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IRSF Receives 1 Million Dollar Matching Gift
Date:10/27/2009

d mental retardation. We invite anyone with a passion for curing neurological disorders to join our campaign to reverse Rett syndrome."

The campaign, announced during Rett Syndrome Awareness Month, also coincides with the 10-year anniversary of the breakthrough discovery of the causative MECP2 gene, which was made by the lab of IRSF-funded researcher and key advisor, Dr. Huda Zoghbi at Baylor College of Medicine. "The last several years have been filled with exciting developments in Rett syndrome research, and major progress has occurred in the biomedical research arena," said Dr. Antony Horton, Chief Scientific Officer of IRSF. "IRSF has played a critical role in advancing the most important scientific breakthroughs in the last decade, including Dr. Adrian Bird's pivotal research demonstrating the reversibility of Rett syndrome symptoms in mice. This exciting proof-of-concept makes us very optimistic about the possibility of pharmacological reversal of Rett syndrome. This aggressive fundraising campaign will provide a much needed boost for drug discovery and development for this purpose, and various target compounds are being identified for testing in a clinical setting."

Around the country, at major research institutions, is a community of scientists committed to curing Rett syndrome and other neurological disorders. They are in position to benefit from funding allocations being finalized by the IRSF's Scientific Review Board and the National Institutes of Health (NIH). The NIH is the largest single source of medical research funds in the world, and has great influence on shaping scientific research agendas. Decision-makers there are looking to support collaborative research aimed at securing significant clinical results, research that represents a partnership between patient advocates, basic researchers and industry.

With this in mind, the IRSF scientific staff and expert advisors from academia and industry recently developed a
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SOURCE International Rett Syndrome Foundation
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