Navigation Links
FDA Investigating Weight-Loss Drug Over Reports of Liver Damage
Date:8/25/2009

ng it, U.S. Food and Drug Administration officials stressed Monday.

But the agency does recommend that patients tell their doctor if they are having symptoms such as weakness, fatigue, fever, jaundice or brown urine. Abdominal pain, nausea, vomiting, light-colored stools, itching and loss of appetite might also signal trouble.

Monday's move follows reports of 32 cases of serious liver injury, including six cases of liver failure, between 1999 and October of 2008.

More commonly, patients reported having jaundice, weakness and abdominal pain. For 27 patients, the symptoms were severe enough to require hospitalization.

Two of the cases occurred in the United States, the rest originated overseas.

In 10 years of being on the market, this isn't a great number, Pfanner noted.

The Drug Safety Oversight Board, part of FDA's Center for Drug Evaluation and Research, first looked into the issue in April. The agency stressed that there is no established association or evidence of a cause-and-effect relationship at this time.

The FDA first approved orlistat as a prescription medicine in 1999. In 2007, it became the first nonprescription drug approved to treat obesity in American adults.

The prescription version of the drug comes in 120-milligram capsules while the over-the-counter version is available in 60-milligram pills. Both versions are designed only to be used in conjunction with a reduced-calorie, low-fat diet by overweight adults aged 18 and older.

In 2006, the consumer advocacy group Public Citizen petitioned the FDA to remove Xenical from the U.S. market, not because of liver-related issues but because it might increase the risk of aberrant crypt foci, believed to be precursors to colon cancer.

The FDA's approval of the first over-the-counter drug for weight loss came as the United States and other western nations are struggling with an unprecedented obesity epidemic.
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations
2. FDA Investigating Safety of Asthma Drug Xolair
3. DEA Will Play Hardball in Investigating Michael Jacksons Doctors
4. Forensic Expert Investigating Chinese Drywall Issue
5. FDA Investigating Salmonella-Tainted Pistachios
6. Investigating a community where smoking rates are double the national average
7. Investigating causes of asthma attacks: New sensor system monitors environmental exposure
8. Micromet Receives Regulatory Approval to Conduct a Phase 2 Clinical Trial Investigating MT103 (MEDI-538) in Patients with Acute Lymphoblastic Leukemia
9. Consumer Specialty Products Association Responds to European Study Investigating Spray Products and Asthma
10. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
11. Study Finds Weight-Loss Surgery Safer Than Thought
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA Investigating Weight-Loss Drug Over Reports of Liver Damage
(Date:4/23/2014)... of endogenous neural precursor cells cannot alone compensate ... the perspective of neural plasticity, Dr. Yun Xiang ... observed the effects of functional electrical stimulation treatment ... of basic fibroblast growth factor and epidermal growth ... side. The researchers found that functional electrical stimulation ...
(Date:4/22/2014)... decades researchers have characterized a set of clock genes ... all types of species, from flies to humans. Over ... surmise there are more. A team from the Perelman ... if big-data approaches could find them. , To ... PhD, professor of Pharmacology and first author Ron Anafi, ...
(Date:4/22/2014)... Bethesda, MD, April 22, 2014: The Association for ... The Journal of Molecular Diagnostics on ... the baccalaureate and master,s levels of education. The ... (MLS) Curriculum Task Force of the AMP Training ... the critical need of educating future medical laboratory ...
(Date:4/22/2014)... April 2014. The latest scientific advances and emerging therapies ... 2014, the main annual meeting of the Heart Failure ... Journalists will also hear breaking news on acute heart ... Failure, which is part of the main congress. , ... Greece, at the Megaron Athens International Conference Centre (MAICC). ...
(Date:4/22/2014)... researchers have demonstrated the first size-based form of ... membranes of living cells. This unique physical approach ... critical to whether a cell lives or dies, ... obtained through conventional microscopy. , "We,ve developed membrane-embedded ... to both probe and manipulate membrane assemblies, including ...
Breaking Medicine News(10 mins):Health News:Bioinformatics profiling identifies a new mammalian clock gene 2Health News:AMP publishes curriculum recommendations for medical laboratory scientists 2Health News:The world's largest heart failure congress 2Health News:The world's largest heart failure congress 3Health News:First size-based chromatography technique for the study of livi 2Health News:First size-based chromatography technique for the study of livi 3
... 23 Nordic Omega-3 Fishies is Nordic Naturals newest product ... fun shape and great tasting natural tangerine flavor. Perfect for ... made with purified fish oil from anchovies and sardines, two ... gram Omega-3 Fish contains 455 mg of fish oil and ...
... 23 The European diabetes diagnostics market is poised ... (POC) tests offering tremendous growth potential. Heightened efforts to ... a key driver in market development. For instance, limited ... However, this challenge will be curtailed with more education ...
... ... , ... 23, 2009 -- Big Case Marketing, the global leader in marketing for dentists, dental marketing ... a Boston based coaching and consulting firm for dentists with advanced clinical training, has announced ...
... ... other FL health insurance options. , ... Miami, FL (PRWEB) June 20, 2009 -- Get Online Quotes, an ... Miami Dade Blue ( http://www.getonlinequotes.com/miami-dade-blue.html ) by Blue Cross Blue Shield of Florida. ...
... (ASX: CYT) announced today that it has filed an Investigational ... Administration (FDA) for its novel, potent orally active JAK2 inhibitor ... intends to commence a Phase I/II trial for CYT387 in ... scar tissue develops in the bone marrow. CYT387 is expected ...
... ANGELES, June 22 Mission Viejo general surgeon ... Chair of the Mutual Protection Trust (MPT) Board of Trustees. ... of American Physicians, Inc. (CAP). Dr. Cobo,s election occurred at ... Wormley, MD, a Glendora family practitioner who presided as chair ...
Cached Medicine News:Health News:Nordic Omega-3 Fishies from Nordic Naturals Offers Quality EPA and DHA for Children with 'Kid Pleasin' Taste 2Health News:Frost & Sullivan: Self-Monitoring and POC Diabetes Tests Reveal Potential for Significant Growth, Boosting the European Diabetes Diagnostics Market 2Health News:Frost & Sullivan: Self-Monitoring and POC Diabetes Tests Reveal Potential for Significant Growth, Boosting the European Diabetes Diagnostics Market 3Health News:One of a Kind Marketing and Sales Summit for Dentists Announced 2Health News:One of a Kind Marketing and Sales Summit for Dentists Announced 3Health News:Get Online Quotes Offers "Miami Dade Blue", A Blue Cross Blue Shield Plan As Part of Their Florida Health Insurance Offerings 2Health News:Get Online Quotes Offers "Miami Dade Blue", A Blue Cross Blue Shield Plan As Part of Their Florida Health Insurance Offerings 3Health News:Cytopia Lodges IND for JAK2 Inhibitor CYT387 2Health News:Dr. Juan Carlos Cobo Newly-Elected Chair of the Mutual Protection Trust Board of Trustees 2
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... & Forecast – Worldwide Analysis ... Pump Market Analysis ...
(Date:1/15/2014)... 2014  Zafgen, Inc., a leading biopharmaceutical company dedicated ... patients, today announced initial results from its Phase ... methionine aminopeptidase 2 (MetAP2), in patients with Prader-Willi ...  These results showed improvements in body weight, hunger-related ...
(Date:1/14/2014)... The Brandeis Medical Center, led by Dr. Emmanuel Brandeis ... affordable laser tattoo removal experience with the advanced Astanza Duality laser ... high quality cosmetic services with cutting edge medical technology and offering ... California has seen a dramatic increase in the presence ...
Breaking Medicine Technology:Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... has been designed specifically for the ... involved in ward rounds. It is ... dosages, and consultations that are requested ... Registrar during Ward round examinations and ...
... tracking and billing. This ... Handheld application, a complete ... CPT™ and ICD-9-CM codes ... Designed for any medical ...
In addition to the patient data OB-on-Call contains a comprehensive Medications list displaying related drugs by brand name, generic title, and usage description notes....
Archimedes is an innovative specialty calculator. Forget having to remember complicated formulas, just enter the values and out come the results....
Medicine Products: