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Hallucinogen appears safe, may improve mood among patients with advanced-stage cancer and anxiety
Date:9/6/2010

re administered before and at the end of the session, one day and two weeks after the session and at monthly intervals for the following six months.

"Safe physiological and psychological responses were documented during treatment sessions," the authors write. "We also observed no adverse psychological effects from the treatment. All subjects tolerated the treatment sessions well, with no indication of severe anxiety or a 'bad trip.'" In addition, anxiety scores improved at one and three months after treatment and a depression inventory revealed an improvement of mood that began two weeks after treatment and reached significance at six months.

"This study established the feasibility and safety of administering moderate doses of psilocybin to patients with advanced-stage cancer and anxiety," the authors conclude. "Some of the data revealed a positive trend toward improved mood and anxiety. These results support the need for more research in this long-neglected field."


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Contact: Laura Mecoy
Lmecoy@issuesmanagement.com
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JAMA and Archives Journals
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