Navigation Links
Facial defects shown to self-repair
Date:4/25/2012

nalyzed to understand the precise dynamics of the corrective process.

"What was missing from previous studies and to our knowledge had never been done in an animal model was to precisely track those changes over time and quantitatively compare them," said first author Laura Vandenberg, Ph.D., post-doctoral associate at the Center for Regenerative and Developmental Biology. Such an analysis is crucial in order to begin to understand what information is being generated and manipulated in order for a complex structure to rearrange and repair itself.

Co-author with Levin and Vandenberg was Dany S. Adams, Ph.D. Adams is a research associate professor in the Department of Biology and a member of the center.

The Tufts biologists induced craniofacial defects in Xenopus frog embryos by injecting specific mRNA into one cell at the two-cell stage of development; this resulted in abnormal structures on one side of the embryos. They then characterized changes in the shape and position of the craniofacial structures, such as jaws, branchial arches, eyes, otic capsules and olfactory pits, through "geometric morphometric analysis," which measured positioning of a total of 32 landmarks on the top and bottom sides of the tadpoles.

Images of tadpoles taken at precise intervals showed that as they aged, the craniofacial abnormalities, or perturbations, became less apparent. This was particularly true for the jaws and branchial arches. Eye and nose tissue became more normal over time but varied in ability to achieve a completely expected shape and position.

Changes in the shape and position of facial features are a normal part of development, as any baby animal shows. With age, faces elongate and eyes, nose and jaws move relative to each other. But the movement is normally slight.

In contrast, the Tufts research team found that in tadpoles with severe malformations, the facial structures shifted dramatically in order
'/>"/>

Contact: Kim Thurler
kim.thurler@tufts.edu
617-627-3175
Tufts University
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Bipolar Kids May Focus on Different Facial Features
2. Can Facial Flaws Cost You the Job?
3. Brain function involved in recovery of facial paralysis is different according to sex
4. Severity of facial wrinkles may predict bone density in early menopause
5. Facial structure of men and women has become more similar over time
6. Eye Surgery May Benefit Some Patients With Facial Paralysis
7. Fuz is essential for craniofacial and tooth development
8. Facial Surgery May Offer Long-Term Migraine Relief for Some
9. Minimally invasive technique appears helpful to reanimate facial paralysis
10. Age Takes Toll on Facial Bones, Study Finds
11. Infants hemodynamic responses to happy and angry facial expressions
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Facial defects shown to self-repair
(Date:8/28/2014)... vaccine to prevent Ebola virus disease will begin next ... Diseases (NIAID), part of the National Institutes of Health. ... of a vaccine co-developed by NIAID and GlaxoSmithKline (GSK) ... to generate an immune system response in healthy adults. ... in Bethesda, Maryland. , The study is the first ...
(Date:8/28/2014)... 70 and over who identify themselves as ,old, feel ... perceive they have lower value than younger age groups. ... Kent, titled ,Being old and ill, across different countries: ... used data from the European Social Survey. Respondents, who ... self-rate their health., The researchers found that those living ...
(Date:8/28/2014)... August 28, 2014 Vaccine market - ... great interest among other healthcare industry sectors and sub-circles ... demand in vaccine with respect to evolving and spreading ... due to an improved understanding for a well-balanced life ... States. It has led to new opportunities for manufacturing ...
(Date:8/28/2014)... TX (PRWEB) August 28, 2014 After ... Dr. Paul Vitenas is excited to announce the ... of its kind in any city, Mirror Mirror Beauty ... building. , Situated on the corner of Richmond and ... modern architecture, luxurious amenities, and cutting-edge technology in a ...
(Date:8/28/2014)... Steven Reinberg HealthDay ... Treating pre-cancerous skin spots with a type of light therapy ... the lesions with liquid nitrogen, a new study suggests. ... the scalp and face of people with fair complexions who,ve ... of prior research found that people who underwent the light ...
Breaking Medicine News(10 mins):Health News:NIH to Launch human safety study of Ebola vaccine candidate 2Health News:NIH to Launch human safety study of Ebola vaccine candidate 3Health News:NIH to Launch human safety study of Ebola vaccine candidate 4Health News:NIH to Launch human safety study of Ebola vaccine candidate 5Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 2Health News:U.S. Vaccine Market: Opportunities and Threats by Transparency Market Research 3Health News:Mirror Mirror Beauty Boutique to Welcome Its First Patients 2Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 2Health News: Light Therapy a Good Option for Pre-Cancerous Skin Lesions, Study Says 3
... ... Hearing Institute (BHI) is urging families across America to make 2010 the year ... in response to new data that underscores the influence family members have in ... of nearly 47,000 households, more than half (51%) of new first-time owners of ...
... ... home top honors in American Spa Magazine,s 2009 Professional,s Choice Award in the Favorite ... ... 8, 2009 -- Oakworks® Inc., the premier U.S. manufacturer of wellness, spa, massage and ...
... , PHOENIX, Dec. 7 To standing cheers, ... (NNU) today unanimously endorsed the creation of the largest union ... and projected a major escalation in campaigns to expand union ... , "The promise of the future has arrived," said Karen ...
... Calif., Dec. 7 Patriot Scientific Corporation (OTC Bulletin ... its Board of Directors and will serve as chair ... 16 years of experience working in the software development ... and the delivery of consulting services for Cognizant Technology ...
... , LOS ANGELES, Dec. 7 Steeped in ... on Crystal Cruises, April 26 "Mind, Body and Spirit" ... the spiritual heritage of the region via personal meetings with ... meditation center, while guest health experts share insights on life ...
... , Department of Health Reminds At-Risk Pennsylvanians to ... federal Centers for Disease Control and Prevention, or CDC, ... flu vaccine to Pennsylvania to date, the state Department ... been distributed to 1,639 certified providers including pediatricians, family ...
Cached Medicine News:Health News:Study Finds Family Members Play Critical Role in Addressing Loved Ones' Hearing Loss 2Health News:Study Finds Family Members Play Critical Role in Addressing Loved Ones' Hearing Loss 3Health News:Study Finds Family Members Play Critical Role in Addressing Loved Ones' Hearing Loss 4Health News:Wellness Manufacturer Wins Two 2009 American Spa Awards 2Health News:Unanimous Vote Creates Largest RN Union in U.S. History 2Health News:Patriot Scientific Corporation Announces New Director 2Health News:Wellness Cruise Offers Crystal Guests 'Indian Ocean Insight' 2
(Date:8/28/2014)... PLYMOUTH MEETING, Pa. , Aug. 28, 2014 ... surgical community, patients, and media, both for the ... to patient safety. The quick deployment of surgical ... new technology are prompting facilities to evaluate their ... for the entire surgical team.    ...
(Date:8/28/2014)... 2014 Amgen (NASDAQ: AMGN ) ... (BLA) to the U.S. Food and Drug Administration (FDA) ... cholesterol. Evolocumab is an investigational fully human monoclonal antibody ... protein that reduces the liver,s ability to remove low-density ... 1 ­ The BLA ...
(Date:8/28/2014)... ALISO VIEJO , Kalifornien, 28. ... Inc., hat heute den Start der ... Investigational Device Exemption, Forschungsausnahmegenehmigung) zur Beurteilung ... Systems zur Embolisation von Aneurysmen („WEB") ... University of Tennessee, Department of Neurosurgery/Semmes-Murphey ...
Breaking Medicine Technology:Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 2Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 3Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 4Surgical Robot Risk and Safety: ECRI Institute and Hartford Hospital Launch New Education Series 5Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 2Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 3Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 4Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 5Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 6Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 7Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 8Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 9Sequent Medical kündigt Start einer IDE-Studie für das WEB System zur Embolisation von Aneurysmen bekannt 2Sequent Medical kündigt Start einer IDE-Studie für das WEB System zur Embolisation von Aneurysmen bekannt 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: