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Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com
Date:7/13/2014

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Graft-versus-host disease (GVHD) is a common complication of allogeneic hematopoietic stem cell transplantation (HSCT) that occurs when the donated (graft) cells are rejected and attack the host’s cells as foreign. GVHD can progress from mild to severe forms as either acute GVHD (aGVHD) or chronic GVHD (cGVHD). Both aGVHD and cGVHD commonly affect organs such as the skin, gastrointestinal (GI) tract, liver, oral mucosa, and eyes (Hymes et al., 2012). The global distribution of GVHD is directly dependent on transplantation-related factors, including the donor type, the age of the donor and the recipient, the sex parity between the recipient and the donor, the pre-transplantation conditioning regimen, and the use of GVHD prophylaxis pre- and/or post-transplantation. Around 30–70% of HSCT recipients will develop aGVHD, and another 30–70% will develop cGVHD independent of aGVHD (Arora et al., 2011; Champlin et al., 2000; Hymes et al., 2012; Jagasia et al., 2012; Joseph et al., 2008; Przepiorka et al., 1999). GVHD can be unpleasant and reduces the quality of life following HSCT, and in severe forms, significantly increases the risk of non-relapse mortality (Hymes et al., 2012; Wood et al., 2013). The number of persons with GVHD will continue to increase with the increase in survival of patients with GVHD and the increase in the number of patients who are at risk of developing aGVHD and cGVHD due to the increase in the number of allogeneic HSCTs performed worldwide (Joseph et al., 2008; Lee et al., 2003; Wood et al., 2013).

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This report provides an overview of the risk factors, comorbidities, and the
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