Navigation Links
FDA Investigating Weight-Loss Drug Over Reports of Liver Damage
Date:8/25/2009

32 cases reported since orlistat came on market in 1999

TUESDAY, Aug. 25 (HealthDay News) -- As U.S. health officials announced Monday that they are investigating the weight-loss drug orlistat for possible incidents of liver damage, experts noted the drug might not even work well enough to warrant such potential risks.

Orlistat is available in the United States, both as a prescription product (Xenical) and as an over-the-counter medication (Alli).

Depending on the findings from the investigation, this could dramatically change the risk-benefit ratio of taking the drug, experts noted.

The weight loss gleaned from the drug is quite modest, about 5 kilograms, said Dr. Timothy Pfanner, an assistant professor of internal medicine at the Texas A&M Health Science Center College of Medicine and a gastroenterologist with Scott & White, in Temple, Texas.

"It's not a really effective drug. The benefit is not so great to begin with," he said, and additional risks might simply make the drug that much less attractive.

The other problem is that many obese people already have underlying liver problems, added Dr. Eugene Schiff, director of the Center for Liver Diseases at the University of Miami Miller School of Medicine.

"If they [the Food and Drug Administration] feel there is a subgroup, albeit a small one but a real one, that gets a serious liver injury, [that] often will be compounded by the fact they have underlying liver disease," he said. "It's very important that this be resolved quickly."

The issue is complicated by the fact that some patients are taking the drug in its over-the-counter form, meaning they are likely not being tracked and monitored by doctors for side effects.

At this point, there is no reason for consumers to stop taking the drug if they're already on it -- as long as they're using it as recommended -- and no reason for physicians to stop prescribi
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Boehringer Ingelheim to Commence Phase III Study Investigating the Role of BIBW 2992 as First-Line Treatment for Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR Mutations
2. FDA Investigating Safety of Asthma Drug Xolair
3. DEA Will Play Hardball in Investigating Michael Jacksons Doctors
4. Forensic Expert Investigating Chinese Drywall Issue
5. FDA Investigating Salmonella-Tainted Pistachios
6. Investigating a community where smoking rates are double the national average
7. Investigating causes of asthma attacks: New sensor system monitors environmental exposure
8. Micromet Receives Regulatory Approval to Conduct a Phase 2 Clinical Trial Investigating MT103 (MEDI-538) in Patients with Acute Lymphoblastic Leukemia
9. Consumer Specialty Products Association Responds to European Study Investigating Spray Products and Asthma
10. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
11. Study Finds Weight-Loss Surgery Safer Than Thought
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
FDA Investigating Weight-Loss Drug Over Reports of Liver Damage
(Date:11/26/2014)... 26, 2014 Dr. Rod J. ... Teaching Professor in the Department of Plastic Surgery ... fat compartments, fat grafting, and modern lift-and-fill facelifts ... annual conference held by the American Society of ... this underlying facial structure were explored in detail ...
(Date:11/26/2014)... Amy Norton HealthDay Reporter ... long believed their dogs understand what they,re saying, a new ... words in a human-like way. Past research has shown ... including the actual content and the emotional tone, said study ... deeper insight into the canine brain, according to Ratcliffe, a ...
(Date:11/26/2014)... Nov. 26, 2014 (HealthDay News) -- More than half ... their thinking and memory skills, a new study suggests. ... Neurology , "approximately 1.8 million Americans over the age ... of their cognitive [mental] abilities," study author Dr. Vikas ... Ann Arbor, said in a journal news release. ...
(Date:11/26/2014)... 26, 2014 The Deptford Center ... launched a partnership designed to improve the quality ... heart failure (CHF) patients in the South Jersey ... Lourdes Cardiology team will help CHF patients manage ... This partnership pairs the Cardiac Recovery program at ...
(Date:11/26/2014)... Raleigh, NC (PRWEB) November 26, 2014 ... types of materials science can cause mesothelioma that looks ... just posted a new article on the research. ... at the Fraunhofer Institute for Toxicology and Experimental Medicine ... nanotubes. While all of the rats eventually ...
Breaking Medicine News(10 mins):Health News:Dr. Rod J. Rohrich Discusses Facelifts at ASPS Annual Assembly 2Health News:Dr. Rod J. Rohrich Discusses Facelifts at ASPS Annual Assembly 3Health News:Your Dog Really Is Listening to You 2Health News:Your Dog Really Is Listening to You 3Health News:Too Few Americans Undergo Dementia Screening 2Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 2Health News:Advanced Heart Failure Recovery Program comes to Deptford Center for Rehabilitation and Healthcare 3Health News:Multi-walled Nanotubes Linked to Mesothelioma in New Study, According to Surviving Mesothelioma 2
... disease have same odds for condition, regardless of screening , , SUNDAY, ... run much less risk than previously believed of having silent myocardial ... a new study. , In fact, all adults aged ... of having a cardiac condition whether they are screened for the ...
... practices to have patients presenting with one checked ... The ties being found between type 2 diabetes and ... implications on public health, the International Diabetes Federation warns. ... a common breathing disorder, also have diabetes, recent studies ...
... First Echocardiography System to Acquire, Instantaneous, Non-Stitched Full-Volume Images of ... ... Heartbeat, TORONTO, June 7 Siemens Healthcare, (http://www.usa.siemens.com/healthcare ... in the world to acquire,non-stitched, real-time full-volume 3D images of the ...
... 2009 Event Becomes "Susan G. Komen GLOBAL Race ... The National Mall was,passionately pink this morning, as ... gathered for the 19th annual Susan,G. Komen National ... $4.9,million to fund breast cancer research and community ...
... China, June 6 /Xinhua-PRNewswire-FirstCall/ -- Renhuang,Pharmaceuticals, Inc. (Pink ... company in the People,s Republic of China ("PRC"),today ... trade show in,Harbin, China on May 29, 2008., ... medicines Renhaung,manufactories, are approved for the treatment of ...
... Carriage Services, Inc.,(NYSE: CSV ) today ... Investment,Profile", which can be found on Carriage,s website ... Investment Profile includes updated,discussions of Carriage,s business, operating ... more., The Company & Investment Profile is ...
Cached Medicine News:Health News:Older Diabetics' Risk of Cardiac Ischemia Lower Than Thought 2Health News:Doctors Urged to Look for Link Between Type 2 Diabetes, Sleep Apnea 2Health News:Siemens' New Ultrasound Platform Revolutionizes the Paradigm of Echocardiography 2Health News:Siemens' New Ultrasound Platform Revolutionizes the Paradigm of Echocardiography 3Health News:19th Annual Susan G. Komen National Race for the Cure(R) Draws Nearly 50,000 Participants, Celebrities; Brings Record Funds to National Capital Area 2Health News:19th Annual Susan G. Komen National Race for the Cure(R) Draws Nearly 50,000 Participants, Celebrities; Brings Record Funds to National Capital Area 3Health News:Renhuang Pharmaceuticals, Inc. Holds Trade Show for Tianma Pills; Signs Letters of Intent 2Health News:Renhuang Pharmaceuticals, Inc. Holds Trade Show for Tianma Pills; Signs Letters of Intent 3Health News:Carriage Services Updates Company & Investment Profile 2
(Date:11/26/2014)... , Nov. 26, 2014  CARsgen, a leader ... cell immunotherapy to treat a variety of cancers, today ... by BVCF, a China -based healthcare ... immunotherapy company focused on the development of new therapeutics ... with Shanghai Cancer Institute and Shanghai Renji Hospital, the ...
(Date:11/26/2014)... and NEW YORK ... As the leading distributor of market intelligence, ... new research report by IQ4I Research and Consultancy focusing ... To learn more about IQ4I Research visit: ... Active Pharmaceutical Ingredients Global Market – Forecast to ...
(Date:11/26/2014)... , Nov. 25, 2014  goBalto, Inc., the ... been recognized as a winner of Red Herring,s ... Global Top 100 North America award in 2013, marking ... technology landscape. Red Herring,s Top 100 Global ... promising new companies and entrepreneurs. Red Herring editors were ...
Breaking Medicine Technology:CARsgen Completes Series A Financing 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 3goBalto Selected as a 2014 Red Herring Top 100 Global Company 2goBalto Selected as a 2014 Red Herring Top 100 Global Company 3
... - - China , ... - welcomes world class biotechs and pharmas ... manufacturing technologies in China. The World Health Organization ... of China -- the State Food and Drug Administration (SFDA), along ...
... Sciences (NASDAQ: SRLS ), a global life ... the discovery, development and production of human diagnostics and ... new, differentiated panels to its product portfolio -- an ... Panel and an Anti-HIV-2 Performance Panel. ...
Cached Medicine Technology:VacChina 2011 - Bridging the China Vaccine Industry with the World Class Biotechnologies 2SeraCare Life Sciences Expands Product Portfolio 2SeraCare Life Sciences Expands Product Portfolio 3