Navigation Links
Faulty DNA repair could be a risk factor for lung cancer in nonsmokers
Date:6/26/2008

air capacity as a risk factor for lung cancer in nonsmokers. Researchers drew white blood cells from 219 lung cancer patients and 309 matched control participants, all of whom had never smoked. They used the cells to conduct a host-cell reactivation assay, a complicated test that introduced a specific carcinogen, benzo[a]pyrene diol epoxide (BPDE) into the cells. BPDE is a hydrocarbon found in smoke of all kinds (tobacco, wood, etc.) that is highly carcinogenic and mutagenic, capable of changing the composition of DNA.

The study is a continuation of research underway at M. D. Anderson that is looking for genetic and epigenetic components to lung cancer risk. The research group has previously shown that DNA repair capacity as measured by the host cell reactivation assay was significantly lower in lung cancer patients who were current or former smokers than in matched controls.

"Many people think they aren't at risk for lung cancer because they don't smoke, but anyone who has non-smoking relatives with lung cancer should avoid not just tobacco smoke, but all the other carcinogens and mutagens that are products of combustion," Gorlova said.


'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Faulty brain connections may be responsible for social impairments in autism
2. St. Jude Finds Mechanism for Faulty Protein Disposal
3. St. Jude finds mechanism for faulty protein disposal
4. Pedophilia may be the result of faulty brain wiring
5. Evalve MitraClip: Clinical trial of nonsurgical repair for severe mitral valve regurgitation
6. 2nd Option Improves Abdominal Aorta Repair Outcomes
7. Joint distraction promotes structural repair in patients with severe knee osteoarthritis
8. Industrial Control Repair Named Honda of America Manufacturings 2007 Supplier of the Year
9. Finding clues for nerve cell repair
10. New stem cell therapy may aid the repair of damaged brains
11. Collaborative Drug Discovery and Myelin Repair Foundation Announce Partnership
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... Dealing with a drug or alcohol substance abuse is never ... child. Adolescent addiction has been an important issue among young ... helpline is now providing a valuable resource for teenage ... addiction recovery center. , The Troubled Teens Atlanta helpline was ... By calling (404) 975-2762, parents and their teens can speak ...
(Date:8/23/2014)... 23, 2014 Teen drug and alcohol ... no different in Wilmington, NC. Substance abuse can happen ... victim to drug and alcohol dependency in higher numbers ... to overcome substance abuse, but don’t know where to ... facility can be a challenge because most treatment options ...
(Date:8/23/2014)... Summer vacation is almost over and before we know it ... for school supplies and a new wardrobe might take precedence ... to also spend some time brushing up on bed bug ... in heavily populated places,” said Randy Rupert, Bed Bug Team ... settings for bed bugs to take up residence.” , An ...
(Date:8/22/2014)... 23, 2014 The IT manager of ... hosting for several years. He has recently announced that ... hosting suppliers in 2014. , GoDaddy is a popular ... features and great hosting solutions at affordable rates. It ... for shared hosting plans depend on the length of ...
(Date:8/22/2014)... On Friday, Aug. 22, Liberty University unveiled its ... hosting a ceremony in its courtyard attended by some ... welfare. , The 162-member inaugural class of the ... Liberty staff, faculty, and community leaders in celebrating the ... school. Classes began on Monday, Aug. 4. , The ...
Breaking Medicine News(10 mins):Health News:Atlanta’s New Troubled Teen Helpline Is Making a Difference in the Community 2Health News:Troubled Teens Wilmington Helpline Guides Adolescents to the Path of Recovery 2Health News:Expert Advice for a Bed Bug-Free School Year 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 3Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 4
... for the ongoing World Championships seem to be too keen ... //of rupturing their womb muscles that could prevent them from ... others, mostly foreign boxers, marriage is not on their radar ... Mary Kom, 24, who is seeking a third successive gold ...
... eggs with red yolk are considered to be more nutritious ... eggs are natural – says a recent investigations. ... investigation that found that the red color found in many ... as Sudan Red I, a toxic industrial colorant, being used ...
... The Pediatric Dengue Vaccine Initiative (PDVI), a program of ... , announced today their partnership to help develop and ... prevention of Dengue fever, the second most widespread tropical ... disease to which over 2 billion people are exposed ...
... Those in their 50s and 60s who want to ... room instead of counting calories, suggests new research out ... and those who exercised lost a significant amount of ... whether a calorie-restriction diet can extend lifespan. However, while ...
... the immune systems in colorectal cancer patients to attack ... of 67 patients, researchers at the University of Nottingham ... post surgery of the cancerous growth, it activated the ... The November 15 issue of Clinical Cancer Research has ...
... works as well as some sports drinks like Gatorade. The ... conducted by Indiana University // suggested found that those ... longer than those drinking a carbohydrate drink, an effect similar ... ,The story was picked up as mainstream news in many ...
Cached Medicine News:Health News:As these women box on, do they risk becoming mothers? 2Health News:As these women box on, do they risk becoming mothers? 3Health News:Fear Of Cancer Due To Duck Egg Contamination In China 2Health News:Pediatric Dengue Vaccine Initiative and Hawaii Biotech Partner Against Dengue Fever 2Health News:New Study Weighs Benefits of Exercise, Diets 2Health News:A novel vaccine proves a shot in the arm for colorectal cancer patients 2
(Date:8/21/2014)... , Aug. 21, 2014  Vermillion, Inc. (NASDAQ: ... gynecologic cancers and women,s health, has appointed Holly ... Managed Markets. Ms. Bauzon has a proven ... payer coverage for laboratory services companies. She has more ... PerkinElmer, Inc., where she held the position of Director, ...
(Date:8/21/2014)... YORK , Aug. 21, 2014  Publicis Groupe ... Shannon Hartley , Managing Partner and Healthcare Industry Group ... PharmaVoice 100, which recognizes the most inspiring people in ... are leaders in research and development, marketing, technology, creativity, ... agency in 2006 as a partner in its leading ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ... Equipment, Inc. for the third straight year, No. ... 500|5000, an exclusive ranking of the nation,s fastest-growing ... look at the most important segment of the ... Timberland, Dell, Domino,s Pizza, LinkedIn, Zillow, and many ...
Breaking Medicine Technology:Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2Shannon Hartley Shines in PharmaVOICE 100 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3
... Nov. 10, 2011 ADVENTRX Pharmaceuticals, Inc. (NYSE Amex: ... market and other conditions, to offer and sell shares of ... in an underwritten public offering.  The Company also intends to ... an additional 15% of the shares and warrants sold in ...
... Throughout the healthcare industry, compliance guidelines for pharma,s interactions ... tightening as increased regulations intensify scrutiny and budget constraints ... cycles are slowing and more pressure is being placed ... of pharma PTR groups feel compliance concerns will lead ...
Cached Medicine Technology:ADVENTRX Announces Public Offering of Stock 2ADVENTRX Announces Public Offering of Stock 3Restrictive Compliance Environment Weakens Professional and Trade Relations Group Impact 2
Injection Cannula, Angled; 20g (0.90) x 1" (25mm); Tip Extension: 5mm, 30g (0.30); Angled at 45°, 2.5mm from Tip....
...
Lacrimal Cannula, Curved - Open End, 21gSize: 21g x 1-1/2"....
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Medicine Products: