Navigation Links
Kidney cancer reveals its weak link
Date:2/18/2014

A team of researchers at Chalmers University of Technology has found that kidney cancer cells have a quite different metabolism than other types of malignancies. The findings pave the way for new methods of diagnosing kidney cancer at an early stage, a feat that had eluded researchers earlier, and thereby fresh approaches to treatment.

Cancer is a result of mutations in the genes of healthy cells. The transition to cancer cells involves a fundamental transformation of their metabolism, the way that they use nourishment and energy. The uninhibited growth of cancer cells is based on their particular metabolism.

The Chalmers researchers have explored the metabolism associated with ten types of cancer cells. When analyzing regulation of metabolism by healthy cells after having become malignant, the researchers made an unexpected discovery.

"One type of cancer stood out from all the rest," says Professor Jens Nielsen, who headed up the team. "Cells affected by kidney cancer reprogram their metabolism in a very special way, which is the weak link in the disease. What fascinated us most was that we can potentially measure this vulnerability by taking a simple blood sample."

In order to look more closely at possible methods of using metabolism to diagnose renal cell carcinoma the most common type of kidney cancer the Chalmers team has begun collaborating with researchers at a hospital in Padua, Italy.

"To determine whether our predictions are valid," Professor Nielsen says, "the hospital will conduct a clinical trial to analyze blood samples and urine specimens from kidney cancer patients. We anticipate that a simple method of deciding whether someone has kidney cancer will be available within a few years."

Early detection of kidney cancer significantly improves its prognosis. Surgery to prevent the malignancy from metastasizing can still be successful at that point. The study also suggests that a feasible long-
'/>"/>

Contact: Christian Borg
christian.borg@chalmers.se
46-317-723-395
Chalmers University of Technology
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Herbal Remedy Ingredient Tied to Cancer, Kidney Failure
2. Specific inhibition of autophagy may represent a new concept for treatment of kidney cancer
3. Kidney cancer patients do better when whole kidney is not removed, U-M study shows
4. Role of Screening, Monitoring in Early Kidney Disease Unclear
5. Kidney Cancer Patients Fare Better With Tumor Removal Only
6. Donor Kidney Re-Used in Second Patient After Failing in First
7. Routine Kidney Disease Screening Not Worthwhile, Experts Say
8. Surprising results for use of dialysis for kidney failure in developing world
9. Everyday fish oil capsule may provide kidney-related benefits
10. First, Second Kidney Transplants Have Similar Success: Study
11. Women fare better than men, but need more blood after kidney cancer surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Kidney cancer reveals its weak link
(Date:4/17/2014)... discovering a new mechanism that allows blood to enter ... Irvine and the Salk Institute have opened the door ... brain damage. , A complex and devastating neurological condition, ... reason for disability in the U.S. The blood-brain barrier ... material into the brain, causing the permanent deficits in ...
(Date:4/17/2014)... Alliance, a nonprofit organization that focuses on conservation and ... examining the current state of knowledge of the deadly ... global surveillance strategies to combat the emergence of infectious ... West Africa that has claimed the lives of 122 ... According to the World Health Organization (WHO), the deadly ...
(Date:4/17/2014)... off depression among retirees, particularly among those who live ... The Journals of Gerontology, Series B: Psychological Sciences and ... Use and Depression Among Retired Older Adults in the ... that Internet use reduced the probability of a depressed ... , Late-life depression affects between 5 and 10 million ...
(Date:4/17/2014)... YORK (17 April 2014) Population Council scientists and their ... safe, stable, and can prevent the transmission of multiple ... rectum in animals: HIV, herpes simplex virus 2 (HSV-2), ... the first data that the gel is effective against ... efficacy in the vagina against all three viruses of ...
(Date:4/17/2014)... Meaningful long-term survival is possible for selected patients ... treated with cytoreductive surgery with Hyperthermic IntraPeritoneal Chemotherapy, ... physicians at Wake Forest Baptist Medical Center. , ... experience with cytoreductive surgery and HIPEC, said lead ... 20 years, worth of patient data shows that ...
Breaking Medicine News(10 mins):Health News:Study IDs new cause of brain bleeding immediately after stroke 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:Internet use may cut retirees' depression 2Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2
... ... strongest and most effective libido/intimacy enhancement therapy called VaietTM 110/L-Arginine for men and VaietTM ... ... release of their exclusive Viagra/Arginine Intimacy Enhancement Therapy or VAIET (named after their clinical ...
... a deep Michigan tradition of manufacturing to develop ... , DETROIT, June 15 EnovateIT, a national provider of ... internally designed, developed, and assembled Medical Computing Cart ... from admissions and operating rooms to patient rooms - improving ...
... bring colleges and their surrounding neighborhoods together may ... suggests. Researchers found that an alcohol control ... the community -- including increased police patrols in ... parties, combined with efforts to make off-campus students ...
... ... ... June 14, 2009 -- "Thomas McKeever has been selected by Jackson & Coker ... approach to physician staffing at prominent hospitals and large health care organizations across ...
... ... Donor Day , ... 14, 2009 -- Millions of people around the world owe their lives to individuals they will ... a Mercy Ship live and work just minutes away from the patients who receive their "gift ...
... brain damage can occur, , SUNDAY, June 14 (HealthDay News) ... riveted people,s attention to the issue of brain injury and ... to you or a loved one. , Richardson died hours ... resort. She picked herself up from the fall and refused ...
Cached Medicine News:Health News:After 10 Years A Stronger and More Enhanced Form of Viagra Now Available 2Health News:After 10 Years A Stronger and More Enhanced Form of Viagra Now Available 3Health News:After 10 Years A Stronger and More Enhanced Form of Viagra Now Available 4Health News:EnovateIT Announces New Enovate Medical Cart Series 2Health News:EnovateIT Announces New Enovate Medical Cart Series 3Health News:Colleges, communities combat off-campus student drinking 2Health News:Thomas McKeever to Spearhead Jackson & Coker's National Accounts Division 2Health News:Thomas McKeever to Spearhead Jackson & Coker's National Accounts Division 3Health News:Mercy Ships Celebrates World Blood Donor Day 2Health News:Mercy Ships Celebrates World Blood Donor Day 3Health News:Mercy Ships Celebrates World Blood Donor Day 4Health News:For Every Blow to the Head, Quick Action Is Urged 2Health News:For Every Blow to the Head, Quick Action Is Urged 3
(Date:1/15/2014)... CAMBRIDGE, Mass. , Jan. 15, 2014  Zafgen, ... the unmet needs of severely obese patients, today ... of beloranib, a selective inhibitor of methionine aminopeptidase ... a severe form of genetic obesity.  These results ...
(Date:1/14/2014)... , Jan. 14, 2014 The Brandeis Medical Center, led ... a premier and affordable laser tattoo removal experience with ... Brandeis, focus is in providing high quality cosmetic services with cutting ... " Southern California has seen a ...
(Date:1/14/2014)... , Jan. 14, 2014 NineSigma , Inc., ... its Innovation Leadership Summit , May 14-16, 2014 ... Cleveland Ohio . This ... organizations committed to breakthrough achievements through open innovation. Participants ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4
... Cardica, Inc. (Nasdaq: CRDC ) today announced ... Proximal Anastomosis System will be featured in several demonstration ... and Hybrid Coronary Revascularization conference, a meeting jointly developed ... Joseph,s Hospital in Atlanta, Georgia. "This ...
... announced that it has received approval from the United ... 7,815,929) regarding a method for the preparation, storage and ... nature, the process of compounding suppositories is cumbersome, time-consuming ... Muni, founder, chairman, and CEO of CutisPharma, Inc. "Our ...
Cached Medicine Technology:Cardica's Automated Anastomosis Systems Featured at Advances In Robotic And Hybrid Coronary Revascularization Meeting 2Cardica's Automated Anastomosis Systems Featured at Advances In Robotic And Hybrid Coronary Revascularization Meeting 3CutisPharma Announces Issuance of an Additional Patent for Suppository Compounding 2
BD Persist Plus protective barrier skin preps with chlorhexidine in alcohol...
... Sterile Isopropyl Alcohol 70% USP and 10% ... as a topical antiseptic, anti-infective prior to ... removal of oils and fats from the ... AAMI/ANSI/ISO 11137 standards to contain a consistent ...
Aplicare's Prep Pads offer convenience, low cost, ease of use. The medium size is appropriate for most applications. Each package is terminally sterilized, ensuring the safest possible product for th...
IV Prep Swab Sticks are effective, easy to apply, dries quickly and reduces bacterial contaminations. They are ideal for preparation of the skin prior to a ventipuncture or injection....
Medicine Products: