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Heavy drinking, conduct disorder linked to high-risk sexual behavior

St. Louis, Dec. 3, 2007 Psychiatry researchers at Washington University School of Medicine in St. Louis have found that a clinical diagnosis of alcohol dependence in young adults is associated with having a high number of sex partners.

"Some participants in the study reported 50 or 100 partners, and research shows and common sense tells you that the more sex partners you have, the more likely you'll encounter someone with an STD," says first author Patricia Cavazos-Rehg, Ph.D., research instructor in the Department of Psychiatry. "Chances also increase for unintended pregnancies and other health complications."

The study, published in the December issue of the journal Alcoholism: Clinical & Experimental Research, also found links between a conduct disorder diagnosis and high numbers of sexual partners as well as between problem drinking and more partners. Of the three, however, alcohol dependence had the most influence on number of sex partners.

Alcohol dependence is an excessive use of alcohol that's harmful to physical and mental health. Some alcohol-dependent people drink every day. Others may drink only sporadically but consume large amounts of alcohol when they do drink. That sort of binge drinking is particularly common in adolescents and young adults, like those surveyed in this study. Problem drinkers, on the other hand, have many of the same symptoms, and may go on to become dependent, but they were not alcohol dependent when the study was conducted.

Conduct disorder is a disruptive disorder, like ADHD or oppositional defiant disorder. Its symptoms tend to include truancy from school, setting fires, getting into fights or being cruel to people or animals.

Of those in this study who were alcohol dependent, 45 percent reported having 10 or more sexual partners. In addition, 37 percent of those with a conduct disorder diagnosis had at least 10 partners.

Previous studies have linked heavy drinking and conduct disorder to high-risk sexual behavior. This study focused specifically on the number of partners, and it defines high risk using a larger number than typically seen in the psychiatric literature.

"To my knowledge, most research in young adults has used a standard of 'up to six' sex partners when examining risk," Cavazos-Rehg says. "But the average number of partners for the people in this study was 9.26, so instead of using 'six or more' partners as our standard for high risk, we increased that number to 10."

The researchers conducted personal interviews with 601 people between 18 and 25 years old. All were unmarried and related to alcohol-dependent individuals who participated in the national Collaborative Study on the Genetics of Alcoholism (COGA), an ongoing project involving interviews and DNA samples from more than 10,000 people. The COGA database includes individuals from inpatient and outpatient alcohol treatment centers and their families. Families in the COGA study usually have multiple members with alcohol dependence.

"We categorized these subjects according to three levels of alcohol involvement non-dependent, problem drinking and alcohol dependent and demonstrated how a stepwise increase from non-dependence to problematic alcohol use to alcohol dependence is associated with a higher number of sexual partners," says Cavazos-Rehg. "We found that 22 percent of the non-dependent people had 10 or more partners, compared to 31 percent of problem drinkers and 45 percent of those who were alcohol dependent. We also found a risk for a high number of sexual partners among those with conduct disorder, independent of their level of alcohol involvement. And those with both alcohol dependence and conduct disorder were at greatest risk of having a high number of sex partners."

Cavazos-Rehg suggests when young people are treated for alcohol problems from inpatient treatment for alcohol dependence to emergency care following an alcohol-related car accident it might be a good idea to screen them for STDs or HIV infection and to discuss safe sex practices. Personnel at STD clinics also might want to ask patients about their alcohol use and provide referrals to alcohol-related treatment centers.

"Perhaps clinicians can work together to treat both problems," she says. "A better understanding of alcohol dependence and conduct disorder could become part of a comprehensive strategy for reducing the transmission of STDs and unintended pregnancies."


Contact: Jim Dryden
Washington University School of Medicine

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