Navigation Links
Hormone therapy offers potential protective effect against colon cancer in older women
Date:4/22/2009

DENVER In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear.

The study, being presented at the AACR 100th Annual Meeting 2009, was designed to look at possible links between estrogen exposure and colon cancer molecular subtypes, to determine how these hormones might function as anti-cancer agents.

"In our large, prospective study, use of hormone therapy seemed to be beneficial with respect to reducing colorectal cancer risk women who did use these drugs had a 28 percent lower incidence rate than women who did not use these drugs," says the study's lead author, David Limsui, M.D., a fellow in the Department of Gastroenterology at Mayo Clinic's campus in Rochester, Minn. "But we still don't know how estrogen compounds work in cancer prevention, which is intriguing."

Women who reported using other hormone preparations, such as oral contraceptives, did not appear to derive any colorectal cancer prevention benefits. "Based on our findings, we need to continue exploring the cancer pathways that might be affected by these hormones," Dr. Limsui says.

He adds that other studies have also found that hormone therapy protects postmenopausal women against colon cancer. The largest randomized clinical trial was the 16,000-participant Women's Health Initiative, which concluded in 2004 that combination hormone therapy (estrogen and progestin) reduced a woman's risk of colorectal cancer by about 40 percent, he says. "But few studies have delved deeper to see how these hormones work at the molecular level," Dr. Limsui says.

This investigation is part of the Iowa Women's Health Study, which enrolled 41,836 women from Iowa, aged 55-69, in 1986. After exclusions, the study group consisted of 37,285 women. In the
'/>"/>

Contact: Karl Oestreich
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Female hormone cycle affects knee joints
2. IROs Help Determine Medical Necessity of Growth Hormone Therapy
3. A potential new target for treatment of hormone refractory prostate cancer
4. Male Hormone Treatment Provider Announces Family Doctor Alert
5. Autism linked with stress hormone levels
6. Organic Left Standing as the Gold Standard for Consumers Looking to Avoid Food Produced With Synthetic Growth Hormones
7. Hormone Reduces Mortality in Heart Patients With High BP
8. Diplomat Specialty Pharmacy Expands National Growth Hormone Patient Care Program - Hires Denise Piro, RN, BSN
9. Hormone Might Help Restore Female Fertility
10. March 2009 Mayo Clinic Womens HealthSource Highlights Molecular Breast Imaging, Canes and Walkers, Training for an Event and Hormone Therapy for Women
11. Male Hormone Replacement Company Renewman.com Critical of MLB for Testosterone Abuse Publicity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/3/2015)... ... July 03, 2015 , ... ... sessions and speaker lineup for its 2015 Annual Conference , the ... 6-8, 2015 at the Renaissance Orlando at SeaWorld in Orlando, Florida. Speakers ...
(Date:7/3/2015)... ... July 03, 2015 , ... B. E. Smith, the only ... lead a national president recruitment for Regional Care, Inc. in Scottsbluff, ... E. Smith has recently placed more than 1,000 healthcare executives into organizations. ...
(Date:7/3/2015)... ... July 03, 2015 , ... Smoothies are all the rage right now ... easily accessible, quality ingredients. Aurora Natural is proud to introduce a new line of ... fiber, protein, antioxidants, vitamins and minerals! , Aurora is offering a variety of blends ...
(Date:7/3/2015)... ... , ... First Choice Emergency Room , the largest network of independent ... new Medical Director of its Frisco facility. , “We are pleased to announce that ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:7/3/2015)... (PRWEB) , ... July 03, 2015 , ... Every year, ... 24-Hour Train-a-Thon where they provide members of the Red Deer community with free fitness ... day of fitness training, games, food, events and entertainment raised thousands of charity dollars ...
Breaking Medicine News(10 mins):Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3Health News:Aurora Product, Inc. Announces An Original New Line: Smoothie Fixins’ 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 2Health News:First Choice Emergency Room Announces Dr. Mariah N. Manzanares as Medical Director of Frisco, TX Facility 3Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 2Health News:Red Deer Fitness Studio Raises $10,000 for Charity Organization with 24-Hour Train-a-Thon 3
... 4 Americans has,diabetes or is at risk for developing ... The following,release was issued today by the American Diabetes ... American Diabetes Month(R),brings to light the fastest growing health ... Americans have diabetes or are at risk of,developing type ...
... It,s linked to obesity, which then triggers hypertension, study ... kids who develop hypertension may be watching far too ... "illustrates the need for considerable physician and family involvement ... Dr. Jeffrey B. Schwimmer, associate professor of pediatrics at ...
... /PRNewswire-FirstCall/ - Labopharm Inc. (TSX: DDS;,NASDAQ: DDSS) today ... the Company, will present at the CIBC World ... on Monday, November 5, 2007 at 3:40,p.m. ET. ... for this presentation by,visiting the "Events" section of ...
... 150+ Nursing Homes in California will simultaneously open their ... media are invited to cover the,festivities, INLAND EMPIRE, ... gypsies visit a nursing home. Nurse administrators,don,t often see ... to meet 90-year-old soldiers or 80-year-young,ballerinas! But at more ...
... 150+ Nursing Homes in California will simultaneously open their ... invited to cover the,festivities, EUREKA, Calif., Oct. 30 ... nursing home. Nurse administrators don,t often,see miniature witches and ... 90-year-old soldiers or 80-year-young ballerinas! But at more,than 150 ...
... Texas, Oct. 30 ULURU Inc. (Amex:,ULU) announced ... a voluntary,Odd-Lot Buy Back Offer, whereby the Company ... less than 100 shares of common stock. This,program ... with,stockholder recordkeeping and communications costs and the potential ...
Cached Medicine News:Health News:American Diabetes Month(R) Brings Awareness to Growing Health Care Crisis 2Health News:Too Much TV Can Raise Kids' Blood Pressure 2Health News:Labopharm to present at CIBC World Markets 18th Annual Healthcare Conference 2Health News:Halloween Events in Southern California Bring Young and Old Together for a Ghoulish Good Time 2Health News:Halloween Events in Eureka, California Bring Young and Old Together for a Ghoulish Good Time 2Health News:ULURU Inc. Announces Odd-Lot Buy Back Offer 2
(Date:7/3/2015)... HUATULCO, Mexico , July 3, 2015 ... targeting the epidemics of hypertension, diabetes and thyroid disorders ... online educational platforms and a major conference dedicated to ... Manage Diabetes Online , Manage Hypertension ... each developed and operated by EXCEMED - ...
(Date:7/3/2015)... -- Redwood Pharma AB has entered into ... in both the US and China ... supramolecular hydrogel technology in its lead chronic Dry Eye ... Broda technology offers many unique competitive benefits. At lower ... with low concentrations of polymer the system can be ...
(Date:7/2/2015)... July 2, 2015 Leading organizations have ... critical product and market insights in internal market ... employee-based studies, it is essential for executives to ... employees to capture critical business-related insights. ... Best Practices, LLC, most benchmarked companies find it ...
Breaking Medicine Technology:Combating Three Major Chronic Diseases in Latin America With Medical Education 2Redwood Pharma Licenses Novel Hydrogel Drug Delivery Technology From Broda Technologies 2Leveraging Employee Insights to Produce Cutting-Edge Market Research 2
... Calif., Oct. 8 Endologix, Inc. (Nasdaq: ELGX ), ... that it has become aware that Cook Medical has filed ... alleging that Endologix infringes two of Cook,s U.S. patents. , ... have just become aware of the lawsuit filed by Cook ...
... PHILADELPHIA, Oct. 8 GlaxoSmithKline (NYSE: GSK ) today ... Patent and Trademark Office (USPTO) to join the USPTO,s motion ... 2007 (Triantafyllos Tafas and SmithKline Beecham Corporation, SmithKline Beecham PLC ... United States Patent and Trademark Office). GSK and the ...
Cached Medicine Technology:Endologix Comments on Alleged Patent Infringement 2GlaxoSmithKline and U.S. Patent and Trademark Office File a Motion to Dismiss Litigation Over Final Regulations 2
The uncemented hip joint prosthesis system...
The proximally modular S-ROM Total Hip System provides custom capability at non-custom prices and is competitive with conventional porous coated systems....
The Natural-Hip combines the surgical simplicity of a straight stem with many of the best features of an anatomic stem....
The Natural-Hip combines the surgical simplicity of a straight stem with many of the best features of an anatomic stem....
Medicine Products: