Navigation Links
Kidneys Sometimes Removed Needlessly in Patients With Rare Genetic Disorder
Date:1/11/2013

s can be disfiguring and distressing. And in some cases, angiomyolipomas lying on the kidneys can grow so large they disrupt kidney function.

But not all doctors are familiar with tuberous sclerosis, so they might mistake those growths for something more insidious.

"I had a [pediatric] patient who came to me a couple of years ago," Rabenou said. "She had angiomyolipomas in her kidneys -- and you can get massive amounts of tumors in the kidneys, sometimes you can't even see the kidneys. She went to a urologist at a major hospital nearby and was told she needed one-and-a-half kidneys removed."

Luckily, the patient was also taken to Rabenou, a specialist in tuberous sclerosis. "I told the parents I would just leave her alone," he said. "I would do an angiography and embolize the angiomyolipomas [to reduce bleeding] but I certainly would not take out her kidneys."

In other cases, Rabenou said, a partial removal of the kidney -- for example, the tissue next to an external angiomyolipoma -- would suffice instead of total removal of the organ.

Tuberous sclerosis has long been difficult to treat. But that might change: An international study published Jan. 10 in The Lancet found that the drug everolimus (Afinitor) was successful in treating kidney complications in some cases of tuberous sclerosis or a related condition.

The new study was led by Dr. John Bissler, chair of nephrology at Cincinnati Children's Hospital Medical Center, and involved adults with at least one large kidney angiomyolipoma. Participants were randomly assigned to either take everolimus or inactive placebo pills daily for about 38 weeks.

Ninety-eight patients completed the study. Of those on everolimus, 42 percent had their tumors reduced by at least half. None of the placebo patients had this response.

Novartis, the maker of everolimus, funded the study, and several of the authors are Novartis consultants.

"The drug is a big breakthrough
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study
2. Treating Kidneys With Radio Waves May Ease Tough-to-Control Hypertension
3. Kidney cancer patients do better when whole kidney is not removed, U-M study shows
4. Black Patients More Apt to Have Voice Box Removed When Cancer Strikes
5. Higher-spending hospitals have fewer deaths for emergency patients
6. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
7. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
8. Study finds doctors have exaggerated fears when starting patients on insulin
9. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
10. Predictors identified for rehospitalization among post-acute stroke patients
11. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidneys Sometimes Removed Needlessly in Patients With Rare Genetic Disorder
(Date:4/27/2015)... Beckman Coulter is sponsoring a ... the evolution of neural circuitry and swimming behavior of ... mechanisms by which analogous forms of swimming behavior, such ... independently in certain sea slug clades. The webinar is ... 30, 2015 at 8:00am PT. , Sea slugs (Mollusca, ...
(Date:4/27/2015)... April 27, 2015 Sitting or standing for ... and feel tired, and for those whose occupation requires them ... and taxi cab drivers, or to be on their feet ... the discomfort can be more severe and longer lasting. These ... syndrome. Dr. Madaiah Revana of Northeast Houston Vein Center is ...
(Date:4/27/2015)... 27, 2015 FMC Corporation’s Health and ... wide range of market leading ingredients and solutions at ... Geneva, Switzerland. Vitafoods Europe 2015 expects to host 14,000 ... the latest research in such areas as digestive health, ... FMC Health and Nutrition’s booth will feature its world ...
(Date:4/27/2015)... 27, 2015 Telematics Berlin is Europe’s ... suppliers, associations, CE players and the government to discuss ... to the car. This year’s panel on connected car ... the European Commission, is an opportunity to hear and ... a European Automotive Security Standard for years to come. ...
(Date:4/27/2015)... Mirada, CA (PRWEB) April 27, 2015 ... minimally invasive treatments for nail fungi and infections. Onychomycosis, ... to affect up to 10% of adults in the ... fragility, and irregularity in thickness. , Healthpointe’s ... Institute , a branch dedicated to providing quality skincare ...
Breaking Medicine News(10 mins):Health News:Beckman Coulter Genomics Presents Using Next-Gen Sequencing to Study the Evolution of Neural Circuitry 2Health News:Beckman Coulter Genomics Presents Using Next-Gen Sequencing to Study the Evolution of Neural Circuitry 3Health News:Northeast Houston Vein Center Offers Tips on How to Treat Achy Legs 2Health News:Northeast Houston Vein Center Offers Tips on How to Treat Achy Legs 3Health News:FMC Health and Nutrition to Feature Epax® Brand Omega-3 Ingredients at Vitafoods Europe 2015 2Health News:Telematics Berlin: European Commission discuss a pan European Automotive Security Strategy 2Health News:Telematics Berlin: European Commission discuss a pan European Automotive Security Strategy 3Health News:Southern California Healthpointe Clinics Now Treating Nail Fungus 2
... offered to manufacture an antiviral drug for bird flu called ... It has already made Tamiflu in its lab. // , ... popular as Tamiflu has but is cheaper and sometimes a ... Cipla in a press release said:‘‘Zanamivir is the only other ...
... as the first most common cause for death in ... stress echocardiography that can help predict life-threatening heart problems ... conducted among a group of diabetic women aged between ... type of stress test for suspected coronary disease that ...
... an increasing attention is being directed towards cost-effective treatment ... chiropractic care produces significantly // better outcomes when compared ... higher pain relief and satisfaction and lower disability scores ... ,The study has been conducted in the American population ...
... a hand-held scope called VELscope, which has been developed by ... of Dental Craniofacial Research. The devise emits a blue light ... detection of cancerous lesions in the mouth. The VELscope would ... better treatment is achieved when oral cancer is treated in ...
... Livermore National Laboratory are studying the biopolymer structural dynamics ... The new theory on protein folding unfolds the mystery ... leads to diseases and the study is to be ... of Sciences. , ,The researchers used a technique ...
... sclerosis patients in Britain can look forward to some relief, ... for the first time, following approval from the Home Office ... Britain will soon be able to obtain an unlicensed, cannabis-based ... arthritis even though it is yet to be licensed in ...
Cached Medicine News:Health News:Cipla In India Can Manufacture Drug For Bird Flu 2Health News:Cipla In India Can Manufacture Drug For Bird Flu 3Health News:A Simple Test To Detect Heart Disease In Women Can Be Lifesaving 2Health News:Back Pain Can Now Be Cost-Effectively Treated By Chiropractic Care 2Health News:Relief For British MS Patients: Cannabis-Based Oral Spray 2
(Date:4/27/2015)... MILAN , April 27, 2015  USL di ... Italian province of Reggio Emilia, has implemented Zebra ... throughout the hospital. The Wireless Network Solution ... patients, medical records securely and in real time via ... available at all times. Zebra also provides employee and ...
(Date:4/27/2015)... SAN DIEGO , April 27, 2015  Agena Bioscience ... (CSP) for Agena Bioscience,s MassARRAY platform in China ... at unprecedented speed. It is a hotbed for practical, meaningful ... China and for the rest of the world. ... community in China ," said Peter ...
(Date:4/27/2015)... -- China Jo-Jo Drugstores, Inc. (NASDAQ CM: ... leading China-based retail and wholesale distributor that offers pharmaceutical ... pharmacies, today announced its subsidiary, Hangzhou Jiuzhou Grand Pharmacy ... sales incentive agreement with Wyeth Pharmaceutical Company, Ltd. ("Wyeth"), ... of Pfizer Inc. (NYSE: PFE ) (the ...
Breaking Medicine Technology:Zebra Technologies' Wireless Solutions Help Reggio Emilia Hospital Staff Improve Patient Care and Reduce Costs 2Zebra Technologies' Wireless Solutions Help Reggio Emilia Hospital Staff Improve Patient Care and Reduce Costs 3Zebra Technologies' Wireless Solutions Help Reggio Emilia Hospital Staff Improve Patient Care and Reduce Costs 4Zebra Technologies' Wireless Solutions Help Reggio Emilia Hospital Staff Improve Patient Care and Reduce Costs 5Agena Bioscience Names Bioyong Technology as Fifth Certified Service Provider in China 2China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 2China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 3China Jo-Jo Drugstore Signed a New Sales Incentive Agreement with Wyeth Pharmaceutical, a Subsidiary of Pfizer 4
... Disease Week ... 2008, ... today that it has initiated the Phase 2 clinical,development program of MDX-1100, ... ulcerative colitis (UC) and,rheumatoid arthritis (RA). MDX-1100 could potentially treat UC and ...
... Thailand, May 9 An emergency,veterinary team from the ... stand-by in Thailand awaiting authority to enter cyclone struck,Myanmar ... of animals,that human survivors depend on for food and ... The Food and Agriculture,Organization of the United Nations (FAO) ...
Cached Medicine Technology:Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis 2Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis 3Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis 4Animals That Cyclone Survivors Depend on Need Help Now 2
Inquire...
Inquire...
Inquire...
The modular, high-end stereomicroscope; meets even the most critical demands in research and quality control provides high-contrast images with excellent depth of field and color fidelity...
Medicine Products: