Navigation Links
Let there be tissue-penetrating light: Scientists develop new nanoscale method to fight cancer
Date:2/28/2014

Researchers from UCLA's Jonsson Comprehensive Cancer Center have developed an innovative cancer-fighting technique in which custom-designed nanoparticles carry chemotherapy drugs directly to tumor cells and release their cargo when triggered by a two-photon laser in the infrared red wavelength.

The research findings by UCLA's Jeffrey Zink, a professor of chemistry and biochemistry, and Fuyu Tamanoi, a professor of microbiology, immunology and molecular genetics, and their colleagues were published online Feb. 20 in the journal Small and will appear in a later print edition.

Light-activated drug delivery holds promise for treating cancer because it give doctors control over precisely when and where in the body drugs are released. Delivering and releasing chemotherapy drugs so that they hit only tumor cells and not surrounding healthy tissues can greatly reduce treatment side effects and increase the drugs' cancer-killing effect. But the development of a drug-delivery system that responds to tissue-penetrating light has been a major challenge.

To address this, the teams of Tamanoi and Zink, which included scientists from the Jonsson Cancer Center's cancer nanotechnology and signal transduction and therapeutics programs, collaborated with Jean-Olivier Durand from France's University of Montpellier to develop a new type of nanoparticle that can absorb energy from tissue-penetrating light.

These new nanoparticles are equipped with thousands of pores, or tiny tubes, that can hold chemotherapy drugs. The ends of the pores are capped with nanovalves that keep the drugs in, like a cork in a bottle. The nanovalves contain special molecules that respond to energy from two-photon light exposure, which prompts the valves to open and release the drugs.

The operation of the nanoparticles was demonstrated in the laboratory using human breast cancer cells.

Because the effective range of the two-pho
'/>"/>

Contact: Shaun Mason
smason@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dr. Carol Francis Radio Talk Show Discusses Sexual Abuse as Related to "Coach" Jerry Sandusky; Interview With Abuse Survivor Teresa Joyce, Author of "There's A Fine Line"
2. New findings by GW researcher break tanning misconceptions: There is no such thing as a safe tan
3. Are there gender differences in anti-HIV drug efficacy?
4. Theres an app for that: Apple iPod Touch helps adults with autism function in the workplace
5. Youth with autism gravitate toward STEM majors in college -- if they get there
6. Are there racial disparities in osteoporosis screening and treatment?
7. Predicting risk of arrhythmias and sudden cardiac death: Theres a computer model for that
8. Is there a period of increased vulnerability for repeat traumatic brain injury?
9. Why are there redheads? Birds might hold the clues
10. When It Comes to Spine Surgery, There Is No July Effect: Study
11. Theres room for improvement in womens heart disease awareness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... ... July 02, 2015 , ... The American Association of ... the Stop Overdose Stat (S.O.S.) Act of 2015 on June 23, 2015. Together ... seeks to decrease drug overdose – especially of heroin and opioid medication – ...
(Date:7/2/2015)... ... July 02, 2015 , ... Many Fourth of July celebrations will ... Amica Insurance is sharing some tips to promote the proper use of ... go to the emergency room daily with fireworks-related injuries in the month surrounding the ...
(Date:7/2/2015)... , ... July 02, 2015 , ... In 2012, Patrick Achebe realized that the gift ... alone. He sat down to write his first poem, and three years later he was ... was special and worth sharing with the world. "I have always believed that the best ...
(Date:7/2/2015)... (PRWEB) , ... July 02, 2015 , ... As Americans ... like the hot temps, skin cancer is on the rise. July is UV Safety ... are raising awareness about the importance of getting skin checks. Experts say most skin ...
(Date:7/2/2015)... ... ... Global leader and compression innovator, SIGVARIS North America, is proud ... style that’s quick on its feet, men will love this fun new way to ... because a simple change in socks can dramatically help improve overall leg health by ...
Breaking Medicine News(10 mins):Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 3Health News:6 Fireworks Safety Tips from Amica Insurance 2Health News:Patrick Achebe Releases Debut Book, Whispering Waves: Poems for Everyday Grace 2Health News:Local Physicians Warn of Holiday Health Hazards 2Health News:Local Physicians Warn of Holiday Health Hazards 3Health News:Local Physicians Warn of Holiday Health Hazards 4Health News:SIGVARIS Kicks Up Its Style for Men with the Launch of MIDTOWN MICROFIBER in a Dark Navy Stripe Pattern 2Health News:SIGVARIS Kicks Up Its Style for Men with the Launch of MIDTOWN MICROFIBER in a Dark Navy Stripe Pattern 3
... ... with the Saint Louis University Department of Pharmacology and Physiology -- a $974,024 National ... approaches in treating neuroinflammation. , ... Edwardsville, Ill. (Vocus) November 2, 2009 -- The Southern Illinois ...
... Helps Heal Fractures , ROSEMONT, Ill., Nov. 2 ... to as "nonunion" can develop. This occurs when the ... to a new study published in the November 2009 issue ... (JBJS) , certain cases involving nonunions respond very well ...
... Cross Blue Shield of Michigan and Oncology Physician Resource ... initiative aimed at enhancing the quality of care for ... OPR, a statewide physician organization comprised of 140 oncologists ... leaders from across Michigan, as well as P4 Healthcare, ...
... ... companies are in need of translation services for the first time. Avantpage has responded ... the process of obtaining, coordinating, and evaluating translation services. , ... Davis, CA (Vocus) November 2, 2009 -- ...
... ... a certifying body upon the release of the Office of the National Coordinator for Health ... has been approached recently by numerous EHR software and services companies that need to be ... Fort Worth, TX ...
... Vanda Pharmaceuticals Inc. (Vanda) (Nasdaq: VNDA ), a biopharmaceutical ... for central nervous system disorders, today announced financial and operational ... , Vanda reported a net loss of $7.7 million ... for the second quarter of 2009 and $10.9 million for ...
Cached Medicine News:Health News:SIUE School of Pharmacy, SLU Pharmacology Receive $975K NIH Grant 2Health News:SIUE School of Pharmacy, SLU Pharmacology Receive $975K NIH Grant 3Health News:SIUE School of Pharmacy, SLU Pharmacology Receive $975K NIH Grant 4Health News:New Study Finds Shock-Wave Therapy for Unhealed Fractured Bones as Effective as Surgery 2Health News:New Study Finds Shock-Wave Therapy for Unhealed Fractured Bones as Effective as Surgery 3Health News:Blue Cross Blue Shield of Michigan and Michigan Oncologists Launch Statewide Initiative to Create Cancer Guidelines 2Health News:Blue Cross Blue Shield of Michigan and Michigan Oncologists Launch Statewide Initiative to Create Cancer Guidelines 3Health News:10 Ways to Get the Most out of Your Translation Service: Avantpage Reports on Industry Best Practices 2Health News:Drummond Group Plans to Certify Electronic Health Records 2Health News:Drummond Group Plans to Certify Electronic Health Records 3Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 2Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 3Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 4Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 5Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 6Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 7Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 8Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 9Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 10Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 11Health News:Vanda Pharmaceuticals Reports Third Quarter 2009 Results 12
(Date:7/2/2015)... DUBLIN , June 25, 2015 /PRNewswire/ ... http://www.researchandmarkets.com/research/8mfjxh/2015_new ) has announced the addition of ... Chemistry and Immunodiagnostics: Global Challenges, Emerging Technologies, ... 2015 New Frontiers in Clinical ... Competitive Landscape is a new seven-country strategic ...
(Date:7/2/2015)... China , 2. Juli 2015 ... für DNA-Screening in Hongkong vom American College ... in Hongkong ist das erste klinische Next-Generation-Sequencing ... ein CAP-Zertifkat erhält und somit die ... zu den bestehenden US FDA - 21 ...
(Date:7/2/2015)... Va. , July 2, 2015  The ... an agreement with ASHP, an organization that represents ... as a provider of continuing education for recertification ... designated track of geriatric programs for this purpose.  ... Pharmacists as authorized providers for the CCGP Professional ...
Breaking Medicine Technology:New Frontiers in 2015 Global Clinical Chemistry and Immunodiagnostics Market: Challenges, Emerging Technologies, Competitive Landscape 2BGI erhält Akkreditierung vom College of American Pathologists (CAP) 2Commission for Certification in Geriatric Pharmacy Adds ASHP as Professional Development Program Provider 2
... anti-mail-service pharmacy legislation, New York Governor Andrew Cuomo announced ... to amend NY AB 5502-B, which prevents employers from ... cost mail-service pharmacy option. "Employers, taxpayers, ... to improve this costly, anti-consumer bill," said Pharmaceutical ...
... RIDGE, Colo., Dec 13, 2011 MedEfficiency, Inc., ... the development, manufacturing, and marketing of medical devices ... today announced that it has been awarded a ... contract, MedEfficiency will be listed as a government-approved ...
Cached Medicine Technology:PCMA: Governor Cuomo's Call to Amend Anti-Mail-Service Pharmacy Law Protects Employers and Consumers 2PCMA: Governor Cuomo's Call to Amend Anti-Mail-Service Pharmacy Law Protects Employers and Consumers 3MedEfficiency Awarded VA Contract for Its Total Contact Casting Products 2
... Achieve high-speed productivity in the lab ... system, dedicated for pre- and post-analytical sorting ... HSS selectively decaps and then sorts primary ... to save time, labor, and eliminate ...
... Catering to the special needs ... Infant ThermoWrap™ protects the littlest ... their most vulnerable by providing ... continuous management of an infants ...
Cocoon Disposable Patient Warming Blankets are specially designed to prevent hypothermia and maintain normothermia in your patients. The soft warm coloured material is strong and resists tearing and ...
A smaller version of the Model 525 lower body blanket, this blanket is ideal for warming the large child or small adult during upper body surgery....
Medicine Products: