Navigation Links
Hormone therapy offers potential protective effect against colon cancer in older women
Date:4/22/2009

DENVER In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear.

The study, being presented at the AACR 100th Annual Meeting 2009, was designed to look at possible links between estrogen exposure and colon cancer molecular subtypes, to determine how these hormones might function as anti-cancer agents.

"In our large, prospective study, use of hormone therapy seemed to be beneficial with respect to reducing colorectal cancer risk women who did use these drugs had a 28 percent lower incidence rate than women who did not use these drugs," says the study's lead author, David Limsui, M.D., a fellow in the Department of Gastroenterology at Mayo Clinic's campus in Rochester, Minn. "But we still don't know how estrogen compounds work in cancer prevention, which is intriguing."

Women who reported using other hormone preparations, such as oral contraceptives, did not appear to derive any colorectal cancer prevention benefits. "Based on our findings, we need to continue exploring the cancer pathways that might be affected by these hormones," Dr. Limsui says.

He adds that other studies have also found that hormone therapy protects postmenopausal women against colon cancer. The largest randomized clinical trial was the 16,000-participant Women's Health Initiative, which concluded in 2004 that combination hormone therapy (estrogen and progestin) reduced a woman's risk of colorectal cancer by about 40 percent, he says. "But few studies have delved deeper to see how these hormones work at the molecular level," Dr. Limsui says.

This investigation is part of the Iowa Women's Health Study, which enrolled 41,836 women from Iowa, aged 55-69, in 1986. After exclusions, the study group consisted of 37,285 women. In the
'/>"/>

Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Female hormone cycle affects knee joints
2. IROs Help Determine Medical Necessity of Growth Hormone Therapy
3. A potential new target for treatment of hormone refractory prostate cancer
4. Male Hormone Treatment Provider Announces Family Doctor Alert
5. Autism linked with stress hormone levels
6. Organic Left Standing as the Gold Standard for Consumers Looking to Avoid Food Produced With Synthetic Growth Hormones
7. Hormone Reduces Mortality in Heart Patients With High BP
8. Diplomat Specialty Pharmacy Expands National Growth Hormone Patient Care Program - Hires Denise Piro, RN, BSN
9. Hormone Might Help Restore Female Fertility
10. March 2009 Mayo Clinic Womens HealthSource Highlights Molecular Breast Imaging, Canes and Walkers, Training for an Event and Hormone Therapy for Women
11. Male Hormone Replacement Company Renewman.com Critical of MLB for Testosterone Abuse Publicity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2015)... Colorado spine surgeon Donald Corenman, MD, ... popular spine education website NECKANDBACK.COM and his ... Media. This website has been redesigned to help patients ... spine, causes of neck and back pain, and conditions ... and personally answers questions in the neck and back ...
(Date:4/28/2015)... The buyer power score for ... indicating a medium level of buyer power in the ... equal power during negotiations. One factor helping buyer power ... health insurance policy from an insurance carrier (such as ... choose to self-fund their own policy or forgo insurance ...
(Date:4/28/2015)... It’s not all about the law at the Law ... litigation and plaintiff’s personal injury lawyer that has also served ... also about giving back to the community. This is ... Research Center Innovator’s Network. , “I believe there is a ... can and do good community-focused work in their communities,” said ...
(Date:4/28/2015)... SeniorCare.com has published the Misconception ... problem Americans have regarding aging and long-term care needs. ... services as they age, 63% of Americans do NOT ... the report, Carol Marak of SeniorCare.com interviewed 44 senior ... Care Association and The Scan Foundation. The experts discuss ...
(Date:4/28/2015)... Dead or damaged trees can quickly turn into ... cases, tree removal by a skilled team is recommended as ... , In their latest article , Precision Tree ... property owners today. Each method requires skill and expertise that ... , The article states that, “Tree removal is not “one ...
Breaking Medicine News(10 mins):Health News:Colorado Spine Surgeon Donald Corenman, MD, DC Launches Updated Version of NECKANDBACK.COM and Popular Back Pain Forum ASKSPINEDOC.COM 2Health News:Colorado Spine Surgeon Donald Corenman, MD, DC Launches Updated Version of NECKANDBACK.COM and Popular Back Pain Forum ASKSPINEDOC.COM 3Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 2Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 3Health News:New Data for Group Health Insurance Procurement Category Market Research Report from IBISWorld 4Health News:Seattle Attorney Paul Schneiderman Helping to Combat Cancer 2Health News:SeniorCare.com Report: America Has a Major Misconception on Aging 2Health News:Tree Removal Methods and Services Discussed in Recent Article by Precision Tree Services 2
... Jan. 28 Prime Companies, Inc. (Pink Sheets: PCIR) ... that will allow it to spin off its wholly ... 2007, to a San Diego firm which, once it ... 15 percent of the new company.The agreement with TransPacific ...
... Essential Hospital Guide to Get Your Loved One Out Alive," by ... Health Book of the Year by Allbooks Review Editor,s Choice Awards ... ... 2009 -- "Critical Conditions: The Essential Hospital Guide to Get Your ...
... of Health Strategies & Solutions, Inc the largest healthcare consultant in ... her expertise in management, governance, finance, operations and medical staff. ... ... The nation,s leading healthcare consulting firm, Health Strategies & ...
... A University of Rochester Medical Center study challenges common assumptions ... some people, surprisingly high levels remain in the body even ... suggests that BPA exposure may come from non-food sources, or ... journal Environmental Health Perspectives published the research online ...
... Jan. 27 Minnesotans with chronic,conditions and disabilities ... under the proposed budget of Gov. Tim Pawlenty, ... Center. , "As a ... thousands of Minnesotans following an illness, surgery or ...
... officials say company distributed ,adulterated, peanut butter products in ... -- The Georgia facility that produced the peanut butter ... in the past distributed questionable peanut butter product, U.S. ... 2008, Peanut Corporation of America, which owns the now-closed ...
Cached Medicine News:Health News:Prime Companies Reaches Agreement to Spin Off Subsidiary; Shareholders Gain 15 Percent Stake in New Telecommunications Company 2Health News:"Critical Conditions" Wins Best Health Book of the Year Awards 2Health News:New Employee of the Nations Largest Healthcare Consulting Firm 2Health News:Rochester study raises new questions about controversial plastics chemical 2Health News:Rochester study raises new questions about controversial plastics chemical 3Health News:Courage Center Experts Disagree With Gov. Pawlenty's Proposed Budget Cuts 2Health News:Courage Center Experts Disagree With Gov. Pawlenty's Proposed Budget Cuts 3Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 2Health News:Salmonella Outbreak Plant Shipped Dubious Product Before: U.S. Health Officials 3
(Date:4/28/2015)... April 28, 2015 Anteo Technologies is ... new tools developed with their patented Mix&Go™ Activation ... methods, helping to improve medical devices and in-vitro ... Increasingly complex multifactorial diagnosis of cancer and ... It is restricted to measure only a ...
(Date:4/28/2015)... TEL AVIV, Israel , April 28, 2015 ... Energy is in its sixth funding cycle for U.S.- ... Renewable Energy and Energy Efficiency. To be considered, ... or cooperation between a company and a university/research institution (one ... ). The proposal should have significant commercial potential and the ...
(Date:4/28/2015)... 28, 2015 We are living a connected life ... the world and very soon we will be able to ... The connected life market has been valued by Frost & ... prepared to drive and manage this change to stay ahead ... Highlights of the congress include a groundbreaking keynote ...
Breaking Medicine Technology:Faster Detection of Disease: Anteo is Transforming The Way Scientists Work with Luminex(R) xMAP(R) 2Faster Detection of Disease: Anteo is Transforming The Way Scientists Work with Luminex(R) xMAP(R) 3Opportunities for Funding U.S.-Israel Cooperation for Renewable Energy and Efficiency 2Frost & Sullivan's GIL 2015 Unveils the $700 Billion Connected Life Market 2Frost & Sullivan's GIL 2015 Unveils the $700 Billion Connected Life Market 3
... most comprehensive family of lightweight standard ... incision, Glaucoma filtration, and Vitreoretinal uses. ... with minimal tissue trauma and minimal ... are available in 18, 20, and ...
... offers the most comprehensive family of ... for Cataract incision, Glaucoma filtration, and ... is achieved with minimal tissue trauma ... eraser styles are available in 18, ...
... most comprehensive family of lightweight standard ... incision, Glaucoma filtration, and Vitreoretinal uses. ... with minimal tissue trauma and minimal ... are available in 18, 20, and ...
... Medtronic Ophthalmics offers the most ... specialty Eraser Instruments for Cataract incision, ... and discrete coagulation is achieved with ... cellular necrosis. Straight eraser styles are ...
Medicine Products: