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Flies model a potential sweet treatment for Parkinson's disease
Date:4/6/2013

g it as a BBB disruptor to facilitate entrance of other approved drugs that have problems passing through the BBB," Dr. Segal said. A preliminary clinical trial of mannitol on a small number of volunteers might follow if results in mice support those seen in the flies, he added, but that is still many research steps away.

Session Title: Drosophila Models of Human Diseases I
Program #91 -- Date and Time: Saturday, April 6, 2013; 8:30-8:45 AM
Location: Marriott Wardman Park, Marriott Ballroom Salon 1, Lobby Level
Mannitol -- a BBB disrupter is also a potent α-synuclein aggregation inhibitro for treating Parkinson's disease. Daniel Segal1,2, Ronit Shaltiel-Karyo1, Moran Frenkel-Pinter1, Edward Rockenstein3, Christina Patrick3, Michal Levy-Sakin1, Nirit Egoz-Matia1, Eliezer Masliah3, Ehud Gazit1. 1) Department of Molecular Microbiol & Biotech, Tel Aviv University, Tel Aviv 69978, Israel; 2) Sagol School of Neurosciences, Tel Aviv University, Tel Aviv 69978, Israel; 3) Department of Neurosciences, School of Medicine, University of California at San Diego, La Jolla, CA 92093, USA.


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Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-634-7302
Genetics Society of America
Source:Eurekalert

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