Navigation Links
Compound Targets, Destroys Cancer Stem Cells in Mice
Date:8/13/2009

t a chemical called salinomycin destroyed both lab-generated cancer stem cells, as well as naturally occurring ones. When compared to paclitaxel, a common breast cancer chemotherapy drug, salinomycin reduced the number of cancer stem cells by more than 100-fold and inhibited breast tumor regrowth in mice.

Researchers also looked at the effect of salinomycin on genes that previous research has implicated in very aggressive tumors. The study showed salinomycin decreased the activity of these genes, while paclitaxel didn't.

Additional research is needed to determine exactly how salinomycin works to kill cancer stem cells and if it will be as effective in humans as it was in mice, researchers said.

More information

There's more on cancer stem cells at the U.S. National Cancer Institute.



-- Jennifer Thomas



Source: Aug. 13, 2009, news release, Whitehead Institute for Biomedical Research


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. First compound that specifically kills cancer stem cells found
2. New class of compounds discovered for potential Alzheimers disease drug
3. DSM Announces SafeBridge(R) Potent Compound Safety Certification
4. New Compounding Pharmacy Videos Provide Product Information, Teach Safety
5. Novel light-sensitive compounds show promise for cancer therapy
6. Neuromed Announces that Merck & Co., Inc. Terminates Research Collaboration and License Agreement for Compounds Targeting N-Type Calcium Channels
7. New antibiotics could come from a DNA binding compound that kills bacteria in 2 minutes
8. Natura Therapeutics and USF receive NIH grant to study green tea compound for Alzheimers
9. Bayer to Present Data on Development Compound BAY 73-4506 at 45th Annual Meeting of the American Society of Clinical Oncology
10. Research Findings on Nine GlaxoSmithKline Cancer Compounds to be Presented at ASCO 2009
11. GADA Points to Safety of FDA Approved Generics in Wake of Wellington Polo Horse Deaths from Compounded Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Compound Targets, Destroys Cancer Stem Cells in Mice
(Date:9/19/2014)... intact cells to treat and cure disease is ... is hindered by the inability of doctors and scientists ... these cells in patients without resorting to invasive procedures, ... 17 in the online journal Magnetic Resonance in ... Diego School of Medicine, University of Pittsburgh and elsewhere ...
(Date:9/19/2014)... Domestic violence occurs at least as frequently, and ... to opposite-sex couples, according to a review of ... Previous studies, when analyzed together, indicate that domestic ... lesbian, gay and bisexual individuals. However, a lack ... an incomplete picture of the true landscape, suggesting ...
(Date:9/19/2014)... 2014 As summer vacations end and everyone ... NY now reminds area patients about the reality and impact ... population affected by gum disease, there is simply not an ... 20 years Dr. Krishnan has treated patients with varying degrees ... patients that come in due to common symptoms such as ...
(Date:9/19/2014)... Shahram Majidi, M.D., a second-year resident in ... University School of Medicine and Health Sciences, received ... to study the presence of diffuse brain swelling ... , "According to epidemiological studies, intracerebral hemorrhage accounts ... but is the least treatable form of stroke, ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 BCC Research ... TECHNOLOGIES AND GLOBAL MARKETS , the global market for ... $13.9 billion by 2018, with a five-year compound annual ... segment is growing at a steady 3.8% CAGR. , ... presenting lower sales, coupled with the incidence of increasing ...
Breaking Medicine News(10 mins):Health News:A better way to track emerging cell therapies using MRIs 2Health News:Domestic violence likely more frequent for same-sex couples 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 2Health News:New York Periodontist Dr. Prabha Krishnan Now Raises Awareness about the Dangers of Untreated Decay, Gingivitis and Gum Disease During Self-Awareness Month 3Health News:GW researcher receives grant to study brain swelling following bleeding in the brain 2Health News:Global Market for Human Antifungal Therapeutics to Reach Nearly $13.9 Billion in 2018; Over-The-Counter (OTC) Segment Growing At 3.8% CAGR 2Health News:Global Market for Human Antifungal Therapeutics to Reach Nearly $13.9 Billion in 2018; Over-The-Counter (OTC) Segment Growing At 3.8% CAGR 3
... has apparently told his neighbours in the US, that charges ... due to negligence, have been dropped. Dr Patel, dubbed Dr. ... Hospital, Queensland. ,The government of Peter Beattie, Premier ... US. According to an AAP news report, Dr. Patel has ...
... said 22 cases of Chikungunya disease were confirmed in ... the 20 villages in Kolhapur district from where an ... found 22 cases from only 12 villages, which tested ... Pune's National Institute of Virology (NIV)," said Maharashtra health ...
... confessed to aborting over 250 female fetuses, adding he has lost ... his nursing home over the last decade. ,A.K. Singh ... in Pataudi town near here and discovered the dumped fetuses from ... has confessed that he has aborted more than 250 unborn female ...
... Moved by the plight of a one-year-old child whose ... , the Delhi High Court has asked the government ... not be paid to his parents for his upbringing. ... a division bench of Justices T.S. Thakur and S.N. ...
... describes how an impaired anti-inflammatory response plays a role ... ,Published in the Journal of Immunology, the study ... bind to specific receptors on cells and set off ... ,Interleukins, interferons, tumour necrosis factors, and some growth ...
... obesity, high blood pressure, high cholesterol, and inactivity are a ... 24. , The study was conducted by ... Reilly and Jesse Morrell, at the University of New Hampshire. ... from more than 800 undergraduates enrolled in a general-education nutrition ...
Cached Medicine News:Health News:Quack of Gurgaon Confesses of Aborting 250 Female Fetuses 2Health News:Child Seeks Compensation for Medical Negligence 2Health News:Cytokine Resistance Contributes to Pathology of Type 2 Diabetes 2
(Date:9/19/2014)... 19, 2014 Larry J. Merlo , President ... will speak before the National Press Club in ... recent move to stop selling tobacco products and its leadership ... health. "Dramatic changes in our health care system ... government," Merlo has said. "CVS Health has a truly unique ...
(Date:9/19/2014)... , Sept. 19, 2014  Pressure BioSciences, ... announced it has received and approved all parts ... instruments and has begun to manufacture the new ... instrument will be ready for shipment by mid-October ... and released at a rate of about one ...
(Date:9/19/2014)... ORLANDO, Fla. , Sept. 19, 2014 ... continues to grow, with the publication of two papers ... Otolaryngology – Head and Neck Surgery ... of both objective and subjective measures of sleep disordered ... therapy for the reduction in obstructive sleep apnea severity ...
Breaking Medicine Technology:CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 3Pressure BioSciences Announces Completion of the First Phase of Its Commercialization Plan for the Barozyme HT48, the Company's Recently Released High Throughput PCT-based Instrument System 2Pressure BioSciences Announces Completion of the First Phase of Its Commercialization Plan for the Barozyme HT48, the Company's Recently Released High Throughput PCT-based Instrument System 3New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 2New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 3New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 4
... Choices for This Common and Successful Surgery, ... the September issue of Mayo Clinic Health Letter. ... wish. Reprinting is allowed for a,fee. Mayo Clinic ... information as your editorial policies permit: Visit, http://www.HealthLetter.MayoClinic.com ...
... Clinical Lab,Products magazine features Biomoda, Inc. ... its proprietary early lung cancer screening,assay as ... the cancer diagnostic,technology. The August national magazine ... assay,s simplicity that leads to large scale ...
Cached Medicine Technology:September 2008 Mayo Clinic Health Letter Highlights Cataract Removal, Severe Headache and Dual Energy X-Ray Imaging 2September 2008 Mayo Clinic Health Letter Highlights Cataract Removal, Severe Headache and Dual Energy X-Ray Imaging 3September 2008 Mayo Clinic Health Letter Highlights Cataract Removal, Severe Headache and Dual Energy X-Ray Imaging 4Clinical Lab Products Magazine Features Biomoda 2
23 gauge thin wall irrigation. 25 gauge thin wall aspiration. Angled 30 degree shaft 8 mm from tip to bend. Irrigation tip set 0.5 mm behind aspiration tip. Dual hub construction. Polished finish. Ov...
This specially designed 23 gauge spoon-shaped cannula is connected to a balanced salt solution bottle and with a low-flow of fluid, is designed to allow a controlled cleaning of the stromal interface...
... with five legs for extra stability. Adjustable ... vertical travel 6"). 2" ball bearing swivel ... retardant upholstery, available in black vinyl as ... Features a contoured, padded, upholstered backrest, with ...
Anterior Stromal Puncture Cannula, 25 g. For treatment of recurrent corneal erosion. Overall length 24 mm. 5/box....
Medicine Products: