Navigation Links
Kidneys Sometimes Removed Needlessly in Patients With Rare Genetic Disorder
Date:1/11/2013

s can be disfiguring and distressing. And in some cases, angiomyolipomas lying on the kidneys can grow so large they disrupt kidney function.

But not all doctors are familiar with tuberous sclerosis, so they might mistake those growths for something more insidious.

"I had a [pediatric] patient who came to me a couple of years ago," Rabenou said. "She had angiomyolipomas in her kidneys -- and you can get massive amounts of tumors in the kidneys, sometimes you can't even see the kidneys. She went to a urologist at a major hospital nearby and was told she needed one-and-a-half kidneys removed."

Luckily, the patient was also taken to Rabenou, a specialist in tuberous sclerosis. "I told the parents I would just leave her alone," he said. "I would do an angiography and embolize the angiomyolipomas [to reduce bleeding] but I certainly would not take out her kidneys."

In other cases, Rabenou said, a partial removal of the kidney -- for example, the tissue next to an external angiomyolipoma -- would suffice instead of total removal of the organ.

Tuberous sclerosis has long been difficult to treat. But that might change: An international study published Jan. 10 in The Lancet found that the drug everolimus (Afinitor) was successful in treating kidney complications in some cases of tuberous sclerosis or a related condition.

The new study was led by Dr. John Bissler, chair of nephrology at Cincinnati Children's Hospital Medical Center, and involved adults with at least one large kidney angiomyolipoma. Participants were randomly assigned to either take everolimus or inactive placebo pills daily for about 38 weeks.

Ninety-eight patients completed the study. Of those on everolimus, 42 percent had their tumors reduced by at least half. None of the placebo patients had this response.

Novartis, the maker of everolimus, funded the study, and several of the authors are Novartis consultants.

"The drug is a big breakthrough
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study
2. Treating Kidneys With Radio Waves May Ease Tough-to-Control Hypertension
3. Kidney cancer patients do better when whole kidney is not removed, U-M study shows
4. Black Patients More Apt to Have Voice Box Removed When Cancer Strikes
5. Higher-spending hospitals have fewer deaths for emergency patients
6. Researchers uncover a viable way for colorectal cancer patients to overcome drug resistance
7. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
8. Study finds doctors have exaggerated fears when starting patients on insulin
9. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
10. Predictors identified for rehospitalization among post-acute stroke patients
11. Pulse pressure elevation could presage cerebrovascular disease in Alzheimers patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidneys Sometimes Removed Needlessly in Patients With Rare Genetic Disorder
(Date:5/21/2013)... on a large scale is the cornerstone of ... better outcomes, better value and better experience of ... patient-centered medical home model offers a viable solution ... of Health and Human Services, Agency for Healthcare ... more about the processes and determinants of successful ...
(Date:5/21/2013)... 2013 Mecklenburg EMS Agency (Medic) ... a free Community Wellness Fair to educate the public on ... be held on Wednesday, May 22, 2013 from 4:00 pm ... (8100 Old Mallard Creek Road, Charlotte, NC 29262). ... and the Mecklenburg County Department of Social Services ...
(Date:5/21/2013)... 21 May 2013, Paris, France: The Orsiro stent, ... from a biodegradable polymer, demonstrated non-inferiority to the ... endpoint of in-stent late lumen loss at nine ... reported at EuroPCR 2013 today. , The BIOFLOW-II ... tomography (OCT) to quantitatively assess neointimal hyperplasia and ...
(Date:5/21/2013)... Boca Raton, Fla. (PRWEB) May 21, 2013 ... TV program distributed on cable networks and cable channels ... of new episodes on its YouTube channel. The producers ... profiles of companies in the shipping industry, the manufacturing ... program highlights pioneering medical facilities and medical practitioners in ...
(Date:5/21/2013)... 2013 MedMar Healing Center announces ... Second Harvest Food Bank. Twenty-eight businesses, including MedMar Healing Center, ... food drive. The goal is to raise food to help ... facing their families in recent years. , “We like ... those in need,” explains Douglas Chloupek of MedMar Healing Center. ...
Breaking Medicine News(10 mins):Health News:AHRQ-funded journal supplement offers lessons on primary care practice transformation 2Health News:AHRQ-funded journal supplement offers lessons on primary care practice transformation 3Health News:AHRQ-funded journal supplement offers lessons on primary care practice transformation 4Health News:AHRQ-funded journal supplement offers lessons on primary care practice transformation 5Health News:AHRQ-funded journal supplement offers lessons on primary care practice transformation 6Health News:Mecklenburg EMS Agency Teams Up with the YMCA of Greater Charlotte and Others to Educate the Public on Health Related Initiatives 2Health News:Biodegradable stent proves non-inferior to drug-eluting stent 2Health News:In View hosted by Larry King Announces New Videos on its YouTube Channel 2Health News:San Jose Cannabis Club Helps Feed Hungry Children with Second Harvest Food Bank 2
... of developing another tumor stays high throughout life, study finds ... cancer as children face a high lifelong risk for developing ... that appears online May 26 in the Journal of ... studies by following people from birth through age 79. The ...
... funded by pharmaceutical company finds benefits in Abraxane, , , ... affirms that the chemotherapy drug Abraxane is more effective, ... of choice for metastatic breast cancer. , When compared ... by almost seven months, effectively doubling survival. Both are ...
... migraine have strong reason for new optimism concerning a ... "The Future of Migraine: Beyond Just Another Pill," in ... are the basis for an ironic premise. , "Migraine ... patients, families, workplaces, and society," according to the editorial ...
... May 26 The Medical Center of ... in half after an improvement project along the entire ... in June 2008. Medical Center leadership initiated the ... Emergency Department became evident. To help create a strategy ...
... how to avoid them , ... (Vocus) May 26, 2009 -- Avoiding ... you can save a great deal of money in medical expenses, says ... Medical Foundation ( www.petsafetyct.org ) and director of the Connecticut State Animal ...
... reduce the spread of HIV and other sexually ... diverse populations continues to be complex and challenging. ... two-year grant to David Prez-Jimnez, Ph.D., at the ... and assessment of an HIV and other sexually ...
Cached Medicine News:Health News:Drug May Extend Life When Breast Cancer Spreads 2Health News:Drug May Extend Life When Breast Cancer Spreads 3Health News:Mayo Clinic Proceedings: The evolution of migraine from episodic headache to chronic disorder 2Health News:Compirion Healthcare Cuts Emergency Department Throughput by 50% at the Medical Center of Central Georgia 2Health News:Compirion Healthcare Cuts Emergency Department Throughput by 50% at the Medical Center of Central Georgia 3Health News:Compirion Healthcare Cuts Emergency Department Throughput by 50% at the Medical Center of Central Georgia 4Health News:Compirion Healthcare Cuts Emergency Department Throughput by 50% at the Medical Center of Central Georgia 5Health News:CVMF Advises on How to Save Money on Veterinary Bills 2Health News:CVMF Advises on How to Save Money on Veterinary Bills 3Health News:CVMF Advises on How to Save Money on Veterinary Bills 4Health News:HIV prevention program gets a boost from NIMH recovery act funds 2
(Date:5/22/2013)... 22, 2013 /PRNewswire-iReach/ -- MarketReportsOnline.com announces addition of ... Series (4) 2013 Edition Material and Clinical Trial ... Registration: A Guidebook of Registration Application for Imported ... its online database. The traditional medicines ... always regarded by occidental as mysterious medicines. Until ...
(Date:5/22/2013)... May 22, 2013 Rigel Pharmaceuticals, Inc. (Nasdaq: ... of three programs in development. The first program is ... R348, being developed by Rigel as a treatment for ... at oncology targets and are being conducted by corporate ... BerGenBio AS (BerGenBio) and a ligase inhibitor under development ...
(Date:5/22/2013)... NEWARK, Del. , May 22, 2013 /PRNewswire/ ... today announced the production of a vaccine candidate ... an independent third party laboratory using the iBioLaunch™ ... days as measured from initial antigen sequence information ... (Logo: http://photos.prnewswire.com/prnh/20120419/NY91086LOGO ) The ...
Breaking Medicine Technology:China Pharmaceutical Market Guidebook Series (4) 2013 Report 2China Pharmaceutical Market Guidebook Series (4) 2013 Report 3China Pharmaceutical Market Guidebook Series (4) 2013 Report 4China Pharmaceutical Market Guidebook Series (4) 2013 Report 5Rigel's R348 to Initiate Phase 2 Clinical Trial in Dry Eye 2Rigel's R348 to Initiate Phase 2 Clinical Trial in Dry Eye 3Rigel's R348 to Initiate Phase 2 Clinical Trial in Dry Eye 4iBio Technology Produces Vaccine Candidate for Recently Emerged H7N9 Influenza 2
... N.J., Nov. 9 Unwavering from its pursuit of ... climate, Lutronic, Inc., a leading developer of high quality ... fractional CO2 device priced at under $50,000. , ... to Lutronic,s fractional technology including scanning and stamping operation ...
... (NYSE Amex: KAD ), a leading provider of ... brand, has appointed Stephen Goldsmith to its Board of ... his resignation from the Board. , ... is the Daniel Paul Professor of Government and Director ...
Cached Medicine Technology:Lutronic(R) Unleashes the New MOSAIC CO2 2Arcadia Resources Names Stephen Goldsmith to Board of Directors 2Arcadia Resources Names Stephen Goldsmith to Board of Directors 3
Fine tying forceps, standard with smooth jaws. For 7-0 to 9-0 sutures....
Maumenee tying forceps is straight with concave-convex jaws and has a round handle with guide pin. For 8-0 to 11-0 sutures....
Anis tying forcep is extra delicate with smooth jaws, curved. For 9-0 to 11-0 sutures....
McPherson titanium tying forceps which is 5 mm long, smooth jaws and straight. Used for 8-0 to 11-0 sutures....
Medicine Products: