Navigation Links
Heart failure risk model validated
Date:3/30/2009

Researchers at Emory University School of Medicine created the Health ABC Heart Failure Model for predicting risk of new onset heart failure in the elderly. Now that model has been strengthened by validating it in a separate library of patient data from an earlier cardiovascular study.

The results suggest the Health ABC risk model can be used to identify high-risk individuals for whom interventions can be targeted cost-effectively to prevent heart failure.

"This is a scoring system that could help individuals or their physicians understand their five-year risk for heart failure, using basic risk factors that are easily obtained at relatively low cost," says Javed Butler, MD, MPH, associate professor of medicine and director of heart failure research at Emory University School of Medicine.

Andreas Kalogeropoulos, MD, a post-doctoral research fellow with Butler, presents the findings Monday at the American College of Cardiology conference in Orlando.

Heart failure is the leading cause of hospitalization in people older than 65 and greatly increases the risk of sudden cardiac arrest.

The Health ABC model uses nine clinical measures to estimate the risk of heart failure in patients who haven't necessarily been seen by doctors for coronary heart disease before. The nine measures are: age, history of coronary heart disease, smoking, blood pressure, heart rate, left ventricular hypertrophy measured by electrocardiography, and blood levels of glucose, creatinine and albumin.

Several individual risk factors for heart failure have been identified, but Butler says the model is the first that combines the risk factors into a system for predicting risk for any given individual. The model categorizes individuals into four risk categories ranging from less than 5 (low) to more than 20 percent (very high) 5-year risk, and has been shown to perform well for men, women, Caucasians and African Americans.

"Considering the high cost of care and poor outcomes for patients who develop heart failure, any effort to identify these individuals early on and facilitate intervention is likely to be of significant benefit," Butler says.

The Health ABC model grew out of the Health Aging and Body Composition Study, which followed 2,935 elderly people in the Pittsburgh and Memphis areas over seven years starting in 1998. The model was validated by assessing it in 5,335 people without pre-existing heart failure from North Carolina, California, Maryland and Pennsylvania who were participants in the Cardiovascular Health Study beginning in 1989.

Butler and his colleagues also are presenting data from the Health ABC study confirming previous work elsewhere showing that blood glucose can predict heart failure risk even in non-diabetics and evaluating the additional information doctors can glean from different measures of blood pressure.

Reference for the Health ABC heart failure risk model: Circulation Heart Failure 2008,1:125-133


'/>"/>

Contact: Sarah Goodwin
sgoodwi@emory.edu
404-727-3366
Emory University
Source:Eurekalert

Related medicine news :

1. Drug for cluster headaches may cause heart problems
2. Use of certain lipid measures not more effective in predicting coronary heart disease
3. Restricting Blood Flow May Help Heart Bypass Patients
4. Urban Smog Tough on Young Adults Hearts
5. Stanford study highlights cost-effective method of lowering heart disease risks
6. Vitamin Es lack of heart benefit linked to dosage
7. Drug That Lowers Resting Heart Rate Being Tested
8. Heart Attack Boosts Diabetes Risk
9. Embryonic Stem Cells Repair Human Heart
10. U of M study: Early treatment can reverse heart damage
11. Embryonic Human Stem Cells May Help Repair Heart Muscle, Lab Study Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Aliso Viejo, California (PRWEB) , ... June 25, 2016 , ... ... preset to fit their specific project," said Christina Austin - CEO of Pixel Film ... all fully customizable and all within Final Cut Pro X . Simply select ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from PsychTests.com reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing skills ... patients and their families pay tribute to a genetic counselor by nominating him or ... Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome magazine ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone ... executive with extensive sequencing and genomics experience, as Vice President of North American Capital ... will be responsible for leading the sales team in the commercialization of the HTG ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
(Date:6/23/2016)... Ill. , June 23, 2016  In a startling report ... are failing their residents by lacking a comprehensive, proven plan to ... a definitive ranking of how states are tackling the worst ... to only four states – Kentucky , ... Vermont . Of the 28 failing states, three ...
Breaking Medicine Technology: