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Injectable Vaccines More Effective for Adult Flu Than Nasal Sprays
Date:9/23/2009

said. "There could be situations, such as with a mismatched strain, in which the live attenuated could perform just as well, or perhaps even better, than the injected."

And what about for H1N1 swine flu vaccines?

With the swine flu, vaccines made with live attenuated virus may work just as well as injected vaccines because children and most adults have no antibodies or natural immunity to the new strain, Monto noted.

"We are totally susceptible," he said. "That's why we are having these school outbreaks with high attack rates."

More information

The U.S. Centers for Disease Control and Prevention has more on seasonal flu.



SOURCES: Arnold S. Monto, M.D., professor, epidemiology, University of Michigan School of Public Health, Ann Arbor; Kenneth Bromberg, M.D., director, Vaccine Research Center, The Brooklyn Hospital Center, New York City; Sept. 24, 2009, New England Journal of Medicine


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