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Hormone therapy offers potential protective effect against colon cancer in older women
Date:4/22/2009

current study, the investigators examined tumor tissue from 553 colorectal cancer patients, specifically looking for associations between self-reported hormone use and a specific DNA methylation pattern, called the CpG island methylator phenotype, or BRAF gene mutations. No associations were detected between hormone use and these molecular markers. Of note, the investigative team previously reported that certain environmental exposures, such as cigarette smoking, might increase colorectal cancer risk through DNA methylation pathways.


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Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

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