Navigation Links
Commonly used drug can limit radiation damage to lungs and heart for cancer patients
Date:4/21/2013

Geneva, Switzerland: Unavoidable damage caused to the heart and lungs by radiotherapy treatment of tumours in the chest region can be limited by the administration of an ACE inhibitor, a drug commonly used in the treatment of cardiovascular disease, a group of Dutch researchers have found. [1]

Common cancers such as breast, oesophagus, lung, and Hodgkin's lymphoma are frequently treated with radiotherapy, but the radiation dose that can be given safely is limited by the sensitivity of the health lung tissue which is also irradiated.

The lung is a particularly complex and sensitive organ and strategies for protecting it from radiotherapy damage, apart from limiting the dose given and, therefore, the efficacy of the treatment, are few. Presenting the research to the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO) today (Sunday), Dr Sonja Van der Veen, MSc, from the University Medical Centre, Groningen, The Netherlands, said that she had set out with colleagues to see whether the use of an ACE inhibitor could protect against early radiation-induced lung toxicity (RILT). Previous studies had shown that damage to blood vessels can play an important role in the development of RILT [2], so the researchers irradiated the lungs, heart, or heart and lungs of rats and administered the ACE inhibiter captopril immediately after treatment. The rats' lung functions were then measured at two-weekly intervals.

"After eight weeks, when early lung toxicity is usually at its height, we found that captopril improved the rats' heart and lung functions, but we were surprised to find that this only occurred when the heart was included in the irradiation field," said Dr Van der Veen. "This was not due to protection of the lung blood vessels, which were equally damaged with or without captopril. So we investigated further and found that the captopril treatment improved the heart's function and decreased the level of fibrosis in the he
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society for Radiotherapy and Oncology (ESTRO)
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Commonly used cholesterol calculation underestimates heart disease danger for many
2. UV Flash Infection Control Unit Steps onto the Healthcare Market, with a Quick and Effective Way to Disinfect Virtually any Item Commonly Found in Medical Facilities
3. New UAlberta research shows commonly prescribed medications could have adverse effects
4. Condition Commonly Seen in Aging May Alter Brain Function
5. Commonly used painkillers may protect against skin cancer
6. Memory, the adolescent brain and lying: The limits of neuroscientific evidence in the law
7. Career Confidential Announces Their Cover Letter Podcast Viewing Complimentary for a Limited Time
8. Asia-Pacific Seasonal Influenza Vaccine Market to 2018 - Positive Impact of Government Support Offset by Limited Production Capacity : MarketResearchReports.biz
9. Ability to think about thinking not limited to humans
10. iPad Ultra Thin Aluminum Bluetooth Keyboard Case Released by iGearUnlimited
11. Kwiksure Discovers Uses and Limitations of Vehicle GPS in Hong Kong
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... WA (PRWEB) July 31, 2014 ... family practice provider? Community Health Center of Snohomish ... “ Pediatricians vs. Family Doctors ”. Many adults ... are available to them. Community Health Center hopes ... similarities and differences between the two. , ...
(Date:7/31/2014)... The shale gas development that has vaulted ... U.S. natural gas production has raised concerns that local ... similar to previous resource extraction experiences in Pennsylvania’s history. ... & Jefferson College’s (W&J) Center for Energy Policy & ... that the gas boom in Pennsylvania is still underway, ...
(Date:7/31/2014)... OR (PRWEB) July 31, 2014 Sales in ... from 2013 to 2014, according to radio talk show host ... been experiencing rapid growth since 1990. The US economy in ... Kleyne Hour Power of Water radio show, reported this information ... Live Foods, a worldwide manufacturer of organic and natural food ...
(Date:7/31/2014)... 2014 According to new research ... Mycoprotein), by Type (Tofu, Tofu-Based Product, Tempeh, TVP, ... Global Trends & Forecasts to 2019", defines and ... analysis and forecasting of the market value of ... report also identifies the driving and restraining factors ...
(Date:7/31/2014)... 31, 2014 Care Communications, Inc., (CARE) ... firm, has received the Elite Award for “Recruitment, Selection ... one of twelve elite awards presented as part of ... Work For” 2014 awards competition. This marks the ... Award in the competition. CARE has also been chosen ...
Breaking Medicine News(10 mins):Health News:Community Health Center of Snohomish County Reveals the Differences Between Pediatricians and Family Practice Providers 2Health News:Pennsylvania’s Shale Gas: Examining the Boom and Bust Cycle 2Health News:Pennsylvania’s Shale Gas: Examining the Boom and Bust Cycle 3Health News:Organic Food Industry Grew 12% in 2013-2014 Reports Sharon Kleyne Hour Power of Water Host 2Health News:Organic Food Industry Grew 12% in 2013-2014 Reports Sharon Kleyne Hour Power of Water Host 3Health News:Meat Substitutes Market Worth $4,622.4 Million by 2019 - New Report by MarketsandMarkets 2Health News:Meat Substitutes Market Worth $4,622.4 Million by 2019 - New Report by MarketsandMarkets 3Health News:Care Communications, Inc. Named an Elite Award Winner Among Top Chicago Employers 2
... , , HOFFMAN ESTATES, Ill., July 16 ... of America,s top medical institutions in the annual America,s Best Hospitals list ... magazine. St. Alexius Medical Center was ranked among the top 50 ... , , (Photo: http://www.newscom.com/cgi-bin/prnh/20090716/CG47487 ...
... , , CARLSBAD, Calif., July 16 ... and microbial nucleic acid purification, announces the launch of an innovative ... genomic DNA from food cultured microorganisms. , , ... other commercial food kits with its easy-to-use protocol that allows for ...
... , , PALO ALTO, Calif., ... has been elected chairman of the company,s Board of Directors. , ... the biotechnology industry, and as the former chairman of Connetics Corporation ... leadership and success to TOPICA, as well as an exceptional knowledge ...
... , CHICAGO, July 16 Lexington Health ... services for those needing sub-acute medical and rehabilitative services as ... directors has named Dale Zaletel as the company,s new chief ... held the position of Chief Operating Officer since joining Lexington ...
... , Gamers Engage Memory, Attention, Processing Skills ... /PRNewswire-USNewswire/ -- The MS Technology Collaborative has created a ... brain power. The Collaborative, an alliance of Bayer HealthCare Pharmaceuticals, Microsoft, ... a free suite of online cognitive games for the MS community. ...
... , , , ... one of the nation,s leading domestic manufacturers of prescription foot ... awarded the prestigious Employer of the Year award, which is ... recognizes private sector employers that provide outstanding employment opportunities and ...
Cached Medicine News:Health News:St. Alexius Medical Center Named to America's Best Hospitals Rankings 2Health News:MO BIO Laboratories, Inc. Launches PowerFood(TM) Microbial DNA Isolation Kit 2Health News:TOPICA Elects G. Kirk Raab as Chairman of the Board 2Health News:Lexington Health Care Names New Chief Executive Officer 2Health News:Technology Collaborative Launches Online Game to Exercise Brain Power of People with Multiple Sclerosis 2Health News:Technology Collaborative Launches Online Game to Exercise Brain Power of People with Multiple Sclerosis 3Health News:Technology Collaborative Launches Online Game to Exercise Brain Power of People with Multiple Sclerosis 4Health News:PAL Health Technologies Wins State-Level Prestigious 'Employer of the Year' Award 2
(Date:7/30/2014)... , July 30, 2014 /PRNewswire-iReach/ -- Transluminal Technologies ... medical device company, has announced today that they ... CD™ Vascular Closure Device. Velox CD™ provides a ... following percutaneous femoral procedures. The single size velox ... in size from 5F to 8F.  ...
(Date:7/30/2014)... 2014  InnoPharma, Inc. today announced the first generic ... of Zyprexa® injection), in Canada.  Olanzapine is indicated for ... patients with schizophrenia or bipolar I mania. ... has entered into an agreement with Sandoz Canada Inc., ... use, sell, market and distribute Olanzapine Injection in ...
(Date:7/30/2014)... , July 30, 2014  Regeneron Pharmaceuticals, Inc. ... and NYSE: SNY ) today announced that ... people with hypercholesterolemia met their primary efficacy endpoint of ... cholesterol (LDL-C) at 24 weeks compared to placebo or ... PCSK9 (proprotein convertase subtilisin/kexin type 9). In ...
Breaking Medicine Technology:Transluminal Technologies receives CE Mark approval for velox CD(TM) vascular closure device 2InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 2Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 3Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 4Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 5Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 6Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 7Regeneron and Sanofi Report Positive Top-Line Results from Nine Phase 3 Trials of Alirocumab in People with Hypercholesterolemia 8
... Masimo (Nasdaq: MASI ), ... Masimo rainbow Acoustic Monitoring™ , and Masimo ... announces an expanded supplier agreement that adds Masimo rainbow ... contract with Premier Purchasing Partners, LP, the group purchasing ...
... Ala., Aug. 19 The Specialty Pharma Association announces its Fall ... be held September 15-17, 2010 at the San Diego Marriott Hotel ... Conference will include the following: Carole DeRoche, President ... Vice President Kantar Health Kurt ...
Cached Medicine Technology:Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 2Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 3Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 4Premier Members to Benefit from Full Line of Market-Leading Masimo rainbow Pulse CO-Oximetry Solutions with New Agreement 5
... TruFit® CB Plugs use OBIs ... a scaffold for tissue repair that ... stable. A patented composite of ... the PolyGraft® material can be fabricated ...
The TruGraft BGS Granules are to be used in bone void filling of surgically or traumatically created osseous defects....
... the first to manufacture a diode pumped ... to announce their newest addition, the VITRA. ... the problem that many doctors face when ... No larger than a shoe box, this ...
... Resistant Tips offer a safe alternative to ... designed for applications such as PCR(a), pipetting ... ART Tips are excellent for tissue culture, ... ART Tips prevent aerosol contaminants and liquids ...
Medicine Products: