Navigation Links
Gauging Brain Cancer Survival Time May Get Easier: Study
Date:4/10/2013

WEDNESDAY, April 10 (HealthDay News) -- Life expectancy of people with aggressive brain cancer may be easier to determine with a new method under development at the University of Alabama at Birmingham, researchers say.

The UAB researchers found that patients with an overactive version of a specific enzyme live less than half as long as those with a less active version. This overactive enzyme can help predict how resistant the brain cancer will be to chemotherapy, and also help doctors arrive at treatment recommendations, the researchers said.

In conducting the study, published April 10 in the journal PLoS ONE, the researchers examined tumors from 84 patients with a form of brain cancer known as glioblastoma multiforme (GBM). This deadly and aggressive cancer quickly becomes resistant to available treatments. With a combination of surgery, radiation and the chemotherapy drug temozolomide, patients with this form of brain cancer typically survive an average of 12 to 15 months.

The study revealed, however, that 25 percent to 30 percent of the patients whose tumor cells had an overactive version of an enzyme known as cytochrome c oxidase (CcO) live less than half as long as patients with a less active version.

"Our study reports for the first time the role of [CcO] as a prognostic marker in GBM patients' tumor tissues," study leader Corinne Griguer, an associate professor of neurosurgery in the UAB School of Medicine, said in a university news release. "High CcO activity comes with a 25-fold increase in risk of death."

The researchers said patients with the overactive enzyme lived for an average of six months. Those with a less active version lived for 14 months. Examination of a second group of glioblastoma multiforme patients from Europe confirmed their findings, the researchers said.

They concluded that tumor cells with increased CcO activity generate more energy and are more resistant to ch
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Gauging seizures severity
2. For First Time, Pain Signature Spotted on Brain MRIs
3. Brain Surgery Eases Compulsive Eating in 10-Year-Old Girl
4. A New Peer-Reviewed Study Using CogniFit Brain Training Provides A Breakthrough In The Treatment Of Insomnia
5. RI Hospital: Traumatic brain injury worsens outcomes for those with nonepileptic seizures
6. Extracellular vesicles may open new opportunities for brain cancer diagnosis and treatment
7. Non-invasive mapping helps to localize language centers before brain surgery
8. Scans May Reveal Pre-Schizophrenia Brain Changes
9. Sexuality, traumatic brain injury, and rehabilitation
10. New minimally invasive, MRI-guided laser treatment for brain tumor found to be promising in study
11. Voices Against Brain Cancer Responds to Research Identifying Contributing Factor in Brain Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gauging Brain Cancer Survival Time May Get Easier: Study
(Date:9/1/2015)... ... September 01, 2015 , ... OncLive® ... by U.S. News & World Report, to provide breaking news and information about ... marketing groups within OncLive, which provides oncologists resources and information?they need to deliver ...
(Date:9/1/2015)... ... , ... The Jerry Segal Classic to benefit the patients of Magee Rehabilitation ... in Lafayette Hill, PA. Over the past 26 years, the Classic, organized by the ... designed to support patients and their families during their time at Magee Rehabilitation Hospital. ...
(Date:9/1/2015)... ... 2015 , ... With former IBMers among its founding members, Inmar has known ... than 35 years ago. A pilot program begun by the company in 2014 has ... those intent on pursuing careers in these fields. The program is now open to ...
(Date:9/1/2015)... ... September 01, 2015 , ... e-Spirit Inc., a ... of the FirstSpirit Content Management System with new capabilities and enhancements designed to ... FirstSpirit, companies will be well on their way to achieving digital transformation with ...
(Date:9/1/2015)... York, New York (PRWEB) , ... September 01, 2015 , ... ... Zecurion Zlock Mac , its groundbreaking new version of endpoint DLP developed specifically ... of Zlock Mac, in which more than 100 IT and information security professionals had ...
Breaking Medicine News(10 mins):Health News:OncLive® and Cleveland Clinic Team up to Provide News, Information About Cancer Research and Patient Care 2Health News:OncLive® and Cleveland Clinic Team up to Provide News, Information About Cancer Research and Patient Care 3Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 2Health News:The 26th Jerry Segal Classic Returns to Benefit Patients of Magee Rehabilitation Hospital 3Health News:Inmar Announces Program to Fuel Student Passion for STEM – with an Unconventional Twist 2Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 2Health News:e-Spirit boosts Corporate Content Cloud initiative with release of FirstSpirit 5.2 3Health News:Zecurion Announces Endpoint Security for Mac 2
... study has come out strongly against the use of sunbeds ... ,According to the Working Group on artificial UV ... on Cancer (IARC), persons who use these tanning beds in ... exposing themselves to higher risks of developing melanoma, the most ...
... in Maine criticized the anti-fluoride campaigns made by a Bangor ... the false information and alter their water treatment policies. ... Disease Control had confirmed in a news conference that public ... fighting tooth decay. ,This announcement has come ...
... on time is crucial to provide quality care to ... discovered// that nearly 10% of scan results never reach ... for the year 2005/2006. ,Worse still, the ... be overlooked; in some cases a tacit agreement between ...
... acute respiratory syndrome (SARS) epidemic in China has lessons ... of other respiratory diseases// , according to new research ... Diseases, currently available online. ,Hospitals were epicenters ... in 2003. In hospitals with especially severe outbreaks, the ...
... technique called applied relaxation training (ART); however, a recent ... - an age old technique employed since the 20th ... ,During the study, 49 patients were given psychotherapy twice ... The training helped patients pick up ways to relax ...
... inspiration of most new drugs created in the last quarter century, ... the natural// products branch of the National Cancer Institute (NCI) of ... approved from January 1981 through June 2006 for all diseases worldwide. ... conditions. ,Only thirty percent of the new drugs were ...
Cached Medicine News:Health News:Study Identifies Risk Factors for Spread of Respiratory Infections in Hospitals 2
(Date:9/1/2015)... 1, 2015  Valeant Pharmaceuticals International, Inc. (NYSE: ... that its affiliate has entered into a collaboration ... an exclusive license to develop and commercialize brodalumab. ... monoclonal antibody in development for patients with moderate-to-severe ... Valeant will hold the exclusive rights to develop ...
(Date:8/31/2015)... 2015  Chiasma, Inc. (NASDAQ: CHMA ), ... for the orphan condition acromegaly, today reported financial ... 2015 and provided a corporate update. ... time for Chiasma, as we successfully completed our ... first New Drug Application (NDA) has been accepted ...
(Date:8/31/2015)... VIEW, Calif. , Aug. 31, 2015 /PRNewswire/ ... for flow cytometry is experiencing a rise in ... the demand in underdeveloped nations to quantitate CD4 ... Logo - http://photos.prnewswire.com/prnh/20150831/262206LOGO ... Analysis of the Global Flow Cytometry Market ( ...
Breaking Medicine Technology:Valeant And AstraZeneca To Partner On Brodalumab 2Valeant And AstraZeneca To Partner On Brodalumab 3Valeant And AstraZeneca To Partner On Brodalumab 4Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 2Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 3Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 4Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 5Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 6Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 7Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 8Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 9Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 2Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 3Clinical Applications of Flow Cytometry Instrumentation and Reagents are Transforming this Market with a High-Growth Path 4
... Access Communications, LLC (Access) has named David P. Gagliano the ... the leadership of a group of managing partners, a role in which ... , , , ... and honored to be named president and CEO of Access," said Gagliano. ...
... June 15 DATATRAK International, Inc. (OTCQX: DATA), ... for the clinical trials industry, premiered the release of its ... DATATRAK Safety Case Manager ™ collects individual case safety ... XML format for transmission to regulatory authorities. The Safety ...
Cached Medicine Technology:New President and Chief Executive Officer Named at Access Communications, LLC 2New President and Chief Executive Officer Named at Access Communications, LLC 3DATATRAK Premieres Safety System at DIA 2DATATRAK Premieres Safety System at DIA 3
... Units,Filter units with hydrophobic PTFE membranes,Millex ... are ideal for the sterilizing filtration ... containers, and for sterilizing or clarifying ... Millex filter units are available with ...
... Millex Filter Units,Filter units with ... hydrophobic Fluoropore membrane are ideal for ... venting of sterile containers, and for ... sterile 25 mm Millex filter units ...
... Bottled Water, The Simplicity personal water system ... currently use bottled water. In addition to ... store bottled water, your laboratory applications may ... be absorbed from containers and cause water ...
Designed to meet the requirements of reagent grade water for routine analysis....
Medicine Products: