Navigation Links
Cold sore linked to mutation in gene, study suggests
Date:9/16/2013

Why some people are troubled by cold sores while others are not has finally been explained by scientists.

Cold sores affect around one in five people but, until now, no one has been sure why some are more prone to the virus that causes them.

Researchers at the University of Edinburgh have found that people affected by cold sores have a mutation in a gene, which means their immune system is not able to prevent them from developing.

Cold sores are caused by a strain of the herpes simplex virus herpes simplex virus type 1 (HSV-1). Between 80 and 90 per cent of people are infected with the virus, but only about a quarter of them get frequent cold sores.

Scientists analysed thousands of genes to identify which ones expressed the proteins needed by the body's immune system to prevent the virus from becoming active and as a result cold sores from developing.

They then looked at blood samples from people with cold sores and found that one of the genes previously identified IL28b was mutated.

This genetic mutation means that the body is not able to mount an adequate immune response to the virus, which results in cold sores.

The gene identified is also linked to treatment responses for hepatitis C patients. If this gene is mutated, patients are less likely to respond as well to treatment. The link is further evidence that a single genetic mutation can be linked to different viruses.

The study, published in the journal Plos Pathogens, was funded by the Medical Research Council, the Biotechnology and Biological Sciences Research Council, the Wellcome Trust and the European Union.

Professor Juergen Haas, of the University of Edinburgh's Division of Pathway Medicine, said: "Most people carry the cold sore strain of the herpes simplex virus, but until now we never knew why only some of them develop cold sores.

"Knowing that susceptibility to the virus involved relates
'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Antibiotics Linked to Retinal Detachment Risk
2. Pesticides May Be Linked to Slightly Smaller Babies, Shorter Pregnancies
3. Pharmacy Robots Linked to Bacterial Contamination of Drugs
4. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
5. Dental X-Rays May Be Linked to Benign Brain Tumors
6. In Mice, Drug Reverses Symptoms of Condition Linked to Autism
7. Huntingtons Disease Linked to Reduced Cancer Risk in Study
8. Study finds significant skull differences between closely linked groups
9. Researchers Map Brain Regions Linked to Intelligence
10. Swallowing exercises linked with short-term improvement among patients with head and neck cancer
11. Anxiety Linked to Smarts in Brain Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... For Dr. Iris Hunter, a job is more ... of her life’s mission. Her extensive experience in the nonprofit ... FirstLight HomeCare, make it clear that Hunter’s mission is to ... work makes a difference in the lives of others,” Hunter ... much research, I felt ready to start on this journey ...
(Date:10/22/2014)... Lexington, Kentucky (PRWEB) October 22, 2014 ... an agreement that will change the current location of ... Road to South Limestone across from the University of ... be a state-of-the-art ambulatory care center, owned and operated ... meet the orthopaedic needs of children and their families ...
(Date:10/22/2014)... With the Affordable Care Act (ACA) open ... American Institutes for Research (AIR) finds that three out of ... insurance, but 42 percent say they are not likely or ... up for coverage. , The AIR survey found wide gaps ... to calculate correctly how much they owe for a routine ...
(Date:10/22/2014)... Healthcare professionals who are looking for ... home or on-the-go via laptops, tablets or mobile ... premium Seminar-on-Demand CE courses. The new courses add ... hours of CE course offerings, allowing therapy ... such a diverse library, there’s something for everyone. ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Lintelus, Inc., ... Sr. Vice President of Sales, will be speaking on ... Meetings Technology Expo on October 28, at the Holiday ... hosting a booth as well as a Tech Demo ... Meeting can create a more engaging event experience. , ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2
... the drugs in primary care , TUESDAY, May 18 (HealthDay ... to them and stay that way for as long as ... 24 studies of antibiotic resistance, in which people develop a ... The studies looked at use of the drugs in primary ...
... Bobbie ... They had to sell their current home, but the new residence wasn,t ready for them to ... with a private, dignified, and stress-free home sale. , ... (PRWEB) May 19, 2010 -- Bobbie Benjamin and her husband Del had lived in ...
... ... Driving. , ... 2010 -- On May 13, 2010, Georgia Governor Sonny Perdue signed into law House Bill ... an effort to offset some of the State’s growing deficit. This new law dramatically affects ...
... Web ... , ... May 19, 2010 -- ORCS Web Inc., a specialist in Microsoft Windows-based internet hosting ... Microsoft’s newly released WCF RIA Services for Silverlight 4 has been made available on ...
... ... will appear in the May issue of San Diego Magazine, as well as be included in the ... (PRWEB) May ... the May issue of San Diego Magazine and will also be included in the 2010 database of ...
... 19, 2010 Heavy alcohol use and binge drinking could ... UT Southwestern Medical Center suggests. In a study ... the more alcohol a man consumed, the higher his risk ... no alcohol. "If this relationship continues to be confirmed, ...
Cached Medicine News:Health News:Senior Home Sale Client Calls SASH's Service 'A Godsend' 2Health News:Senior Home Sale Client Calls SASH's Service 'A Godsend' 3Health News:Senior Home Sale Client Calls SASH's Service 'A Godsend' 4Health News:Georgia DUI Lawyers Scramble to Publicize Existence of New Appeal Fee of $150 for All DUI-Related Administrative License Suspension Cases 2Health News:Georgia DUI Lawyers Scramble to Publicize Existence of New Appeal Fee of $150 for All DUI-Related Administrative License Suspension Cases 3Health News:ORCS Web, Inc Makes Available WCF RIA Services 2Health News:San Diego Dentist Dr. Ernest C. Wong Voted a “Top Dentist” 2Health News:Heavy alcohol use, binge drinking, might increase risk of pancreatic cancer, researcher reports 2Health News:Heavy alcohol use, binge drinking, might increase risk of pancreatic cancer, researcher reports 3
(Date:10/22/2014)... , Oct. 21, 2014  Early symptoms of ... or unnoticed, but new technology, coupled with yearly, ... leading to earlier detection of eye diseases, including ... million Americans. If left untreated, these diseases can ... Recently, optometric researchers have deployed ...
(Date:10/22/2014)... -- Sanomedics International Holdings, Inc. (OTCQB: SIMH) – According ... Data Services, demand for thermometers is expected to grow ... demand for more accurate digital thermometers continues.  ... market for thermometers, and one of the companies serving ... Inc. Sanomedics International Holdings designs, develops, markets, ...
(Date:10/22/2014)... NORWALK, Conn. , Oct. 22, 2014  Recently ... (GERD) have bolstered the already substantial database of evidence. ... and adoption of Stretta therapy for sufferers ... of clinical evidence supporting Stretta therapy as ... coverage policies that make Stretta therapy available to nearly ...
Breaking Medicine Technology:Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2Recent Clinical Study Data Confirms Efficacy of Stretta Therapy - Spurs Additional Insurance Coverage and Financing Round 2
... The Medtronic InSync II Marquis incorporates ... ICD therapy. Cardiac resynchronization benefits include ... pacing outputs to unique patient needs. ... functions that help physicians manage heart ...
... Contak Renewal 3 cardiac resynchronization ... therapy and cardiac resynchronization therapy. ... (RV) and left ventricular (LV) ... reduce irregular ventricular intervals during ...
... (MST) is a surgical technique designed to ... in a cortical area that cannot be ... deficit. In this technique, fine parallel cuts ... disrupt the initial spread of the seizure ...
A complete system of cannulas, needles and rasps specifically designed for inside-out meniscal repair procedures....
Medicine Products: