.com/releases/2017/03/prweb14148976.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related medicine news :

1. Why Dairy Proteins May Be the Answer to Controlling Insulin and Blood Glucose Levels
2. Pixel Film Studios Recently Released ProSlice Levels for Final Cut Pro X
3. Adults at Risk for Diabetes Double Activity Levels
4. 2016 ‘State of the Air’ Report Finds More than Half of Americans Live with Unhealthful Levels of Air Pollution
5. World Patent Marketing Invention Team Introduces Diakitex, a Breakthrough Medical Invention That Will Help Diabetic Patients Manage Their Blood Sugar Levels
6. Fowl Play: Research from airmid healthgroup Finds High Levels of Contaminants in Newly Purchased Feather and Down Bedding
7. WEDI Releases Industry Survey to Gauge Levels of Interest in Specific Healthcare Focus Areas
8. Study on Enzyme and Acid Levels adds Another Health Benefit to Bariatric Surgery, Notes Dr. Michael Feiz
9. Recent Bariatric Study Reveals Good News for Diabetic Patients of All BMI Levels, Notes Dr. Michael Feiz
10. InventHelp Inventor Develops Tester for Hormone Levels (LAX-426)
11. Cannabis Dispensary CEO Comments in Blog Posting on How Consumers Are Influencing the Potency Levels of Legal Marijuana
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , ... mock evacuation of the facility as part of a disaster drill on October 3rd. ... EMS and Shelton City Emergency Manager, as well as the Connecticut Long Term ...
(Date:10/13/2017)... ... 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out ... free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting ... children of all ages; it is a non-competitive, non-timed event, which is all about ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized health ... expanded their existing home health joint venture through an agreement, effective October 1, ... joint venture home health company with Asante, delivering clinically integrated care, for the ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... COUNTY, Calif. , Oct. 10, 2017  NDS received FDA ... Mobile  — a medical-grade battery-powered display stand specifically designed for endoscopy ... to transform technology into a clinical solution to support the improvement ... Innovative Design ... ZeroWire Mobile Wireless Solution ...
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
(Date:10/4/2017)... OBP Medical , a leading ... today announced regulatory approval from Brazil,s ... Nacional de Vigilância Sanitária (ANVISA)) to market ... with integrated LED light source and smoke evacuation ... of a tissue pocket or cavity during surgical ...
Breaking Medicine Technology: