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From genomic data to new cancer drug
Date:10/27/2011

When the researchers injected EPHA7 into mice with human tumors, those tumors shrunk. They found that a particularly effective way to deliver EPHA7 to cancer cells is to fuse it with an antibody that specifically targets lymphomas.

The researchers say EPHA7 has immediate therapeutic potential, although they intend to pursue smaller versions of the protein that might be easier to make. There is also reason to think EPHA7 may ultimately have promise for the treatment of other forms of cancer as it binds a protein with links to breast and ovarian cancer.


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Contact: Elisabeth (Lisa) Lyons
elyons@cell.com
617-386-2121
Cell Press
Source:Eurekalert

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